DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG12402 and Fbxl13

DIOPT Version :9

Sequence 1:NP_001303481.1 Gene:CG12402 / 41714 FlyBaseID:FBgn0038202 Length:671 Species:Drosophila melanogaster
Sequence 2:XP_038962809.1 Gene:Fbxl13 / 100125363 RGDID:1642425 Length:823 Species:Rattus norvegicus


Alignment Length:658 Identity:134/658 - (20%)
Similarity:257/658 - (39%) Gaps:160/658 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly    75 IELLPNEMWLEIMSYLSYNDLLQLRMVS------------WRCRDLVHRRRFMEKGKVIVTQH-N 126
            |.:||::..::|..||::.||:....|:            |...|....:...::..|...|. .
  Rat   242 ISVLPDQAVVQIFVYLTFKDLVSCSQVNRSWMSMIQRGSLWNSIDFSTVKNIADRCVVTTLQKWR 306

  Fly   127 LEAIHKHAKGGNCYLSFERIELRNLRQCRQLENFLRLVGHEVKHLQVRHAPVF-----RNLDGKL 186
            |..:..:.:|  |.|..:  .|:::..|:.|:           .|.|...|.|     |::....
  Rat   307 LNVLRLNFRG--CVLRAK--TLKSVSHCKNLQ-----------ELNVSDCPSFTDESMRHISEGC 356

  Fly   187 P-----NLKVLTIAT-TMSMDDQHLAAMDDLDM---KQFS--------------HLVGFECDGVS 228
            |     ||...||.. ||.:..::...:.:|.:   ::|:              .|:..:..|.:
  Rat   357 PGVLYLNLSNTTITNRTMRLLPRYFHNLQNLSLAYCRKFTDKGLQYLNLGNGCHKLIYLDLSGCT 421

  Fly   229 LDAVLKMRMLLQLRRTENKVQLRHLQFEFRRNNENALLD----VLQDHAETLVCVNLFFSCSPGI 289
            ..:|...|.:     ..:...:.||..    |:...|.|    ||.:....:..|  .|..||.|
  Rat   422 QISVQGFRNI-----ANSCTGIMHLTI----NDMPTLTDNCVKVLVEKCPRISSV--VFIGSPHI 475

  Fly   290 DTREWCRAFENMH--NLRTLKLSGNCHLVLLEAVLRAVPESAP----IRQLDLTGMLSLTNELLL 348
            ..   | ||:.:.  :|:.::..||..:.  :|..::|..:.|    |..:|..|:.        
  Rat   476 SD---C-AFKALSACDLKKIRFEGNKRIT--DACFKSVDRNYPGISHIYMVDCKGLT-------- 526

  Fly   349 YVAGKWQSTLKVLDLMFCVQLNANCIDALRQLSGRLEALTMAYCRELTGTGLLQGLAGDINYSLQ 413
                  .|:||.|.:             |:||:    .|.:..|..:...||.|...|..:..|:
  Rat   527 ------DSSLKSLSV-------------LKQLT----VLNLTNCVRIGDIGLRQFFDGPASVKLR 568

  Fly   414 ELHLEETIFLDESSMCQLLERLPNLRRLSLDNCRQ-----------------------AVTDRTM 455
            ||:|.....|.::|:.:|.||.|||..|:|.||..                       .:::..:
  Rat   569 ELNLANCSLLGDTSVIRLSERCPNLHYLNLRNCEHLTDLAIEYIASMLSLISIDLSGTLISNEGL 633

  Fly   456 ATICQYQTRLRNLNIEYCMKITDQGLMGYGDTPYPISRLRGLKELNLRGCRNVTDSSL-MVGLKL 519
            |.:.::: :||.:::..|:.|||.|:..:..|..      .|:.|::..|..:||..: .:.:..
  Rat   634 AILSRHR-KLREVSLSECVNITDFGIRAFCKTSL------ALEHLDVSYCAQLTDDIIKTIAIFC 691

  Fly   520 PELRALSLGYCNRLTSEGFEALTQNCPSLEALCVSSCMAVDDETVLNIVSNLKRLRVLNLSNCTK 584
            ..:.:|.:..|.::|..|.|.|:..|..|..|.:|.|:.:.|:.:.::....|:||:|.:..|..
  Rat   692 TRITSLHIAGCPKITDGGMEILSARCHYLHILDISGCVQLTDQILQDLQIGCKQLRILKMQFCKS 756

  Fly   585 LTLQSIHHILAHGHNLVQLIACSID------GMDHEQAQRILESQRPQMK---QVLLXQERYIHX 640
            ::..:...:    .::||....|.:      |.|.|  ...||....::|   ::::.:......
  Rat   757 ISSAAAQKM----SSVVQQQEYSSESPPSWFGYDSE--GNPLEETHTKVKTYSEMIVKESLSSDD 815

  Fly   641 RSRNTPHH 648
            .:.|:.||
  Rat   816 ETPNSKHH 823

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG12402NP_001303481.1 F-box 75..117 CDD:279040 11/53 (21%)
leucine-rich repeat 281..303 CDD:275381 7/23 (30%)
LRR_RI <297..482 CDD:238064 48/213 (23%)
leucine-rich repeat 304..330 CDD:275381 5/25 (20%)
leucine-rich repeat 331..357 CDD:275381 3/25 (12%)
leucine-rich repeat 358..379 CDD:275381 4/20 (20%)
leucine-rich repeat 384..409 CDD:275381 6/24 (25%)
leucine-rich repeat 412..437 CDD:275381 9/24 (38%)
AMN1 430..595 CDD:187754 41/188 (22%)
leucine-rich repeat 438..464 CDD:275381 6/48 (13%)
leucine-rich repeat 465..496 CDD:275381 8/30 (27%)
leucine-rich repeat 497..521 CDD:275381 5/24 (21%)
leucine-rich repeat 522..547 CDD:275381 7/24 (29%)
leucine-rich repeat 548..573 CDD:275381 5/24 (21%)
leucine-rich repeat 574..599 CDD:275381 4/24 (17%)
Fbxl13XP_038962809.1 Sfi1 <134..>214 CDD:400658
F-box-like 242..286 CDD:403981 10/43 (23%)
leucine-rich repeat 257..270 CDD:275381 4/12 (33%)
leucine-rich repeat 282..308 CDD:275381 4/25 (16%)
AMN1 308..477 CDD:187754 36/194 (19%)
leucine-rich repeat 309..332 CDD:275381 5/26 (19%)
leucine-rich repeat 333..358 CDD:275381 6/35 (17%)
leucine-rich repeat 359..383 CDD:275381 6/23 (26%)
leucine-rich repeat 384..402 CDD:275381 2/17 (12%)
leucine-rich repeat 412..437 CDD:275381 4/29 (14%)
leucine-rich repeat 438..463 CDD:275381 7/28 (25%)
leucine-rich repeat 464..486 CDD:275381 8/27 (30%)
leucine-rich repeat 488..513 CDD:275381 5/26 (19%)
leucine-rich repeat 514..534 CDD:275381 6/33 (18%)
AMN1 525..733 CDD:187754 54/245 (22%)
leucine-rich repeat 539..563 CDD:275381 7/27 (26%)
leucine-rich repeat 567..592 CDD:275381 9/24 (38%)
leucine-rich repeat 593..617 CDD:275381 5/23 (22%)
leucine-rich repeat 618..641 CDD:275381 1/23 (4%)
leucine-rich repeat 642..667 CDD:275381 8/30 (27%)
leucine-rich repeat 668..693 CDD:275381 5/24 (21%)
leucine-rich repeat 694..719 CDD:275381 7/24 (29%)
leucine-rich repeat 720..745 CDD:275381 5/24 (21%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1947
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
21.900

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