DRSC/TRiP Functional Genomics Resources

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Protein Alignment PK1-R and ntsr1

DIOPT Version :9

Sequence 1:NP_001014620.1 Gene:PK1-R / 41713 FlyBaseID:FBgn0038201 Length:430 Species:Drosophila melanogaster
Sequence 2:XP_021329279.1 Gene:ntsr1 / 569344 ZFINID:ZDB-GENE-090313-372 Length:400 Species:Danio rerio


Alignment Length:381 Identity:112/381 - (29%)
Similarity:184/381 - (48%) Gaps:51/381 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly    23 VTVVYSLIFITGVVGN---ISTCIVIKKNRSMHTATNYYLFSLAISDFLLLLSGVPQEV-SYIWS 83
            |||:|.::|:.|.:||   :.|.:..|..:::.:..:|:|.||||||.|:|:..:|.|: ::||.
Zfish    56 VTVIYVVLFLIGCLGNSITLYTLLTKKSLQNLQSTVHYHLASLAISDLLILVLCMPIELYNFIWV 120

  Fly    84 KYPYVFGEYICIGRGLLAETSANATVLTITAFTVERYIAICHPFLGQAMSKLSRAIRIIVLVWIM 148
            .:|:.|||.:|.|...|.:..:.||...|.:.:|||::||||||..:::...||..::|..:||.
Zfish   121 HHPWAFGEAVCKGYYFLRDGCSYATAFNIASLSVERFMAICHPFKAKSIMSRSRTKKLISAMWIA 185

  Fly   149 AIVTAIPQAAQFGIEHYSGVEQCGIV--RVIVKHSFQLSTFIFFLAPMSIILVLYLLIGVHLYRS 211
            :...|.|.....|.:..:....|..:  .:..|...||:.|:.|:.||::|..|..:|...|.| 
Zfish   186 SFFLATPMLFTMGQQLMNDEYICTTIVSSITAKTVLQLNAFLSFVVPMALISALNGVIASQLLR- 249

  Fly   212 TLVEGPASVARRQQLKSVPSDTILYRYGGSGTAMSFNGGGSGAGTAGLMGGSGAQLSSVRGRLNH 276
                         ..:....|..:...||:.|.:|                  ..:...|.:...
Zfish   250 -------------MFRESAQDNRVCIIGGNATMLS------------------VAVEPNRAQSMR 283

  Fly   277 YGTRRVLRMLVAVVVCFFLCWAPFHAQRLIAIYAPARGAKLRDQHEFVYTVMTYVSGVLYYLSTC 341
            :|. .|||   |||:.|.:||.|:||:||:..|.......|.|.:.:.|    .|:.||:|:|:.
Zfish   284 HGV-MVLR---AVVIAFVVCWLPYHARRLMYCYVTEWTTALYDFYHYFY----MVTNVLFYVSSA 340

  Fly   342 INPLLYNIMSHKFREAFKAVLFGKKVSKGSLNSRNNIESRRLRRALTNSSQTQRFS 397
            |||:|||::|..:|:.|.:.|     ....|..|:..:.|.|.|...:....|.||
Zfish   341 INPILYNLVSANYRQIFFSTL-----RYLILPCRHKKQKRVLTRHSISICSNQTFS 391

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PK1-RNP_001014620.1 7tmA_capaR 21..358 CDD:320262 102/340 (30%)
TM helix 1 21..48 CDD:320262 10/27 (37%)
TM helix 2 55..81 CDD:320262 12/26 (46%)
TM helix 3 94..124 CDD:320262 10/29 (34%)
TM helix 4 136..158 CDD:320262 7/21 (33%)
TM helix 5 178..207 CDD:320262 10/28 (36%)
TM helix 6 277..307 CDD:320262 15/29 (52%)
TM helix 7 326..351 CDD:320262 11/24 (46%)
ntsr1XP_021329279.1 7tmA_NTSR1 54..357 CDD:320477 102/340 (30%)
TM helix 1 54..81 CDD:320477 9/24 (38%)
TM helix 2 91..117 CDD:320477 12/25 (48%)
TM helix 3 131..161 CDD:320477 10/29 (34%)
TM helix 4 173..195 CDD:320477 7/21 (33%)
TM helix 5 217..246 CDD:320477 10/28 (36%)
TM helix 6 280..310 CDD:320477 15/33 (45%)
TM helix 7 325..350 CDD:320477 12/28 (43%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D380940at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24243
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
33.020

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