DRSC/TRiP Functional Genomics Resources

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Protein Alignment PK1-R and NMUR2

DIOPT Version :9

Sequence 1:NP_001014620.1 Gene:PK1-R / 41713 FlyBaseID:FBgn0038201 Length:430 Species:Drosophila melanogaster
Sequence 2:NP_064552.3 Gene:NMUR2 / 56923 HGNCID:16454 Length:415 Species:Homo sapiens


Alignment Length:365 Identity:121/365 - (33%)
Similarity:194/365 - (53%) Gaps:73/365 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly    11 GPPRDPLAIVIPVTVVYSLIFITGVVGNISTCIVIKKNRSMHTATNYYLFSLAISDFLLLLSGVP 75
            ||.|.  ...:||:|||..||:.||:||:..|:||.::::|.|.|||||||||:||.|:||.|:|
Human    38 GPRRS--HFFLPVSVVYVPIFVVGVIGNVLVCLVILQHQAMKTPTNYYLFSLAVSDLLVLLLGMP 100

  Fly    76 QEVSYIWSKYPYVFGEYICIGRGLLAETSANATVLTITAFTVERYIAICHPFLGQAMSKLSRAIR 140
            .||..:|..||::||...|..:..|.||...|::|:||..:||||:||.|||..:..|...||:|
Human   101 LEVYEMWRNYPFLFGPVGCYFKTALFETVCFASILSITTVSVERYVAILHPFRAKLQSTRRRALR 165

  Fly   141 IIVLVWIMAIVTAIPQAAQFGIE-HY-------SGVEQCGIVRVIVKHSF--QLSTFIFFLAPMS 195
            |:.:||..:::.::|..:..||: ||       .|...|.:::.:..::|  |:::|:|:|.||:
Human   166 ILGIVWGFSVLFSLPNTSIHGIKFHYFPNGSLVPGSATCTVIKPMWIYNFIIQVTSFLFYLLPMT 230

  Fly   196 IILVLYLLIGVHLYRSTLV---EGPASVARRQQLKSVPSDTILYRYGGSGTAMSFNGGGSGAGTA 257
            :|.|||.|:.:.|.:...:   ||.|::.|..:                                
Human   231 VISVLYYLMALRLKKDKSLEADEGNANIQRPCR-------------------------------- 263

  Fly   258 GLMGGSGAQLSSVRGRLNHYGTRRVLRMLVAVVVCFFLCWAPFHAQRLIAIYAPARGAKLRDQHE 322
                                  :.|.:||..:|:.|.:||||||..||...:.......|    .
Human   264 ----------------------KSVNKMLFVLVLVFAICWAPFHIDRLFFSFVEEWSESL----A 302

  Fly   323 FVYTVMTYVSGVLYYLSTCINPLLYNIMSHKFREAFKAVL 362
            .|:.::..||||.:|||:.:||::||::|.:|:.||:.|:
Human   303 AVFNLVHVVSGVFFYLSSAVNPIIYNLLSRRFQAAFQNVI 342

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PK1-RNP_001014620.1 7tmA_capaR 21..358 CDD:320262 115/349 (33%)
TM helix 1 21..48 CDD:320262 14/26 (54%)
TM helix 2 55..81 CDD:320262 18/25 (72%)
TM helix 3 94..124 CDD:320262 13/29 (45%)
TM helix 4 136..158 CDD:320262 7/21 (33%)
TM helix 5 178..207 CDD:320262 12/30 (40%)
TM helix 6 277..307 CDD:320262 13/29 (45%)
TM helix 7 326..351 CDD:320262 11/24 (46%)
NMUR2NP_064552.3 7tm_1 62..327 CDD:278431 102/322 (32%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165145175
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E33208_3BGH7
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D380940at33208
OrthoFinder 1 1.000 - - FOG0001494
OrthoInspector 1 1.000 - - mtm8501
orthoMCL 1 0.900 - - OOG6_105236
Panther 1 1.100 - - O PTHR24243
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R5416
SonicParanoid 1 1.000 - - X673
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
User_Submission 00.000 Not matched by this tool.
1211.740

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