Protein Alignment CG12402 and Fbxo39

DIOPT Version :9

• Sequence 1: NP_001303481.1
• Gene: CG12402 / 41714
• FlyBaseID: FBgn0038202
• Length: 671
• Species: Drosophila melanogaster
• Sequence 2: XP_006533964.2
• Gene: Fbxo39 / 628100
• MGIID: 3505735
• Length: 480
• Species: Mus musculus
• Alignment Length: 466
• Identity: 99/466 - (21%)
• Similarity: 166/466 - (35%)
• Gaps: 120/466 - (25%)

  Fly    64 DKDKEGSSKAAIELLPNEMWLEIMSYLSYN-DLLQLRMVSWRCR-DLVHRRRFMEKGKVIVTQHN 126
            |:|:   |:||   |....|.:||    |: ||.:.|.:::..| ..||...| |.....:.:..
Mouse    70 DRDR---SRAA---LVCRKWNQIM----YSADLWRYRTITFSGRPSRVHASEF-ESALWYIKKFG 123

  Fly   127 LEAIHKHAKGGNCY-----LSFERIELRNLRQCRQLENFLRLVGHEVKHLQVRHAPVFRN-LDGK 185
            ....|...|..|.|     ..|: :.:|.|..|....| .||....::||::... |:|| :.|.
Mouse   124 RYLEHLEIKFLNPYNAVLTKKFQ-VTMRGLLSCLGKSN-NRLRSLSIQHLELDRL-VWRNSIRGS 185

  Fly   186 LPNLKVLTIATTMSMDDQHLAAMDDLDMK-------QFSHLVGFECDGVSLDAVLKMRMLLQLRR 243
            |    :.:::..:....:||   |.|.:|       |..|::.      ||..:....|..:|..
Mouse   186 L----IKSLSFFLKKMGKHL---DHLSLKGARLTVEQGCHILN------SLSYMQNENMASELNI 237

  Fly   244 TE--------------NKVQLRHLQFEFRRNNENALLDVL-----QDHAETLVCVNLFFSC---- 285
            .:              ||.........|...|.|.:.|.|     :::|.||..:|:  .|
Mouse   238 EDFFSHHLAVYGSSQFNKAMATFRNLTFLTLNYNCISDELLETLSENNAGTLRTMNI--KCHVHD 300

  Fly   286 --SPGIDTREWCRAFENMHNL-------RTLKLSGNCHLVLLEAVLRAVPESAPIRQLDLT---- 337
              ...:....|.:......||       |.:|         .|.:.|.:.:..|:|.:.|.
Mouse   301 PHGQVVWGMSWAKLARQASNLKVNFFFERVMK---------YERLARILLQEIPVRSISLRSCYF 356

  Fly   338 -----GMLSLTNELLLYVAGKWQSTLKVLDLMFCVQLNANCIDALRQLSGRLEALTMAYCRELTG 397
                 .|.....:||    ..:::||:.|...|    |.|    ...|..:|..|.:| ||:|..
Mouse   357 SDPDWSMRPTLTDLL----PTFRNTLQKLTFEF----NNN----HESLDEQLHLLILA-CRKLFY 408

  Fly   398 TGLLQGLAGDINYSLQELHLEETIFLDESSMCQLLERLPNLR-RLSLDNCRQAVTDRTMATICQY 461
            ..:...|  |:.:      :|..:...|...|.    |..|: |:..:.......|||:..|.:.
Mouse   409 FKIWAFL--DVKF------VERILKSQEEGQCS----LHTLKVRIYTNRYETNEEDRTLREIYRK 461

  Fly   462 QTRLRNLNIEY 472
            ..:|.:..:.|
Mouse   462 YRKLIDSELNY 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12402	NP_001303481.1	F-box	75..117	CDD:279040	12/43 (28%)
		leucine-rich repeat	281..303	CDD:275381	2/27 (7%)
		LRR_RI	<297..482	CDD:238064	39/193 (20%)
		leucine-rich repeat	304..330	CDD:275381	5/32 (16%)
		leucine-rich repeat	331..357	CDD:275381	5/34 (15%)
		leucine-rich repeat	358..379	CDD:275381	5/20 (25%)
		leucine-rich repeat	384..409	CDD:275381	8/24 (33%)
		leucine-rich repeat	412..437	CDD:275381	4/24 (17%)
		AMN1	430..595	CDD:187754	9/44 (20%)
		leucine-rich repeat	438..464	CDD:275381	6/26 (23%)
		leucine-rich repeat	465..496	CDD:275381	2/8 (25%)
		leucine-rich repeat	497..521	CDD:275381
		leucine-rich repeat	522..547	CDD:275381
		leucine-rich repeat	548..573	CDD:275381
		leucine-rich repeat	574..599	CDD:275381
Fbxo39	XP_006533964.2	F-box-like	53..94	CDD:372399	12/33 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1947
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900