DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12402 and AT1G80570

DIOPT Version :9

Sequence 1:	NP_001303481.1	Gene:	CG12402 / 41714	FlyBaseID:	FBgn0038202	Length:	671	Species:	Drosophila melanogaster
Sequence 2:	NP_974191.1	Gene:	AT1G80570 / 844396	AraportID:	AT1G80570	Length:	480	Species:	Arabidopsis thaliana

Alignment Length:	498	Identity:	109/498 - (21%)
Similarity:	196/498 - (39%)	Gaps:	131/498 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   180 RNLDGKLPNLKVLTIATTM-SMDDQHLAAMD-----DLDMKQ-FSHLVGFECDGV-SLDAVLKMR 236
            |.:| :||:..|..|.:.: :.||::..::.     .||.:| :|..:|  |..| :.||:|.:
plant    12 RQMD-ELPDHLVWDILSKLHTTDDRNSLSLSCKRFFSLDNEQRYSLRIG--CGLVPASDALLSL- 72

  Fly   237 MLLQLRRTEN--KVQLRH---LQFEFRRNNENALLDVLQDHAETLVCVNLFF------------- 283
                .||..|  ||::.:   :....::.::..|| ||..:..:|..:.|.|
plant    73 ----CRRFPNLSKVEIIYSGWMSKLGKQVDDQGLL-VLTTNCHSLTDLTLSFCTFITDVGIGHLS 132

  Fly   284 SC----------SPGI------DTREWCRAFENMHNLRTLKLSGNCHLVLLEAVLRAVPESAPIR 332
            ||          :|.|      .....|:....:|.:|.|.:                   |.:.
plant   133 SCPELSSLKLNFAPRITGCGVLSLAVGCKKLRRLHLIRCLNV-------------------ASVE 178

  Fly   333 QLDLTGMLSLTNEL------------LLYVAGKWQSTLKVLDLMFCVQLNANCIDALRQLS---- 381
            .|:..|.|....||            |:.:...|:   |:..|.|.|..|...:....||.
plant   179 WLEYFGKLETLEELCIKNCRAIGEGDLIKLRNSWR---KLTSLQFEVDANYRYMKVYDQLDVERW 240

  Fly   382 -------GRLEALTMAYCRELTGTGLLQGLAGDINYSLQELHLEETIFLDESSMCQLLERLPNLR 439
                   ..|..|::..|....|.||...|....|  |::|||:....:.:|.:..|:::..:||
plant   241 PKQLVPCDSLVELSLGNCIIAPGRGLACVLRNCKN--LEKLHLDMCTGVSDSDIIALVQKASHLR 303

  Fly   440 RLS-----------LDNCRQAVTDRTMATICQYQTRLRNLNIEYCMKITDQGLMGYGDTPYPIS- 492
            .:|           |:|....:||.:::.|.|:.::|.:..|.:    :|      |:.|...|
plant   304 SISLRVPSDFTLPLLNNITLRLTDESLSAIAQHCSKLESFKISF----SD------GEFPSLFSF 358

  Fly   493 RLRGL---------KELNLRGCRNVTDSSLMVGLKLPELRALSLGYCNRLTSEGFEALTQNCPSL 548
            .|:|:         :||:|.......|..:.......:|..|.|.:|..::.||. .|....|||
plant   359 TLQGIITLIQKCPVRELSLDHVCVFNDMGMEALCSAQKLEILELVHCQEVSDEGL-ILVSQFPSL 422

  Fly   549 EALCVSSCMAVDDETVLNIVSNLKRLRVLNLSNCTKLTLQSIH 591
            ..|.:|.|:.|.|:.:..:|.:.| |.:|.:.:|.:::.:.:|
plant   423 NVLKLSKCLGVTDDGMRPLVGSHK-LELLVVEDCPQVSRRGVH 464

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12402	NP_001303481.1	F-box	75..117	CDD:279040
		leucine-rich repeat	281..303	CDD:275381	7/50 (14%)
		LRR_RI	<297..482	CDD:238064	44/218 (20%)
		leucine-rich repeat	304..330	CDD:275381	2/25 (8%)
		leucine-rich repeat	331..357	CDD:275381	7/37 (19%)
		leucine-rich repeat	358..379	CDD:275381	5/20 (25%)
		leucine-rich repeat	384..409	CDD:275381	7/24 (29%)
		leucine-rich repeat	412..437	CDD:275381	6/24 (25%)
		AMN1	430..595	CDD:187754	43/183 (23%)
		leucine-rich repeat	438..464	CDD:275381	9/36 (25%)
		leucine-rich repeat	465..496	CDD:275381	7/31 (23%)
		leucine-rich repeat	497..521	CDD:275381	4/32 (13%)
		leucine-rich repeat	522..547	CDD:275381	7/24 (29%)
		leucine-rich repeat	548..573	CDD:275381	7/24 (29%)
		leucine-rich repeat	574..599	CDD:275381	4/18 (22%)
AT1G80570	NP_974191.1	AMN1	77..309	CDD:187754	50/256 (20%)
		leucine-rich repeat	79..111	CDD:275381	6/32 (19%)
		leucine-rich repeat	112..136	CDD:275381	5/23 (22%)
		leucine-rich repeat	137..162	CDD:275381	3/24 (13%)
		leucine-rich repeat	163..188	CDD:275381	7/43 (16%)
		leucine-rich repeat	189..226	CDD:275381	8/39 (21%)
		AMN1	241..435	CDD:187754	49/206 (24%)
		leucine-rich repeat	250..275	CDD:275381	7/24 (29%)
		leucine-rich repeat	276..301	CDD:275381	6/24 (25%)
		leucine-rich repeat	302..339	CDD:275381	9/36 (25%)
		leucine-rich repeat	340..368	CDD:275381	8/37 (22%)
		leucine-rich repeat	372..396	CDD:275381	4/23 (17%)
		leucine-rich repeat	397..421	CDD:275381	7/24 (29%)
		leucine-rich repeat	422..446	CDD:275381	7/23 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1947
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR13318
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910