Protein Alignment PK1-R and PK2-R2

DIOPT Version :10

• Sequence 1: NP_001014620.1
• Gene: PK1-R / 41713
• FlyBaseID: FBgn0038201
• Length: 430
• Species: Drosophila melanogaster
• Sequence 2: NP_731788.1
• Gene: PK2-R2 / 41638
• FlyBaseID: FBgn0038139
• Length: 599
• Species: Drosophila melanogaster
• Alignment Length: 468
• Identity: 192/468 - (41%)
• Similarity: 255/468 - (54%)
• Gaps: 105/468 - (22%)

  Fly     1 MSAGNMS--------HDLGP---PRDPLAIVIPVTVVYSLIFITGVVGNISTCIVIKKNRSMHTA 54
            :||.|::        .:|.|   |..||:::..::|.|:||||.||:||:.|||||.:|..||||
  Fly    36 ISADNLTSLLQGLEPEELLPTVTPMTPLSLLATLSVGYALIFIAGVLGNLITCIVISRNNFMHTA 100

  Fly    55 TNYYLFSLAISDFLLLLSGVPQEVSYIWSKYPYVFGEYICIGRGLLAETSANATVLTITAFTVER 119
            ||:|||:|||||.:||.||:||::..:|....|.|.:.|||...:|:||:|||||||||||||||
  Fly   101 TNFYLFNLAISDMILLCSGMPQDLYNLWHPDNYPFSDSICILESVLSETAANATVLTITAFTVER 165

  Fly   120 YIAICHPFLGQAMSKLSRAIRIIVLVWIMAIVTAIPQAAQFGIEHYSGVEQCGIVRVIVKHSFQL 184
            ||||||||....|||||||::.|..:||.|::.|:|||.||.:........|.:......|.|.:
  Fly   166 YIAICHPFRQHTMSKLSRAVKFIFAIWIAALLLALPQAIQFSVVMQGMGTSCTMKNDFFAHVFAV 230

  Fly   185 STFIFFLAPMSIILVLYLLIGVHLYRSTLVEGPASVARRQQLKSVPSDTILYRYGGSGTAMSFNG 249
            |.|:||..||:.|.|||:||||.|.||.|::   ::.||                    ....|.
  Fly   231 SGFLFFGGPMTAICVLYVLIGVKLKRSRLLQ---ALPRR--------------------CYDVNR 272

  Fly   250 GGSGAGTAGLMGGSGAQLSSVRGRLNHYGTRRVLRMLVAVVVCFFLCWAPFHAQRLIAIYAPARG 314
            |.|            ||             .||:||||||.|.||:||||||||||:|:|....|
  Fly   273 GIS------------AQ-------------TRVIRMLVAVAVAFFICWAPFHAQRLMAVYGSTSG 312

  Fly   315 AKLRDQHEFVYTVMTYVSGVLYYLSTCINPLLYNIMSHKFREAFKAVLF------GKKVSKG--- 370
            .:.:..:: |::::.|.|||||:||||||||||||||||||||||..|.      ||...:|
  Fly   313 IESQWFND-VFSILDYTSGVLYFLSTCINPLLYNIMSHKFREAFKVTLARHFGLGGKNQGRGLPH 376

  Fly   371 --SLNSRNNIESRRL------RRALTNSSQT-----------------------QRFSIESAE-- 402
              |...||...|.||      |..:|:.:.|                       .|.|::|.:
  Fly   377 TYSALRRNQTGSLRLHTTDSVRTTMTSMATTTTGLNGSANGSGNGTTTGQSVRLNRVSLDSVQMQ 441

  Fly   403 ---QPKPSIMQNP 412
               :.:..:..||
  Fly   442 GQNRSRQDLFDNP 454

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PK1-R	NP_001014620.1	7tmA_capaR	21..358	CDD:320262	163/336 (49%)
		TM helix 1	21..48	CDD:320262	15/26 (58%)
		TM helix 2	55..81	CDD:320262	16/25 (64%)
		TM helix 3	94..124	CDD:320262	23/29 (79%)
		TM helix 4	136..158	CDD:320262	10/21 (48%)
		TM helix 5	178..207	CDD:320262	15/28 (54%)
		TM helix 6	277..307	CDD:320262	21/29 (72%)
		TM helix 7	326..351	CDD:320262	18/24 (75%)
PK2-R2	NP_731788.1	7tmA_capaR	69..355	CDD:320262	163/334 (49%)
		TM helix 1	69..94	CDD:320262	15/24 (63%)
		TM helix 2	101..127	CDD:320262	16/25 (64%)
		TM helix 3	140..170	CDD:320262	23/29 (79%)
		TM helix 4	182..204	CDD:320262	10/21 (48%)
		TM helix 5	225..253	CDD:320262	15/27 (56%)
		TM helix 6	275..305	CDD:320262	24/54 (44%)
		TM helix 7	323..348	CDD:320262	18/24 (75%)