DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12402 and AT5G27920

DIOPT Version :9

Sequence 1:	NP_001303481.1	Gene:	CG12402 / 41714	FlyBaseID:	FBgn0038202	Length:	671	Species:	Drosophila melanogaster
Sequence 2:	NP_568502.1	Gene:	AT5G27920 / 832858	AraportID:	AT5G27920	Length:	642	Species:	Arabidopsis thaliana

Alignment Length:	505	Identity:	119/505 - (23%)
Similarity:	206/505 - (40%)	Gaps:	98/505 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   154 CRQLENFLRLVGHEVKHLQVRHAPVFRNLDGKLPNLKVLTIATTMSMDDQHL-------AAMDDL 211
            |:.|::.      :|.:|::.:..: |:: ..|..|:||.:.:...:||..|       .::.::
plant   197 CKGLKSL------DVSYLKITNDSI-RSI-ALLVKLEVLDMVSCPLIDDGGLQFLENGSPSLQEV 253

  Fly   212 DMKQFSHLVGFECDGVSLDAVLKMRMLLQLRRTENKVQLRHLQFEFRRNNENALLDVLQDHAETL 276
            |:.:        ||.|||..      |:.:.|....:||                 :...|
plant   254 DVTR--------CDRVSLSG------LISIVRGHPDIQL-----------------LKASH---- 283

  Fly   277 VCVNLFFSCSPGIDTREWCRAFENMHNLRTLKLSG----NCHLVLLEAVLRAVPESAPIRQLDLT 337
             ||:..        :..:.:..:.:.:|:|:.:.|    :..||.|.:..|::.|....|.:|:|
plant   284 -CVSEV--------SGSFLKYIKGLKHLKTIWIDGAHVSDSSLVSLSSSCRSLMEIGLSRCVDVT 339

  Fly   338 --GMLSLTNELLLYVAGKWQSTLKVLDLMFCVQLNANCIDALRQLSGRLEALTMAYCRELTGTGL 400
              ||:||....|         .||.|:|..|..:....|.|:.|....|..|.:..|..:|..|
plant   340 DIGMISLARNCL---------NLKTLNLACCGFVTDVAISAVAQSCRNLGTLKLESCHLITEKG- 394

  Fly   401 LQGLAGDINYSLQELHLEETIFLDESSMCQLLERLPNLRRLSLDNCRQAVTDRTMATICQYQTRL 465
            ||.| |..:..:|||.|.:...:::..: :.:.:..||:||.|..|.. ::|:.:..|....::|
plant   395 LQSL-GCYSMLVQELDLTDCYGVNDRGL-EYISKCSNLQRLKLGLCTN-ISDKGIFHIGSKCSKL 456

  Fly   466 RNLNIEYCMKITDQGLMGYGDTPYPISRLRGLKELN---LRGCRNVTDSSLMVGLKLPELRALSL 527
            ..|::..|....|.||....         ||.|.||   |..|..:||:.:....:|..|..|.|
plant   457 LELDLYRCAGFGDDGLAALS---------RGCKSLNRLILSYCCELTDTGVEQIRQLELLSHLEL 512

  Fly   528 GYCNRLTSEGFEALTQNCPSLEALCVSSCMAVDDETVLNIVSNLKRLRVLNLSNC----TKLTLQ 588
            .....:|..|..|:...|..|..|.|..|..:||.....:....|.||.:||.||    |.|.:.
plant   513 RGLKNITGVGLAAIASGCKKLGYLDVKLCENIDDSGFWALAYFSKNLRQINLCNCSVSDTALCML 577

  Fly   589 SIHHILAHGHNLVQLIACSIDGMDHEQAQRILESQRPQMKQVLLXQERYI 638
            ..:.......:||.|...:::|.  |.|.|...::..::|  || ..|::
plant   578 MSNLSRVQDVDLVHLSRVTVEGF--EFALRACCNRLKKLK--LLAPLRFL 623

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12402	NP_001303481.1	F-box	75..117	CDD:279040
		leucine-rich repeat	281..303	CDD:275381	0/21 (0%)
		LRR_RI	<297..482	CDD:238064	50/190 (26%)
		leucine-rich repeat	304..330	CDD:275381	8/29 (28%)
		leucine-rich repeat	331..357	CDD:275381	8/27 (30%)
		leucine-rich repeat	358..379	CDD:275381	7/20 (35%)
		leucine-rich repeat	384..409	CDD:275381	9/24 (38%)
		leucine-rich repeat	412..437	CDD:275381	4/24 (17%)
		AMN1	430..595	CDD:187754	46/171 (27%)
		leucine-rich repeat	438..464	CDD:275381	7/25 (28%)
		leucine-rich repeat	465..496	CDD:275381	6/30 (20%)
		leucine-rich repeat	497..521	CDD:275381	8/26 (31%)
		leucine-rich repeat	522..547	CDD:275381	7/24 (29%)
		leucine-rich repeat	548..573	CDD:275381	6/24 (25%)
		leucine-rich repeat	574..599	CDD:275381	8/28 (29%)
AT5G27920	NP_568502.1	AMN1	65..261	CDD:187754	15/79 (19%)
		leucine-rich repeat	67..96	CDD:275381
		leucine-rich repeat	97..122	CDD:275381
		leucine-rich repeat	123..147	CDD:275381
		leucine-rich repeat	148..173	CDD:275381
		leucine-rich repeat	174..199	CDD:275381	1/1 (100%)
		AMN1	192..393	CDD:187754	53/256 (21%)
		leucine-rich repeat	200..222	CDD:275381	4/29 (14%)
		leucine-rich repeat	224..249	CDD:275381	6/24 (25%)
		leucine-rich repeat	250..298	CDD:275381	13/91 (14%)
		leucine-rich repeat	299..352	CDD:275381	16/61 (26%)
		AMN1	<329..464	CDD:187754	40/147 (27%)
		leucine-rich repeat	353..378	CDD:275381	8/24 (33%)
		leucine-rich repeat	379..404	CDD:275381	9/26 (35%)
		AMN1	405..>567	CDD:187754	46/172 (27%)
		leucine-rich repeat	405..429	CDD:275381	4/24 (17%)
		leucine-rich repeat	430..455	CDD:275381	7/25 (28%)
		leucine-rich repeat	456..481	CDD:275381	8/33 (24%)
		leucine-rich repeat	482..506	CDD:275381	7/23 (30%)
		leucine-rich repeat	507..532	CDD:275381	7/24 (29%)
		leucine-rich repeat	533..558	CDD:275381	6/24 (25%)
		leucine-rich repeat	559..583	CDD:275381	8/23 (35%)
		leucine-rich repeat	584..609	CDD:275381	7/26 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1947
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR13318
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910