DRSC/TRiP Functional Genomics Resources

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Protein Alignment PK1-R and npr-20

DIOPT Version :9

Sequence 1:NP_001014620.1 Gene:PK1-R / 41713 FlyBaseID:FBgn0038201 Length:430 Species:Drosophila melanogaster
Sequence 2:NP_495888.3 Gene:npr-20 / 188226 WormBaseID:WBGene00011578 Length:410 Species:Caenorhabditis elegans


Alignment Length:391 Identity:104/391 - (26%)
Similarity:173/391 - (44%) Gaps:68/391 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly    19 IVIPVTVVYSLIFITGVVGNISTCIVIKKNRSMHTATNYYLFSLAISDFLLLLSGVPQEVSYI-- 81
            :.|||.::|.|:|:..:.||..|.||:..:..|.|.||::|.:|||:|.|:.:..:.|.:.:|  
 Worm    29 VKIPVMIIYCLVFVVCLSGNFLTLIVMTSHPMMRTPTNFFLSNLAIADLLVAIFCILQNMIHIVG 93

  Fly    82 -----WSKYPYVFGEYICIGRGLLAETSANATVLTITAFTVERYIAICHPFLGQAMSKLSRAIRI 141
                 |...|.:...|:.: ..::..|||...||.    ::|:|||:.||..|..:.........
 Worm    94 FDHGNWPLGPVMCKLYLGL-TNIMPCTSAGILVLV----SLEKYIAVLHPLSGLKLLTPEHRWVA 153

  Fly   142 IVLVWIMAIVTAIPQAAQFGIEHYSGVEQCGIVRVIVKHSFQLSTFIFFLAPMSIILVLYLLIGV 206
            .::||:::|:...|.........|.||..|....:.:.:||  |..:::|.|::.::.:|..|..
 Worm   154 TMIVWVISILVNFPYFLYAQNYTYLGVSACFRGSMPIWNSF--SFIVWYLIPLTALVFIYSRISH 216

  Fly   207 HLYRSTLVEGPASVARRQQLKSVPSDTILYRYGGSGTAMSFNGGGSGAGTAGLMGGSGAQLSSVR 271
            .|:.|       ...|:...:|..|:..|.|            |...|.||  ..||..|:.:  
 Worm   217 LLWTS-------DSNRQSSRQSHESNGSLER------------GNGYANTA--QPGSSWQMKN-- 258

  Fly   272 GRLNHY-------------------------GTRRVLRMLVAVVVCFFLCWAPFHAQRLIAIYAP 311
            ||:..|                         |.|:|:|:||||||.|.|...|.||:.|...:  
 Worm   259 GRIVVYKQESLLNVPKREKKVKEPKRPKDTEGRRKVVRLLVAVVVSFALLTFPHHARLLYTSF-- 321

  Fly   312 ARGAKLRDQHEFVYTVMTYVSGVLYYLSTCINPLLYNIMSHKFREAFKAVLFGKK-VSKGSLNSR 375
            ..|.........::..::|   :..::|:.|||:||..:|.:||.|...|:..:| |......||
 Worm   322 QTGTICNSNWTMIFQPLSY---IFLFISSAINPILYACLSKRFRNALSDVIHCRKGVFSRISRSR 383

  Fly   376 N 376
            |
 Worm   384 N 384

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PK1-RNP_001014620.1 7tmA_capaR 21..358 CDD:320262 97/368 (26%)
TM helix 1 21..48 CDD:320262 11/26 (42%)
TM helix 2 55..81 CDD:320262 9/25 (36%)
TM helix 3 94..124 CDD:320262 9/29 (31%)
TM helix 4 136..158 CDD:320262 4/21 (19%)
TM helix 5 178..207 CDD:320262 7/28 (25%)
TM helix 6 277..307 CDD:320262 17/54 (31%)
TM helix 7 326..351 CDD:320262 7/24 (29%)
npr-20NP_495888.3 7tmA_Trissin_R 32..365 CDD:320140 96/367 (26%)
TM helix 1 33..57 CDD:320140 9/23 (39%)
TM helix 2 66..88 CDD:320140 8/21 (38%)
TM helix 3 107..129 CDD:320140 6/26 (23%)
TM helix 4 152..168 CDD:320140 3/15 (20%)
TM helix 5 189..212 CDD:320140 5/24 (21%)
TM helix 6 292..317 CDD:320140 14/24 (58%)
TM helix 7 333..358 CDD:320140 7/27 (26%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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