Protein Alignment Kif19A and kif19

DIOPT Version :10

• Sequence 1: NP_996208.1
• Gene: Kif19A / 41717
• FlyBaseID: FBgn0038205
• Length: 750
• Species: Drosophila melanogaster
• Sequence 2: XP_031750317.1
• Gene: kif19 / 100145702
• XenbaseID: XB-GENE-5954822
• Length: 1001
• Species: Xenopus tropicalis
• Alignment Length: 772
• Identity: 277/772 - (35%)
• Similarity: 429/772 - (55%)
• Gaps: 110/772 - (14%)

  Fly    31 AQEERLVVAVRVRPSMEATERCIEVISGGSLLY-----------------DD---GGKSRPRQYS 75
            ::|::|.||:|:||..||     |:..|.:::.                 ||   ..:||.:.|.
 Frog     7 SKEQQLTVALRIRPINEA-----ELGEGATIIAHKVDEQMVVLMDPMEDPDDVLRANRSREKSYM 66

  Fly    76 YDHVFRENDSQEQVYKTTTAPLVRDVLNGLNAAVFAYGATGSGKTHTMLGPVPRKKPQTSDRAPP 140
            :|..|....:|:.||:.||..|:..|::|.||.|||||.||.|||:||||         :|..|
 Frog    67 FDVAFDYTATQDTVYRLTTKGLIEGVISGYNATVFAYGPTGCGKTYTMLG---------TDWEP- 121

  Fly   141 TASCDSTDVSSQDIGLMVRAIEDIFSHI-ESAEAYSCRVSISYLEIYNELIRDLLNPG-GPLELR 203
                          |:.:|.:.|:|..| |:::.....|.:||:|||||:|||||||. |.|:||
 Frog   122 --------------GIYIRTLNDLFKAIEETSDDMEYEVLMSYMEIYNEMIRDLLNPSLGYLDLR 172

  Fly   204 EDHRGQRITVAGLSEITTSSRKEVVSLLLKGNKARTMEPTAANQTSSRSHALLSIMVQARTPL-- 266
            ||.:|. |.|||::|::|.:.||::.||:||||.||.||||||:|||||||:|.:.|:.::.:
 Frog   173 EDSKGV-IQVAGITEVSTINAKEIMQLLMKGNKQRTQEPTAANKTSSRSHAILQVTVRQKSRVKN 236

  Fly   267 ---GTKQGRLFLTDLAGSERAKKTKNRGKRLQEGAHINRSLLALGNVINGLS--GGARYVNYRDS 326
               ..:.||||:.||||||||.:|:|||:|::||||||||||||||.||.||  ||.:|||||||
 Frog   237 ITQEVRVGRLFMIDLAGSERASQTQNRGQRMKEGAHINRSLLALGNCINALSERGGNKYVNYRDS 301

  Fly   327 KLTRLLKEALSGRCKTVMIAHVAPESKHRDETKNTLVYADRANSITTKLQNSVYIDEFKDFPTKH 391
            |||||||::|.|..:||||||::|.|...:|::|||.|||||.:|.|:::.::.   ...:....
 Frog   302 KLTRLLKDSLGGNSRTVMIAHISPASTSFEESRNTLTYADRAKNIKTRVKRNLL---NVSYHIAQ 363

  Fly   392 YQSLVSELRDEVSRLRTKMLTERPRSGAAAAAAAAAASGSAGTAGSGAGSEAVQEQDEQRKTELR 456
            |.|::|:||.|:.||:.|:..:..:...:..:.............|..|           :.|:.
 Frog   364 YTSIISDLRKEIQRLKEKIDEQGLKQLRSEKSDIRNIQAEVQLHSSPYG-----------RHEME 417

  Fly   457 YLREQIVLTFKQQMKLRRKLLEAESHLLGLELDAERQHMIISHWQ----GRIGKLYDAM-----G 512
            .|:||::..|::||.:||:|:|.|:..:.::::..|..:||:.|:    .|..|..|.:     |
 Frog   418 QLKEQLIRAFREQMDIRRQLMEIENSSMEMQMETSRHFLIIADWEQEKARRARKWKDELRKETYG 482

  Fly   513 DDDIESEGSVA-----------LKNAWGELAAIEKETRRYKEIRERTEHELEQCRQKGVKLEDEL 566
            .||.|.:....           :..|...:..:|.:..:.:..:...|......||:..:||:.|
 Frog   483 KDDSEKDSDTGDEQSDIIEPPEVTTARETIQILEGDQSKLRRQKLELEKRFRDIRQRARRLEEAL 547

  Fly   567 PERISSDEERELLALLCRVHELEADKVSLQAERLARQAELRRRDLQLLRAERQRRLCEDIISSQR 631
            |:||||:::||:|:|||:|||||.:...:|:..|.:...:|:::..:.|.|:.|.||::||..||
 Frog   548 PKRISSEDQREILSLLCKVHELEIENTEMQSHALLKDNMIRQKNHMVQRFEQHRSLCDEIIKQQR 612

  Fly   632 RLIEEGNVDLPDELRELYGLYQQEIHAGVVTP----STSNYERKLP--PIYTAGSD--SPGSSSS 688
            |:|.:.|:.:|.:|.:||.||.:|:..||:..    :..:.:..||  |..||..:  .|.|...
 Frog   613 RIIYDHNLTVPHQLEDLYELYFRELEEGVLDKVAVLALKDSQSSLPKIPYLTAEENLQEPDSDQE 677

  Fly   689 SEWSPASPLPQIDNQMDPVDRVMGPPVNPRLPRLSAATSANVPAGGSRRPSLRVARN 745
            |..:..|     ||: :|:.|   ......|||:.:.|..:........|..|..:|
 Frog   678 SVRTFGS-----DNR-NPIHR---DSYKNLLPRILSETDGDTNKVFKTSPRARHLKN 725

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kif19A	NP_996208.1	Motor_domain	35..371	CDD:473979	172/364 (47%)
		SMC_prok_B	<393..672	CDD:274008	81/302 (27%)
kif19	XP_031750317.1	KISc_KIP3_like	11..346	CDD:276821	172/364 (47%)
		SMC_N	<361..>615	CDD:481474	71/264 (27%)