DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG12402 and Fbxl22

DIOPT Version :9

Sequence 1:NP_001303481.1 Gene:CG12402 / 41714 FlyBaseID:FBgn0038202 Length:671 Species:Drosophila melanogaster
Sequence 2:NP_780415.1 Gene:Fbxl22 / 74165 MGIID:1921415 Length:236 Species:Mus musculus


Alignment Length:291 Identity:61/291 - (20%)
Similarity:104/291 - (35%) Gaps:104/291 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly   364 MFCVQLNANCI---------DALRQLSGRLEALTMAYCRELTGTGLLQGLAGDINYSLQELHLEE 419
            |...|||..|:         |:.|.||        ..|.:|.          |:           
Mouse     1 MHITQLNRECLLCLFSFLDKDSRRSLS--------RTCSQLR----------DV----------- 36

  Fly   420 TIFLDESSMCQLLERLPNLRRLSLDNCRQAVTDRTMATICQYQTRLRNLNIEYCMKITDQGLMGY 484
               .::.::..|| ...:|..|..||.|.:...|:: :||.:.:|::..:||..:|...|..:  
Mouse    37 ---FEDPTLWPLL-HFHSLAELKKDNFRLSPALRSL-SICWHSSRVQVCSIEDWLKSALQRSI-- 94

  Fly   485 GDTPYPISRLRGLKELNLRGCRNVTDSSLMVGLKLPELRALSLGYCNRLTSEGFEALTQNCPSLE 549
                  .|:...|          |.|..|.|              |||            ||:|.
Mouse    95 ------CSQHESL----------VNDFLLQV--------------CNR------------CPNLT 117

  Fly   550 ALCVSSCMAVDDETVLNIVSNLKRLRVLNLSNCTKLTLQSIHHILAHGHNLVQL----------- 603
            ::.:|.|..|.|:.:..::.:..|||.|.|.||.::|.:::..:.|||..|..|           
Mouse   118 SVTLSGCGHVTDDCLARLLLSCPRLRTLRLENCARVTNRTLAAVAAHGRALQTLHVDFCRNVSAA 182

  Fly   604 ------IACSIDGMDHEQAQRILESQRPQMK 628
                  .||....:..|::..::..|.|:.:
Mouse   183 GLLRLRAACPNLRLSAERSAAMIPDQPPRAR 213

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG12402NP_001303481.1 F-box 75..117 CDD:279040
leucine-rich repeat 281..303 CDD:275381
LRR_RI <297..482 CDD:238064 27/126 (21%)
leucine-rich repeat 304..330 CDD:275381
leucine-rich repeat 331..357 CDD:275381
leucine-rich repeat 358..379 CDD:275381 6/23 (26%)
leucine-rich repeat 384..409 CDD:275381 3/24 (13%)
leucine-rich repeat 412..437 CDD:275381 2/24 (8%)
AMN1 430..595 CDD:187754 39/164 (24%)
leucine-rich repeat 438..464 CDD:275381 8/25 (32%)
leucine-rich repeat 465..496 CDD:275381 5/30 (17%)
leucine-rich repeat 497..521 CDD:275381 5/23 (22%)
leucine-rich repeat 522..547 CDD:275381 4/24 (17%)
leucine-rich repeat 548..573 CDD:275381 5/24 (21%)
leucine-rich repeat 574..599 CDD:275381 10/24 (42%)
Fbxl22NP_780415.1 F-box-like 3..43 CDD:403981 11/71 (15%)
LRR 1 15..40 7/56 (13%)
LRR 2 43..72 9/30 (30%)
AMN1 45..>200 CDD:187754 46/200 (23%)
LRR 3 98..123 11/60 (18%)
leucine-rich repeat 116..141 CDD:275381 5/24 (21%)
LRR 4 124..149 8/24 (33%)
leucine-rich repeat 142..167 CDD:275381 10/24 (42%)
LRR 5 150..175 7/24 (29%)
leucine-rich repeat 168..193 CDD:275381 4/24 (17%)
LRR 6 176..201 3/24 (13%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1947
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.