DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PK1-R and LOC108648264

DIOPT Version :9

Sequence 1:	NP_001014620.1	Gene:	PK1-R / 41713	FlyBaseID:	FBgn0038201	Length:	430	Species:	Drosophila melanogaster
Sequence 2:	XP_017951879.1	Gene:	LOC108648264 / 108648264	-ID:	-	Length:	351	Species:	Xenopus tropicalis

Alignment Length:	402	Identity:	128/402 - (31%)
Similarity:	191/402 - (47%)	Gaps:	102/402 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 IVIPVTVVYSLIFITGVVGNISTCIVIKKNRSMHTATNYYLFSLAISDFLLLLSGVPQEVSYIWS 83
            :::|||::...:|:.|:.||:.|.||.|:.|.|.:..|.||.|:|:||.|:.| |:|.::..||.
Frog    29 VLVPVTILCISLFLLGITGNLLTIIVFKRYRDMRSTVNMYLSSMAVSDILIFL-GLPSDLYRIWK 92

  Fly    84 KYPYVFGEYICIGRGLLAETSANATVLTITAFTVERYIAICHPFLGQAMSKLSRAIRIIVLVWIM 148
            ..||.||.::|.....|:|:....|:|.||..::|||||||.|...:.:....|...:|:|:||.
Frog    93 YKPYAFGNFVCKFLVYLSESCTYCTILHITMVSIERYIAICFPLKAKIIITKRRVKIVIILLWIF 157

  Fly   149 AIVTAIPQAAQFGIEHYSGVE--------------QCGIVRVIVKHSFQLSTFIFFLAPMSIILV 199
            |::||.|....||:||..|.:              |.|::.|:.    .:||..||| ||..:..
Frog   158 ALLTASPILFLFGVEHPPGFQPEETKECKYTEQSAQNGLLHVMT----WVSTIYFFL-PMFFLTF 217

  Fly   200 LYLLIGVHLYRSTLVEGPASVARRQQLKSVPSDTILYRYGGSGTAMSFNGGGSGAGTAGLMGGSG 264
            ||.||...|:::                         |:...|.|           ||.
Frog   218 LYGLICRKLWQT-------------------------RHWARGPA-----------TAN------ 240

  Fly   265 AQLSSVRGRLNHYGTRRVLRMLVAVVVCFFLCWAPFHAQRLIAIYAPARGAKLRDQHEFVYTVMT 329
                  ||:.|    :..::||..|||||.|||.|||..|::...|..        .|:|:..:|
Frog   241 ------RGKYN----KATVKMLAVVVVCFMLCWLPFHIGRILFALAGV--------GEYVFFEVT 287

  Fly   330 ----YVSGVLYYLSTCINPLLYNIMSHKFREAFKAVLFGKKVSKGSLNSRNNIESRRLRRALTNS 390
                .:|.||:|||..|||:||||||.|:|.|.:.:|:.|:          .::|.|.|
Frog   288 QYFNLLSMVLFYLSASINPMLYNIMSEKYRSAMRRMLYPKQ----------GLQSGRTR------ 336

  Fly   391 SQTQRFSIESAE 402
              :.|||:|..|
Frog   337 --SYRFSLEGTE 346

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PK1-R	NP_001014620.1	7tmA_capaR	21..358	CDD:320262	117/354 (33%)
		TM helix 1	21..48	CDD:320262	11/26 (42%)
		TM helix 2	55..81	CDD:320262	11/25 (44%)
		TM helix 3	94..124	CDD:320262	12/29 (41%)
		TM helix 4	136..158	CDD:320262	9/21 (43%)
		TM helix 5	178..207	CDD:320262	11/28 (39%)
		TM helix 6	277..307	CDD:320262	14/29 (48%)
		TM helix 7	326..351	CDD:320262	14/28 (50%)
LOC108648264	XP_017951879.1	7tm_GPCRs	31..319	CDD:391938	117/353 (33%)
		TM helix 1	33..57	CDD:341315	9/23 (39%)
		TM helix 2	66..87	CDD:341315	11/21 (52%)
		TM helix 3	104..126	CDD:341315	6/21 (29%)
		TM helix 4	149..165	CDD:341315	7/15 (47%)
		TM helix 5	197..220	CDD:341315	9/27 (33%)
		TM helix 6	246..271	CDD:341315	13/24 (54%)
		TM helix 7	288..313	CDD:341315	13/24 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D380940at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010