Protein Alignment PK1-R and MLNR

DIOPT Version :9

• Sequence 1: NP_001014620.1
• Gene: PK1-R / 41713
• FlyBaseID: FBgn0038201
• Length: 430
• Species: Drosophila melanogaster
• Sequence 2: NP_001498.1
• Gene: MLNR / 2862
• HGNCID: 4495
• Length: 412
• Species: Homo sapiens
• Alignment Length: 429
• Identity: 119/429 - (27%)
• Similarity: 181/429 - (42%)
• Gaps: 130/429 - (30%)

  Fly    12 PPRD-------PLAIVIPVTVVYSLIFITGVVGNISTCIVIKKNRSMHTATNYYLFSLAISDFLL 69
            ||.|       ||..::|||.|...:|:.||.||:.|.::|.:.|.|.|.||.||.|:|:||.|:
Human    23 PPCDERRCSPFPLGALVPVTAVCLCLFVVGVSGNVVTVMLIGRYRDMRTTTNLYLGSMAVSDLLI 87

  Fly    70 LLSGVPQEVSYIWSKYPYVFGEYICIGRGLLAETSANATVLTITAFTVERYIAICHPFLGQAMSK 134
            || |:|.::..:|...|:|||..:|.....:.|....||:|.:||.:||||:|||.|...:.:..
Human    88 LL-GLPFDLYRLWRSRPWVFGPLLCRLSLYVGEGCTYATLLHMTALSVERYLAICRPLRARVLVT 151

  Fly   135 LSRAIRIIVLVWIMAIVTAIPQAAQFGIEHYSGVE------------------------------ 169
            ..|...:|.::|.:|:::|.|.....|:|...|:.
Human   152 RRRVRALIAVLWAVALLSAGPFLFLVGVEQDPGISVVPGLNGTARIASSPLASSPPLWLSRAPPP 216

  Fly   170 ------------------------QCGIVRVIVKHSFQLSTFIFFLAPMSIILVLYLLIGVHLYR 210
                                    |.|.:||::    .::|..||| |...:.:||.|||..|:.
Human   217 SPPSGPETAEAAALFSRECRPSPAQLGALRVML----WVTTAYFFL-PFLCLSILYGLIGRELWS 276

  Fly   211 STL-VEGPASVARRQQLKSVPSDTILYRYGGSGTAMSFNGGGSGAGTAGLMGGSGAQLSSVRGRL 274
            |.. :.|||:..|.:
Human   277 SRRPLRGPAASGRER-------------------------------------------------- 291

  Fly   275 NHYGTRRVLRMLVAVVVCFFLCWAPFHAQRLIAIYAPARGAKLRDQHEFVYT-VMTYVSGVLYYL 338
               |.|:.:|:|:.||:.|.:||.|||..|:|.|       ...|.....:: ....|:..|:||
Human   292 ---GHRQTVRVLLVVVLAFIICWLPFHVGRIIYI-------NTEDSRMMYFSQYFNIVALQLFYL 346

  Fly   339 STCINPLLYNIMSHKFR-EAFKAVLFGKKVSKGSLNSRN 376
            |..|||:|||::|.|:| .|||.:|..|...:|...||:
Human   347 SASINPILYNLISKKYRAAAFKLLLARKSRPRGFHRSRD 385

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PK1-R	NP_001014620.1	7tmA_capaR	21..358	CDD:320262	106/393 (27%)
		TM helix 1	21..48	CDD:320262	11/26 (42%)
		TM helix 2	55..81	CDD:320262	13/25 (52%)
		TM helix 3	94..124	CDD:320262	12/29 (41%)
		TM helix 4	136..158	CDD:320262	6/21 (29%)
		TM helix 5	178..207	CDD:320262	10/28 (36%)
		TM helix 6	277..307	CDD:320262	13/29 (45%)
		TM helix 7	326..351	CDD:320262	11/25 (44%)
MLNR	NP_001498.1	7tm_1	55..355	CDD:278431	93/365 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D380940at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24243
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.020