Protein Alignment CG12402 and Fbxl7

DIOPT Version :9

• Sequence 1: NP_001303481.1
• Gene: CG12402 / 41714
• FlyBaseID: FBgn0038202
• Length: 671
• Species: Drosophila melanogaster
• Sequence 2: NP_001102015.1
• Gene: Fbxl7 / 361907
• RGDID: 1305813
• Length: 491
• Species: Rattus norvegicus
• Alignment Length: 573
• Identity: 122/573 - (21%)
• Similarity: 214/573 - (37%)
• Gaps: 202/573 - (35%)

  Fly    47 SIAAPPTPPPTP-----EKLDSDKDKEGSSKAAIELLPNEMWLEIMSYLSYNDLLQLRMVSWRCR 106
            ::|...:||||.     .:|.|...||   :|:|:.||:...::|.|:|..|.|         ||
  Rat    84 TVAMVHSPPPTRLTHPLIRLASRPQKE---QASIDRLPDHSMVQIFSFLPTNQL---------CR 136

  Fly   107 DLVHRRRFMEKGKVIVTQHNLEAIHKHAKGGNCYLSFERIELRNLRQCRQLENF---------LR 162
                                            |           .|.||:..|.         :|
  Rat   137 --------------------------------C-----------ARVCRRWYNLAWDPRLWRTIR 158

  Fly   163 LVGHEVKHLQVRHAPVFRNLDGKLPNLKVLTIATTMSMDDQHLAAMDDLDMKQFSHLVGFECDGV 227
            |.|..:            |:|..   |||||  ..:..|..::..|
  Rat   159 LTGETI------------NVDRA---LKVLT--RRLCQDTPNVCLM------------------- 187

  Fly   228 SLDAVLKMRMLLQLRRTENKVQLRHLQFEFRRNNENALLDVLQDHAETLVCVNLFFSCSPGIDTR 292
             |:.|:....                    ||..:..|..:.|              |.|
  Rat   188 -LETVIVSGC--------------------RRLTDRGLYTIAQ--------------CCP----- 212

  Fly   293 EWCRAFENMHNLRTLKLSGNCHLVLLEAVLRAVPESAPIRQLDLTG-----MLSLTNELLLYVA- 351
                      .||.|::|| |:.:..|||...|.....:..||::|     .:|||.|..:.::
  Rat   213 ----------ELRRLEVSG-CYNISNEAVFDVVSLCPNLEHLDVSGCSKVTCISLTREASIKLSP 266

  Fly   352 --GKWQSTLKVLDLMFCVQLNANCIDALRQLSGRLEALTMAYCRELTGTGLLQGLAGDINYSLQE 414
              || |.:::.||:..|..|....:..:           .|:|.:||                 .
  Rat   267 LHGK-QISIRYLDMTDCFVLEDEGLHTI-----------AAHCTQLT-----------------H 302

  Fly   415 LHLEETIFLDESSMCQLLERLPNLRRLSLDNCRQAVTDRTMATICQYQTRLRNLNIEYCMKITDQ 479
            |:|...:.|.:..:..|:....:::.||:.:|| .|:|..:..|.:.::|||.|:|.:|.:|||.
  Rat   303 LYLRRCVRLTDEGLRYLVIYCTSIKELSVSDCR-FVSDFGLREIAKLESRLRYLSIAHCGRITDV 366

  Fly   480 GLMGYGDTPYPISRLRGLKELNLRGCRNVTDSSL-MVGLKLPELRALSLGYCNRLTSEGFEALTQ 543
            |:.      |.......|:.||.|||..:||..: .:.....:|::|.:|.|..::..|.|:|..
  Rat   367 GIR------YVAKYCSKLRYLNARGCEGITDHGVEYLAKNCTKLKSLDIGKCPLVSDTGLESLAL 425

  Fly   544 NCPSLEALCVSSCMAVDDETVLNIVSNLKRLRVLNLSNCTKLTLQSIHHILAH 596
            ||.:|:.|.:.||.::..:.:..:.:|...|::||:.:| :::::::..:..|
  Rat   426 NCFNLKRLSLKSCESITGQGLQIVAANCFDLQMLNVQDC-EVSVEALRFVKRH 477

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12402	NP_001303481.1	F-box	75..117	CDD:279040	10/41 (24%)
		leucine-rich repeat	281..303	CDD:275381	2/21 (10%)
		LRR_RI	<297..482	CDD:238064	49/192 (26%)
		leucine-rich repeat	304..330	CDD:275381	10/25 (40%)
		leucine-rich repeat	331..357	CDD:275381	10/33 (30%)
		leucine-rich repeat	358..379	CDD:275381	4/20 (20%)
		leucine-rich repeat	384..409	CDD:275381	4/24 (17%)
		leucine-rich repeat	412..437	CDD:275381	4/24 (17%)
		AMN1	430..595	CDD:187754	45/165 (27%)
		leucine-rich repeat	438..464	CDD:275381	7/25 (28%)
		leucine-rich repeat	465..496	CDD:275381	10/30 (33%)
		leucine-rich repeat	497..521	CDD:275381	8/24 (33%)
		leucine-rich repeat	522..547	CDD:275381	9/24 (38%)
		leucine-rich repeat	548..573	CDD:275381	5/24 (21%)
		leucine-rich repeat	574..599	CDD:275381	5/23 (22%)
Fbxl7	NP_001102015.1	F-box-like	114..160	CDD:289689	16/97 (16%)
		leucine-rich repeat	129..151	CDD:275381	10/73 (14%)
		leucine-rich repeat	154..187	CDD:275381	11/49 (22%)
		AMN1	<185..366	CDD:187754	56/280 (20%)
		leucine-rich repeat	188..213	CDD:275381	8/73 (11%)
		leucine-rich repeat	214..234	CDD:275381	9/20 (45%)
		leucine-rich repeat	240..273	CDD:275381	10/33 (30%)
		leucine-rich repeat	274..299	CDD:275381	6/35 (17%)
		AMN1	297..464	CDD:187754	50/190 (26%)
		leucine-rich repeat	300..325	CDD:275381	6/41 (15%)
		leucine-rich repeat	326..351	CDD:275381	7/25 (28%)
		leucine-rich repeat	352..377	CDD:275381	10/30 (33%)
		leucine-rich repeat	378..403	CDD:275381	8/24 (33%)
		leucine-rich repeat	404..429	CDD:275381	9/24 (38%)
		leucine-rich repeat	430..453	CDD:275381	4/22 (18%)
		leucine-rich repeat	456..480	CDD:275381	5/23 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910