DRSC/TRiP Functional Genomics Resources

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Protein Alignment PK1-R and Nmur2

DIOPT Version :9

Sequence 1:NP_001014620.1 Gene:PK1-R / 41713 FlyBaseID:FBgn0038201 Length:430 Species:Drosophila melanogaster
Sequence 2:NP_071611.3 Gene:Nmur2 / 64042 RGDID:621155 Length:395 Species:Rattus norvegicus


Alignment Length:367 Identity:118/367 - (32%)
Similarity:196/367 - (53%) Gaps:67/367 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly     6 MSHDLGPPRDPLAIVIPVTVVYSLIFITGVVGNISTCIVIKKNRSMHTATNYYLFSLAISDFLLL 70
            ::|..||.|..|:  :||:|.|:|||:.||:||:..|:||.:::::.|.|||||||||:||.|:|
  Rat    25 LAHLCGPKRSDLS--LPVSVAYALIFLVGVMGNLLVCMVIVRHQTLKTPTNYYLFSLAVSDLLVL 87

  Fly    71 LSGVPQEVSYIWSKYPYVFGEYICIGRGLLAETSANATVLTITAFTVERYIAICHPFLGQAMSKL 135
            |.|:|.|:..:|..||::||...|..:..|.||...|::|::|..:||||:||.|||..:..|..
  Rat    88 LLGMPLEIYEMWHNYPFLFGPVGCYFKTALFETVCFASILSVTTVSVERYVAIVHPFRAKLESTR 152

  Fly   136 SRAIRIIVLVWIMAIVTAIPQAAQFGI--EHY------SGVEQCGIVRVIVKHS--FQLSTFIFF 190
            .||:||:.|||..::|.::|..:..||  :|:      .|...|.:.:.:..::  .|.::|:|:
  Rat   153 RRALRILSLVWSFSVVFSLPNTSIHGIKFQHFPNGSSVPGSATCTVTKPMWVYNLIIQATSFLFY 217

  Fly   191 LAPMSIILVLYLLIGVHLYRSTLVEGPASVARRQQLKSVPSDTILYRYGGSGTAMSFNGGGSGAG 255
            :.||::|.|||.|:|:.|.|...:|.                                       
  Rat   218 ILPMTLISVLYYLMGLRLKRDESLEA--------------------------------------- 243

  Fly   256 TAGLMGGSGAQLSSVRGRLNHYGTRRVLRMLVAVVVCFFLCWAPFHAQRLIAIYAPARGAKLRDQ 320
                        :.|...::....:.|.:||..:|:.|.:||.|||..||...:.    .:..:.
  Rat   244 ------------NKVAVNIHRPSRKSVTKMLFVLVLVFAICWTPFHVDRLFFSFV----EEWTES 292

  Fly   321 HEFVYTVMTYVSGVLYYLSTCINPLLYNIMSHKFREAFKAVL 362
            ...|:.::..||||.:|||:.:||::||::|.:||.||:.|:
  Rat   293 LAAVFNLIHVVSGVFFYLSSAVNPIIYNLLSRRFRAAFRNVV 334

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PK1-RNP_001014620.1 7tmA_capaR 21..358 CDD:320262 110/346 (32%)
TM helix 1 21..48 CDD:320262 14/26 (54%)
TM helix 2 55..81 CDD:320262 17/25 (68%)
TM helix 3 94..124 CDD:320262 12/29 (41%)
TM helix 4 136..158 CDD:320262 9/21 (43%)
TM helix 5 178..207 CDD:320262 11/30 (37%)
TM helix 6 277..307 CDD:320262 12/29 (41%)
TM helix 7 326..351 CDD:320262 11/24 (46%)
Nmur2NP_071611.3 7tm_4 48..333 CDD:304433 106/339 (31%)
7tm_1 54..319 CDD:278431 96/319 (30%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 374..395
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C166338878
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E33208_3BGH7
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D380940at33208
OrthoFinder 1 1.000 - - FOG0001494
OrthoInspector 1 1.000 - - mtm8974
orthoMCL 1 0.900 - - OOG6_105236
Panther 1 1.100 - - O PTHR24243
Phylome 1 0.910 - -
SonicParanoid 1 1.000 - - X673
SwiftOrtho 1 1.000 - -
TreeFam 1 0.960 - -
1211.710

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