DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG12402 and fbxl7

DIOPT Version :9

Sequence 1:NP_001303481.1 Gene:CG12402 / 41714 FlyBaseID:FBgn0038202 Length:671 Species:Drosophila melanogaster
Sequence 2:NP_001073511.1 Gene:fbxl7 / 569430 ZFINID:ZDB-GENE-061215-122 Length:489 Species:Danio rerio


Alignment Length:403 Identity:101/403 - (25%)
Similarity:176/403 - (43%) Gaps:77/403 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly   250 LRHLQFEFR--RNNENALLDVLQDHAETLVCVNLFFSCSPGIDTREWC---RAFENMHNL----- 304
            |.|.|...|  |:.:.|.:|:|.|||        |......:.|.:.|   |.....:||     
Zfish    94 LTHPQRCLRQPRDQQGAPVDILPDHA--------FLQIFTHLPTNQLCRCARVCRRWYNLAWDPR 150

  Fly   305 --RTLKLSGN----------------------CHLV----------LLEAVLRAVPESAP-IRQL 334
              ||::|:|:                      |..|          |.:..|..|.:|.| :|:|
Zfish   151 LWRTIRLTGDVLHVDRALRVLTRRLCQDTPNVCLTVETVMVSGCRRLTDRGLYTVAQSCPELRRL 215

  Fly   335 DLTGMLSLTNELLLYVAGKWQSTLKVLDLMFCVQLNANCIDALRQLSGRLEA----------LTM 389
            ::.|..:::||.:..|..:..: |:.||:..|.::  .||...|.:|.:|..          |.|
Zfish   216 EVAGCYNVSNEAVFEVVSRCPN-LEHLDVSGCSKV--TCISLTRDVSVKLSPLHGQQISIRFLDM 277

  Fly   390 AYCRELTGTGLLQGLAGDINYSLQELHLEETIFLDESSMCQLLERLPNLRRLSLDNCRQAVTDRT 454
            ..|..|...| |..:|.... .|..|:|...:.|.:..:..|:...|.:|.||:.:|| .::|..
Zfish   278 TDCFALEDEG-LHTIAAHCT-QLTHLYLRRCVRLTDEGLRFLVIYCPGVRELSVSDCR-FISDFG 339

  Fly   455 MATICQYQTRLRNLNIEYCMKITDQGLMGYGDTPYPISRLRGLKELNLRGCRNVTDSSL-MVGLK 518
            :..|.:.:.|||.|:|.:|.:|||.|:.      |.......|:.||.|||..:||..: .:...
Zfish   340 LREIAKLEGRLRYLSIAHCSRITDVGVR------YVAKYCSRLRYLNARGCEGLTDHGIEHLAKS 398

  Fly   519 LPELRALSLGYCNRLTSEGFEALTQNCPSLEALCVSSCMAVDDETVLNIVSNLKRLRVLNLSNCT 583
            ..:|::|.:|.|..::..|.|.|..|..:|:.|.:.||.::....:..:.:|...|::||:.:| 
Zfish   399 CLKLKSLDIGKCPLVSDAGLEQLALNSFNLKRLSLKSCESITGRGLQVVAANCFDLQLLNVQDC- 462

  Fly   584 KLTLQSIHHILAH 596
            .::|:::..:..|
Zfish   463 DVSLEALRFVKRH 475

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG12402NP_001303481.1 F-box 75..117 CDD:279040
leucine-rich repeat 281..303 CDD:275381 4/24 (17%)
LRR_RI <297..482 CDD:238064 58/234 (25%)
leucine-rich repeat 304..330 CDD:275381 11/64 (17%)
leucine-rich repeat 331..357 CDD:275381 6/25 (24%)
leucine-rich repeat 358..379 CDD:275381 6/20 (30%)
leucine-rich repeat 384..409 CDD:275381 8/34 (24%)
leucine-rich repeat 412..437 CDD:275381 5/24 (21%)
AMN1 430..595 CDD:187754 46/165 (28%)
leucine-rich repeat 438..464 CDD:275381 7/25 (28%)
leucine-rich repeat 465..496 CDD:275381 10/30 (33%)
leucine-rich repeat 497..521 CDD:275381 8/24 (33%)
leucine-rich repeat 522..547 CDD:275381 8/24 (33%)
leucine-rich repeat 548..573 CDD:275381 5/24 (21%)
leucine-rich repeat 574..599 CDD:275381 6/23 (26%)
fbxl7NP_001073511.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..76
F-box-like 112..158 CDD:289689 13/53 (25%)
leucine-rich repeat 127..151 CDD:275381 5/23 (22%)
leucine-rich repeat 152..185 CDD:275381 5/32 (16%)
LRR 1 168..193 2/24 (8%)
AMN1 <183..364 CDD:187754 50/186 (27%)
leucine-rich repeat 186..211 CDD:275381 5/24 (21%)
LRR 2 194..219 7/24 (29%)
leucine-rich repeat 212..233 CDD:275381 6/20 (30%)
LRR 3 220..245 6/25 (24%)
leucine-rich repeat 238..271 CDD:275381 9/34 (26%)
LRR 4 251..279 7/27 (26%)
leucine-rich repeat 272..297 CDD:275381 7/26 (27%)
LRR 5 280..305 8/26 (31%)
AMN1 295..463 CDD:187754 49/176 (28%)
leucine-rich repeat 298..323 CDD:275381 5/24 (21%)
LRR 6 306..331 6/24 (25%)
leucine-rich repeat 324..349 CDD:275381 7/25 (28%)
LRR 7 332..357 9/25 (36%)
leucine-rich repeat 350..375 CDD:275381 10/30 (33%)
LRR 8 358..383 9/30 (30%)
leucine-rich repeat 376..401 CDD:275381 8/24 (33%)
LRR 9 384..409 5/24 (21%)
leucine-rich repeat 402..427 CDD:275381 8/24 (33%)
LRR 10 410..435 7/24 (29%)
leucine-rich repeat 428..451 CDD:275381 4/22 (18%)
LRR 11 436..461 5/24 (21%)
leucine-rich repeat 454..478 CDD:275381 6/23 (26%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1947
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
32.810

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