DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG12402 and fbxl-1

DIOPT Version :9

Sequence 1:NP_001303481.1 Gene:CG12402 / 41714 FlyBaseID:FBgn0038202 Length:671 Species:Drosophila melanogaster
Sequence 2:NP_741248.1 Gene:fbxl-1 / 3564805 WormBaseID:WBGene00015350 Length:466 Species:Caenorhabditis elegans


Alignment Length:448 Identity:105/448 - (23%)
Similarity:178/448 - (39%) Gaps:95/448 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly   236 RMLLQLRRTENKVQLRHLQFEF-----RRNNENALLD-VLQDHAETLVCVNLFFSCSPGIDTREW 294
            |:..|..:|...:|.:..|...     ....:|:|:: ||.  .|.|:.|..|      :||:..
 Worm    21 RLAQQAHKTHPVIQAKQNQMYLITTLSPAQVDNSLINRVLP--KEVLLKVFSF------LDTKAL 77

  Fly   295 CRAFENMHNLRTLKLSG-NCHLVLLEAVLRAVPESAPIRQLDLTGMLSLTNELLLYVAGKWQSTL 358
            ||:.:...:...|.|.| |...|.|....|.| ::|.:..|                |.:....|
 Worm    78 CRSAQVCRSWSILALDGSNWQRVDLFTFQRDV-KTAVVENL----------------ARRCGGFL 125

  Fly   359 KVLDLMFCVQLNANCIDALRQLSGR---LEALTMAYCRELTGTGLLQGLAGDINYSLQELHLEET 420
            |.|.|..|..::.:   |||..:.|   ||.|::..|:.:|... .:.| |...:.|..|:||..
 Worm   126 KELSLKGCENVHDS---ALRTFTSRCPNLEHLSLYRCKRVTDAS-CENL-GRYCHKLNYLNLENC 185

  Fly   421 IFLDESSMCQLLERLPNLRRLS---------------LDNCR----------QAVTDRTMATICQ 460
            ..:.:.:|..:.:..|||..|:               |.||:          :.:|:....::..
 Worm   186 SSITDRAMKYIGDGCPNLSYLNISWCDAIQDRGVQIILSNCKSLDTLILRGCEGLTENVFGSVEA 250

  Fly   461 YQTRLRNLNIEYCMKITD---QGLMGYGDTPYPISRLRGLKELNLRGCRNVTDSSLM-VGLKLPE 521
            :...::.||:..|.::||   |.:.. |.|        .|:.|.:..|..::|.||: :|.....
 Worm   251 HMGAIKKLNLLQCFQLTDITVQNIAN-GAT--------ALEYLCMSNCNQISDRSLVSLGQHSHN 306

  Fly   522 LRALSLGYCNRLTSEGFEALTQNCPSLEALCVSSCMAVDDETVLNIVSNLKRLRVLNLSNCTKLT 586
            |:.|.|..|..|...||..|.:.|..||.|.:..|..:.|.|:.::.:|...||.|:||:|..:|
 Worm   307 LKVLELSGCTLLGDNGFIPLARGCRQLERLDMEDCSLISDHTINSLANNCTALRELSLSHCELIT 371

  Fly   587 LQSIHHILAHGHNLVQLIACSIDGMDHEQAQRILESQR-PQMKQVLLXQERYIHXRSR 643
            .:||.::.:                .|.:...:||... ||:....|...|:.....|
 Worm   372 DESIQNLAS----------------KHRETLNVLELDNCPQLTDSTLSHLRHCKALKR 413

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG12402NP_001303481.1 F-box 75..117 CDD:279040
leucine-rich repeat 281..303 CDD:275381 5/21 (24%)
LRR_RI <297..482 CDD:238064 46/216 (21%)
leucine-rich repeat 304..330 CDD:275381 8/26 (31%)
leucine-rich repeat 331..357 CDD:275381 2/25 (8%)
leucine-rich repeat 358..379 CDD:275381 7/20 (35%)
leucine-rich repeat 384..409 CDD:275381 7/24 (29%)
leucine-rich repeat 412..437 CDD:275381 5/24 (21%)
AMN1 430..595 CDD:187754 48/193 (25%)
leucine-rich repeat 438..464 CDD:275381 6/50 (12%)
leucine-rich repeat 465..496 CDD:275381 8/33 (24%)
leucine-rich repeat 497..521 CDD:275381 7/24 (29%)
leucine-rich repeat 522..547 CDD:275381 9/24 (38%)
leucine-rich repeat 548..573 CDD:275381 7/24 (29%)
leucine-rich repeat 574..599 CDD:275381 9/24 (38%)
fbxl-1NP_741248.1 F-box-like 60..101 CDD:372399 13/48 (27%)
AMN1 <121..268 CDD:187754 32/151 (21%)
leucine-rich repeat 125..150 CDD:275381 9/27 (33%)
leucine-rich repeat 151..176 CDD:275381 7/26 (27%)
leucine-rich repeat 177..202 CDD:275381 5/24 (21%)
leucine-rich repeat 203..228 CDD:275381 5/24 (21%)
leucine-rich repeat 229..280 CDD:275381 9/59 (15%)
AMN1 <281..440 CDD:187754 40/149 (27%)
leucine-rich repeat 281..306 CDD:275381 7/24 (29%)
leucine-rich repeat 307..332 CDD:275381 9/24 (38%)
leucine-rich repeat 333..357 CDD:275381 7/23 (30%)
leucine-rich repeat 359..384 CDD:275381 10/40 (25%)
leucine-rich repeat 386..409 CDD:275381 6/22 (27%)
leucine-rich repeat 411..436 CDD:275381 1/3 (33%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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