DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG12402 and Fbxl16

DIOPT Version :9

Sequence 1:NP_001303481.1 Gene:CG12402 / 41714 FlyBaseID:FBgn0038202 Length:671 Species:Drosophila melanogaster
Sequence 2:XP_038942467.1 Gene:Fbxl16 / 494223 RGDID:1309127 Length:488 Species:Rattus norvegicus


Alignment Length:333 Identity:85/333 - (25%)
Similarity:143/333 - (42%) Gaps:63/333 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly   285 CSPGIDTREWCRAFEN----MHNLRTLKLSGNCHLVLLEAVLRAVPESAP-IRQLDLTGMLSLTN 344
            |..|:...:.|...:|    ...::.:.|..:   .:.:|.|..:.|... :.:|:|:|....|.
  Rat   172 CLVGVSDLDICEFIDNYSLSKKGVKAMSLKRS---TITDAGLEVMLEQMQGVVRLELSGCNDFTE 233

  Fly   345 ELLLYVAGKWQS------TLKVLDLMFCVQLNANCIDALRQLSGRLEALTM-AYCRELTGTGLLQ 402
                  ||.|.|      :|.|.|   |:.:..:.|.|:.||...|..|:: ||  .:|.|.|..
  Rat   234 ------AGLWSSLSARITSLSVSD---CINVADDAIAAISQLLPNLAELSLQAY--HVTDTALAY 287

  Fly   403 GLA--GDINYSLQELHLEETIFLDESSMCQLLERLPNLRRLSLDNCRQAVTDRTMATICQYQTRL 465
            ..|  |...::|:.|...|   :....:..::..||||..|||..|.: |||..:..:.:...:|
  Rat   288 FTARQGHSTHTLRLLSCWE---ITNHGVVNVVHSLPNLTSLSLSGCSK-VTDDGVELVAENLRKL 348

  Fly   466 RNLNIEYCMKITDQGLMGYGDTPYPISRLRGLKELNLRGCRNVTDSSLMVGLKLPELRALSLGYC 530
            |:|::.:|.:|||..|      .|....|..|:||.|..|.:                ..:.|:|
  Rat   349 RSLDLSWCPRITDMAL------EYVACDLHRLEELVLDRCTH----------------PYTPGWC 391

  Fly   531 NRLTSEGFEALTQNCPSLEALCVSSCMAVDDETVLNIVSNLKRLRVLNLSNCTKLTLQSIHHILA 595
            .|:|..|...|: ...||.:|.:..|..|.|..:.:::: ::.||:|:|:.|..||...:     
  Rat   392 VRITDTGLSYLS-TMSSLRSLYLRWCCQVQDFGLKHLLA-MRSLRLLSLAGCPLLTTTGL----- 449

  Fly   596 HGHNLVQL 603
              ..||||
  Rat   450 --SGLVQL 455

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG12402NP_001303481.1 F-box 75..117 CDD:279040
leucine-rich repeat 281..303 CDD:275381 4/21 (19%)
LRR_RI <297..482 CDD:238064 51/198 (26%)
leucine-rich repeat 304..330 CDD:275381 4/25 (16%)
leucine-rich repeat 331..357 CDD:275381 8/31 (26%)
leucine-rich repeat 358..379 CDD:275381 6/20 (30%)
leucine-rich repeat 384..409 CDD:275381 9/27 (33%)
leucine-rich repeat 412..437 CDD:275381 4/24 (17%)
AMN1 430..595 CDD:187754 45/164 (27%)
leucine-rich repeat 438..464 CDD:275381 8/25 (32%)
leucine-rich repeat 465..496 CDD:275381 10/30 (33%)
leucine-rich repeat 497..521 CDD:275381 5/23 (22%)
leucine-rich repeat 522..547 CDD:275381 6/24 (25%)
leucine-rich repeat 548..573 CDD:275381 5/24 (21%)
leucine-rich repeat 574..599 CDD:275381 7/24 (29%)
Fbxl16XP_038942467.1 leucine-rich repeat 195..219 CDD:275381 4/26 (15%)
AMN1 201..422 CDD:187754 68/261 (26%)
leucine-rich repeat 220..243 CDD:275381 8/28 (29%)
leucine-rich repeat 244..269 CDD:275381 8/27 (30%)
leucine-rich repeat 270..321 CDD:275381 13/55 (24%)
leucine-rich repeat 322..347 CDD:275381 8/25 (32%)
leucine-rich repeat 348..373 CDD:275381 10/30 (33%)
leucine-rich repeat 374..407 CDD:275381 11/49 (22%)
leucine-rich repeat 408..427 CDD:275381 5/18 (28%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1947
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.810

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