DRSC/TRiP Functional Genomics Resources

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Protein Alignment PK1-R and Cckbr

DIOPT Version :9

Sequence 1:NP_001014620.1 Gene:PK1-R / 41713 FlyBaseID:FBgn0038201 Length:430 Species:Drosophila melanogaster
Sequence 2:NP_037297.2 Gene:Cckbr / 25706 RGDID:2290 Length:452 Species:Rattus norvegicus


Alignment Length:421 Identity:117/421 - (27%)
Similarity:177/421 - (42%) Gaps:113/421 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly     2 SAGNMSHDLGPPR------DPLAIVIPVTVVYSLIFITGVVGNISTCIVIKKNRSMHTATNYYLF 60
            ||||:|.:  |||      ..|.:.|.:| :|::||:..|.||:...:|:..:|.:.|.||.:|.
  Rat    33 SAGNLSCE--PPRIRGTGTRELEMAIRIT-LYAVIFLMSVGGNVLIIVVLGLSRRLRTVTNAFLL 94

  Fly    61 SLAISDFLLLLSGVPQEVSYIWSKYP-----YVFGEYICIGRGLLAETSANATVLTITAFTVERY 120
            |||:||.||.::.:|      ::..|     ::||..||.....|...|.:.:.|.:.|..:|||
  Rat    95 SLAVSDLLLAVACMP------FTLLPNLMGTFIFGTVICKAISYLMGVSVSVSTLNLVAIALERY 153

  Fly   121 IAICHPFLGQAMSKLSRAIRIIVLVWIMAIVTAIPQAAQFGIEHYSGVEQCG-----------IV 174
            .|||.|...:.....|.|.|:|:..|:::.:..:|...      |:.|:..|           ..
  Rat   154 SAICRPLQARVWQTRSHAARVILATWLLSGLLMVPYPV------YTMVQPVGPRVLQCMHRWPSA 212

  Fly   175 RVIVKHSFQLSTFIFFLAPMSIILVLYLLIGVHLYRSTLVEG-----PASVARRQQLKSVPSDTI 234
            ||....|..|...:||: |..:|.|.|.||...||.....:|     ..|.||.|  ..:|    
  Rat   213 RVQQTWSVLLLLLLFFI-PGVVIAVAYGLISRELYLGLHFDGENDSETQSRARNQ--GGLP---- 270

  Fly   235 LYRYGGSGTAMSFNGGG-----SGAGTAGLMGGSGAQLSSVRGRLNH------------------ 276
                ||:........||     |.||.    ...|..:...|.||..                  
  Rat   271 ----GGAAPGPVHQNGGCRPVTSVAGE----DSDGCCVQLPRSRLEMTTLTTPTPGPVPGPRPNQ 327

  Fly   277 ---YGTRRVLRMLVAVVVCFFLCWAPFH------------AQRLIAIYAPARGAKLRDQHEFVYT 326
               ...:||:|||:.:|:.|||||.|.:            |||.::      ||.:    .|:: 
  Rat   328 AKLLAKKRVVRMLLVIVLLFFLCWLPVYSVNTWRAFDGPGAQRALS------GAPI----SFIH- 381

  Fly   327 VMTYVSGVLYYLSTCINPLLYNIMSHKFREA 357
                   :|.|:|.|:|||:|..|..:||:|
  Rat   382 -------LLSYVSACVNPLVYCFMHRRFRQA 405

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PK1-RNP_001014620.1 7tmA_capaR 21..358 CDD:320262 108/396 (27%)
TM helix 1 21..48 CDD:320262 9/26 (35%)
TM helix 2 55..81 CDD:320262 11/25 (44%)
TM helix 3 94..124 CDD:320262 9/29 (31%)
TM helix 4 136..158 CDD:320262 6/21 (29%)
TM helix 5 178..207 CDD:320262 10/28 (36%)
TM helix 6 277..307 CDD:320262 15/41 (37%)
TM helix 7 326..351 CDD:320262 8/24 (33%)
CckbrNP_037297.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..21
7tm_GPCRs 55..406 CDD:421689 108/397 (27%)
TM helix 1 56..82 CDD:410628 9/26 (35%)
TM helix 2 89..115 CDD:410628 11/31 (35%)
TM helix 3 127..157 CDD:410628 9/29 (31%)
TM helix 4 170..191 CDD:410628 5/20 (25%)
TM helix 5 215..244 CDD:410628 10/29 (34%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 257..286 9/38 (24%)
TM helix 6 331..361 CDD:410628 12/29 (41%)
TM helix 7 374..399 CDD:410628 11/36 (31%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 421..452
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24243
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
22.010

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