Protein Alignment CG12402 and fbxl16

DIOPT Version :9

• Sequence 1: NP_001303481.1
• Gene: CG12402 / 41714
• FlyBaseID: FBgn0038202
• Length: 671
• Species: Drosophila melanogaster
• Sequence 2: NP_001188265.1
• Gene: fbxl16 / 797939
• ZFINID: ZDB-GENE-120215-180
• Length: 493
• Species: Danio rerio
• Alignment Length: 621
• Identity: 133/621 - (21%)
• Similarity: 213/621 - (34%)
• Gaps: 196/621 - (31%)

  Fly     1 MGNSLITSGKPSQRREKRLFERLSCSYAQTPNRMELNLNPLLAIARSIAAPPTPPPTPEKLDSDK 65
            :|::.||.|.|:.:  .||.:..|......|..:..:|:| |..|.|:..|          |.|.
Zfish    36 LGSASITKGTPAAK--NRLCQSSSVPTILPPPSLPYHLDP-LPTAASLLGP----------DLDT 87

  Fly    66 DKEGSSKAAIELLPNEMWLE---IMSYLSYNDLLQLRMVSWRC---------RDLVHRRRFMEKG 118
            ....:.|..:...|..: ||   |:.....|.||.....:.:|         |.::::.:|.|..
Zfish    88 SPVTAIKPPLRQFPKPL-LERQLILDEKVLNRLLWYFTTAEKCILAQVCKTWRKVLYQPKFWEGV 151

  Fly   119 KVIVTQHNLEAIHKHAK--------GGNCYLSFERIELRNLRQ-CRQLENFLRLVGHEVKHLQVR 174
            ..|:          |||        |...::|.:...||..:. |        |||
Zfish   152 TPIL----------HAKELYTILPNGEKEFVSLQAFALRGFQAFC--------LVG--------- 189

  Fly   175 HAPVFRNLDGKLPNLKVLTIATTMSMDDQHLAAMDDLDMKQFSHLVGFECDGVSLDAVLKMRMLL 239
                                             :.|||:.:|       .|...|.
Zfish   190 ---------------------------------VSDLDICEF-------IDNYPLS--------- 205

  Fly   240 QLRRTENKVQLRHLQFEFRRNNENALLDVLQDHAETLVCVNLFFSCSPGIDTREWCRAFENMHNL 304
              ::....|.|:      |....:|.|:|:                            .|.|..|
Zfish   206 --KKGVKSVSLK------RSTITDAGLEVM----------------------------LEQMQGL 234

  Fly   305 RTLKLSGNCHLVLLEAVLRAVPESAPIRQLDLTGMLSLTNELLLYVAGKWQS---TLKVLDLMFC 366
            ..|:||| |:                    |.|            .||.|.|   .|..|.:..|
Zfish   235 MHLELSG-CN--------------------DFT------------EAGLWSSLNARLTSLSVSDC 266

  Fly   367 VQLNANCIDALRQLSGRLEALTM-AYCRELTGTGLLQGLAGDINYSLQELHLEETIFLDESSMCQ 430
            :.:..:.|.|:.||...|..|:: ||  .:|.|.:....|.. .|:...|.|.....:....:..
Zfish   267 INVADDAIAAISQLLPNLSELSLQAY--HVTDTAMAYFTAKQ-GYTTHTLRLNSCWEITNHGVVN 328

  Fly   431 LLERLPNLRRLSLDNCRQAVTDRTMATICQYQTRLRNLNIEYCMKITDQGLMGYGDTPYPISRLR 495
            ::..||||..|||..|.: :||..:..:.:...:||:|::.:|.:|||..|      .|....|.
Zfish   329 MVHSLPNLTSLSLSGCSK-ITDDGVELVAENLRKLRSLDLSWCPRITDMAL------EYIACDLH 386

  Fly   496 GLKELNLRGCRNVTDSSLMVGLKLPELRALSLGYCNRLTSEGFEALTQNCPSLEALCVSSCMAVD 560
            .|:||.|..|..:||:.|.....:..||:|.|.:|.::...|.:.| ....||..|.::.|..:
Zfish   387 KLEELVLDRCVRITDTGLGYLSTMSTLRSLYLRWCCQVQDFGLQHL-YGMRSLRLLSLAGCPLL- 449

  Fly   561 DETVLNIVSNLKRLRVLNLSNCTKLTLQSIHHILAH 596
            ..|.|:.:..|:.|..|.|:||...|.:...:...|
Zfish   450 TTTGLSGLIQLQDLEELELTNCPGATAELFKYYSQH 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12402	NP_001303481.1	F-box	75..117	CDD:279040	10/53 (19%)
		leucine-rich repeat	281..303	CDD:275381	2/21 (10%)
		LRR_RI	<297..482	CDD:238064	48/188 (26%)
		leucine-rich repeat	304..330	CDD:275381	6/25 (24%)
		leucine-rich repeat	331..357	CDD:275381	6/28 (21%)
		leucine-rich repeat	358..379	CDD:275381	5/20 (25%)
		leucine-rich repeat	384..409	CDD:275381	7/25 (28%)
		leucine-rich repeat	412..437	CDD:275381	3/24 (13%)
		AMN1	430..595	CDD:187754	48/164 (29%)
		leucine-rich repeat	438..464	CDD:275381	7/25 (28%)
		leucine-rich repeat	465..496	CDD:275381	10/30 (33%)
		leucine-rich repeat	497..521	CDD:275381	8/23 (35%)
		leucine-rich repeat	522..547	CDD:275381	7/24 (29%)
		leucine-rich repeat	548..573	CDD:275381	6/24 (25%)
		leucine-rich repeat	574..599	CDD:275381	7/23 (30%)
fbxl16	NP_001188265.1	leucine-rich repeat	209..233	CDD:275381	8/57 (14%)
		AMN1	215..446	CDD:187754	73/308 (24%)
		leucine-rich repeat	234..253	CDD:275381	11/51 (22%)
		leucine-rich repeat	258..283	CDD:275381	7/24 (29%)
		leucine-rich repeat	284..308	CDD:275381	7/26 (27%)
		leucine-rich repeat	309..335	CDD:275381	3/25 (12%)
		leucine-rich repeat	336..361	CDD:275381	7/25 (28%)
		leucine-rich repeat	362..387	CDD:275381	10/30 (33%)
		leucine-rich repeat	388..412	CDD:275381	8/23 (35%)
		leucine-rich repeat	413..437	CDD:275381	7/24 (29%)
		leucine-rich repeat	438..457	CDD:275381	5/19 (26%)
		leucine-rich repeat	463..488	CDD:275381	7/23 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910