Protein Alignment PK1-R and Gpr39

DIOPT Version :9

• Sequence 1: NP_001014620.1
• Gene: PK1-R / 41713
• FlyBaseID: FBgn0038201
• Length: 430
• Species: Drosophila melanogaster
• Sequence 2: NP_001107864.1
• Gene: Gpr39 / 288995
• RGDID: 1306745
• Length: 456
• Species: Rattus norvegicus
• Alignment Length: 477
• Identity: 119/477 - (24%)
• Similarity: 186/477 - (38%)
• Gaps: 135/477 - (28%)

  Fly    19 IVIPVTVVYSLIFITGVVGN---ISTCIVIKKNRSMHTATNYYLFSLAISDFLLLLSGVPQE-VS 79
            |.|.:|:||.::|:.|::||   |....|::|...:......::.|||.||.|:.|.|:|.| .|
  Rat    29 IKITLTLVYLIVFVVGILGNSVTIRVTQVLQKKGYLQKEVTDHMISLACSDILVFLIGMPMEFYS 93

  Fly    80 YIWSKYPYVFGEYI--CIGRGLLAETSANATVLTITAFTVERYIAICHPFLGQAMSKLSRAIRII 142
            .||:  |.....|.  |.....|.||.:.||:|.:...:.||||||||||..:.:|...:...:|
  Rat    94 IIWN--PLTTPSYALSCKLHTFLFETCSYATLLHVLTLSFERYIAICHPFRYKDVSGPCQVKLLI 156

  Fly   143 VLVWIMAIVTAIPQAAQFGIEH-------YSGVEQCGIVRVIVKHS------------------- 181
            ..||:.:.:.|:|.....|||:       :.|: .|.:.|  .:|.
  Rat   157 GFVWVTSALVALPLLFAMGIEYPLANVPTHKGL-NCNLSR--TRHHDHPGDSNMSICTNLSSRWE 218

  Fly   182 -FQLSTFIFFLAPMSIILVLYLLIGVHLYRSTLVEGPASVA------RRQQLKSVPSDTILYRYG 239
             ||.|.|..|        .:||::.|            |||      .:..:||
  Rat   219 VFQSSIFGAF--------AVYLVVLV------------SVAFMCWNMMKVLMKS----------- 252

  Fly   240 GSGTAMSFNGGGSGAGTAGLMGGSGAQLSSVRGRLNHYGT--RRVLRMLVAVVVCFFLCWAPFHA 302
                            ..|.:.|:|.||...:.......|  |:.:..|..:||...:||.|...
  Rat   253 ----------------KRGTLAGTGPQLQLRKSESEESRTARRQTIIFLRLIVVTLAVCWMPNQI 301

  Fly   303 QRLIAIYAPARGAKLRDQHEF------VYTVMTYVSGVLYYLSTCINPLLYNIMSHKFREAF--- 358
            :|::|...|        :|::      .|.::...|...:|||:.:||||||:.|.:||:.|
  Rat   302 RRIMAAAKP--------KHDWTKSYFKAYMILLPFSDTFFYLSSVVNPLLYNVSSQQFRKVFWQV 358

  Fly   359 ----------------KAVLFGKKVSKGSLNS--------RNNIESRRLRRALTNSSQTQRFSIE 399
                            :|.....|.|..|..|        |:|..|||..:...::.|.:...:|
  Rat   359 LCCRLTLQHANQEKQQRAYFSSTKNSSRSARSPLIFLASRRSNSSSRRTNKVFLSTFQAEAKPLE 423

  Fly   400 SAEQP-KPSIMQNPTNKPPVAA 420
            ...|| .|...|..:...|..:
  Rat   424 GEHQPLSPESPQTGSETKPAGS 445

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PK1-R	NP_001014620.1	7tmA_capaR	21..358	CDD:320262	100/383 (26%)
		TM helix 1	21..48	CDD:320262	10/29 (34%)
		TM helix 2	55..81	CDD:320262	11/26 (42%)
		TM helix 3	94..124	CDD:320262	12/29 (41%)
		TM helix 4	136..158	CDD:320262	5/21 (24%)
		TM helix 5	178..207	CDD:320262	8/48 (17%)
		TM helix 6	277..307	CDD:320262	9/31 (29%)
		TM helix 7	326..351	CDD:320262	10/24 (42%)
Gpr39	NP_001107864.1	7tm_1	47..344	CDD:278431	88/356 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D380940at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920