Protein Alignment PK1-R and nmur1b

DIOPT Version :10

• Sequence 1: NP_001014620.1
• Gene: PK1-R / 41713
• FlyBaseID: FBgn0038201
• Length: 430
• Species: Drosophila melanogaster
• Sequence 2: XP_698473.4
• Gene: nmur1b / 569960
• ZFINID: ZDB-GENE-131121-154
• Length: 404
• Species: Danio rerio
• Alignment Length: 419
• Identity: 148/419 - (35%)
• Similarity: 218/419 - (52%)
• Gaps: 80/419 - (19%)

  Fly    10 LGPPRDPLAIVIPVTVVYSLIFITGVVGNISTCIVIKKNRSMHTATNYYLFSLAISDFLLLLSGV 74
            |||.|.|  ..:|:.|.|.|||:.||||||.|||||.::|.|.|.||||||||||||.|:||.|:
Zfish    51 LGPCRSP--FFLPICVTYLLIFVVGVVGNILTCIVITRHRIMRTTTNYYLFSLAISDLLVLLLGL 113

  Fly    75 PQEVSYIWSKYPYVFGEYICIGRGLLAETSANATVLTITAFTVERYIAICHPFLGQAMSKLSRAI 139
            |.|:..:||.||::||...|..:..|.||...|:||.:||.:.|||.||.||...:.::..:.|.
Zfish   114 PLELYELWSNYPFLFGISGCYFKTCLFETVCFASVLNVTALSAERYRAIIHPLHTKHVATSAHAK 178

  Fly   140 RIIVLVWIMAIVTAIPQAAQFGIEHY----------SGVEQCGIV--RVIVKHSFQLSTFIFFLA 192
            |:|:::|.::::.|:|..:..|:|..          |||  |.:|  |.|.....|::..:||:.
Zfish   179 RVILVLWAVSLLCALPNTSIHGVEMLKPRFGLTFPESGV--CTVVHDRWIYNLLVQVTALLFFIL 241

  Fly   193 PMSIILVLYLLIGVHLYRSTLVEGPASVARRQQLKSVPSDTILYRYGGSGTAMSFNGGGSGAGTA 257
            ||..|.|||:|||:.|:|              :.:...|..:|.:.|
Zfish   242 PMLTISVLYVLIGLQLHR--------------ERECFDSKIVLNQDG------------------ 274

  Fly   258 GLMGGSGAQLSSVRGRLNHYGTRRVLRMLVAVVVCFFLCWAPFHAQRLIAIYAPARGAKLRDQHE 322
                        |..|..|   |:|.:||.|:|:.|.:||||||..|::..|.....|:  :.|.
Zfish   275 ------------VNQRARH---RQVTKMLCALVIVFGICWAPFHIDRVMWSYIDDWTAE--NHHI 322

  Fly   323 FVYTVMTYVSGVLYYLSTCINPLLYNIMSHKFREAFKAVLFGKKVSKGSLNSRNNIESRRLRRAL 387
            |.|..:  :|||.:|||:.:||:|||:||.:|||.|:.|:..|...:.|:   :.:..|.:..|.
Zfish   323 FEYVHL--LSGVFFYLSSVVNPILYNLMSSRFREMFREVVCQKDHRQLSM---SRVTLRSVVSAS 382

  Fly   388 TNSSQTQRFSIESAEQPKPSIMQNPTNKP 416
            .::|.|..||::.          ||...|
Zfish   383 FSASNTVSFSVKF----------NPRELP 401

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PK1-R	NP_001014620.1	7tmA_capaR	21..358	CDD:320262	130/348 (37%)
		TM helix 1	21..48	CDD:320262	17/26 (65%)
		TM helix 2	55..81	CDD:320262	18/25 (72%)
		TM helix 3	94..124	CDD:320262	13/29 (45%)
		TM helix 4	136..158	CDD:320262	6/21 (29%)
		TM helix 5	178..207	CDD:320262	12/28 (43%)
		TM helix 6	277..307	CDD:320262	14/29 (48%)
		TM helix 7	326..351	CDD:320262	11/24 (46%)
nmur1b	XP_698473.4	7tm_GPCRs	60..356	CDD:475119	130/348 (37%)
		TM helix 1	62..86	CDD:410628	16/23 (70%)
		TM helix 2	95..117	CDD:410628	16/21 (76%)
		TM helix 3	134..156	CDD:410628	8/21 (38%)
		TM helix 4	179..195	CDD:410628	4/15 (27%)
		TM helix 5	228..251	CDD:410628	8/22 (36%)
		TM helix 6	285..307	CDD:410628	11/21 (52%)
		TM helix 7	324..349	CDD:410628	12/26 (46%)