DRSC/TRiP Functional Genomics Resources

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Protein Alignment PK1-R and Nmur2

DIOPT Version :9

Sequence 1:NP_001014620.1 Gene:PK1-R / 41713 FlyBaseID:FBgn0038201 Length:430 Species:Drosophila melanogaster
Sequence 2:NP_694719.2 Gene:Nmur2 / 216749 MGIID:2441765 Length:395 Species:Mus musculus


Alignment Length:363 Identity:122/363 - (33%)
Similarity:198/363 - (54%) Gaps:69/363 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly    11 GPPRDPLAIVIPVTVVYSLIFITGVVGNISTCIVIKKNRSMHTATNYYLFSLAISDFLLLLSGVP 75
            ||.|..|:  :||:|||:|||:.||:||:..|:||.:::::.|.|||||||||:||.|:||.|:|
Mouse    30 GPKRSDLS--LPVSVVYALIFVVGVIGNLLVCLVIARHQTLKTPTNYYLFSLAVSDLLVLLLGMP 92

  Fly    76 QEVSYIWSKYPYVFGEYICIGRGLLAETSANATVLTITAFTVERYIAICHPFLGQAMSKLSRAIR 140
            .||..:|..||::||...|..:..|.||...|::|::|..::|||:||.|||..:..|...||:|
Mouse    93 LEVYELWHNYPFLFGPVGCYFKTALFETVCFASILSVTTVSIERYVAIVHPFRAKLESTRRRALR 157

  Fly   141 IIVLVWIMAIVTAIPQAAQFGIEHYS--------GVEQCGIVRVIVKHSF--QLSTFIFFLAPMS 195
            |:.|||..::|.::|..:..||:...        |...|.:.:.|..::|  |.::|:|::.||:
Mouse   158 ILSLVWSFSVVFSLPNTSIHGIKFQQFPNGSSVPGSATCTVTKPIWVYNFIIQATSFLFYILPMT 222

  Fly   196 IILVLYLLIGVHLYRSTLVEGPASVARRQQLKSVPSDTILYRYGGSGTAMSFNGGGSGAGTAGLM 260
            :|.|||.|:|:.|.|.               :|:.:|.:                     |..: 
Mouse   223 LISVLYYLMGLRLKRD---------------ESLEADKV---------------------TVNI- 250

  Fly   261 GGSGAQLSSVRGRLNHYGTRR-VLRMLVAVVVCFFLCWAPFHAQRLIAIYAPARGAKLRDQHEFV 324
                           |..:|: |.:||..:|:.|.:||.|||..||...:..    :..:....|
Mouse   251 ---------------HRPSRKSVTKMLFVLVLVFAICWTPFHVDRLFFSFVD----EWTESLAAV 296

  Fly   325 YTVMTYVSGVLYYLSTCINPLLYNIMSHKFREAFKAVL 362
            :.::..||||.:|||:.:||::||::|.:||.||:.|:
Mouse   297 FNLIHVVSGVFFYLSSAVNPIIYNLLSRRFRAAFRNVV 334

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PK1-RNP_001014620.1 7tmA_capaR 21..358 CDD:320262 115/347 (33%)
TM helix 1 21..48 CDD:320262 15/26 (58%)
TM helix 2 55..81 CDD:320262 18/25 (72%)
TM helix 3 94..124 CDD:320262 11/29 (38%)
TM helix 4 136..158 CDD:320262 9/21 (43%)
TM helix 5 178..207 CDD:320262 12/30 (40%)
TM helix 6 277..307 CDD:320262 13/30 (43%)
TM helix 7 326..351 CDD:320262 11/24 (46%)
Nmur2NP_694719.2 7tm_4 48..333 CDD:304433 110/340 (32%)
7tm_1 54..319 CDD:278431 100/320 (31%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167835276
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E33208_3BGH7
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D380940at33208
OrthoFinder 1 1.000 - - FOG0001494
OrthoInspector 1 1.000 - - mtm8878
orthoMCL 1 0.900 - - OOG6_105236
Panther 1 1.100 - - O PTHR24243
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R5416
SonicParanoid 1 1.000 - - X673
SwiftOrtho 1 1.000 - -
TreeFam 1 0.960 - -
1312.740

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