Protein Alignment PK1-R and LOC108648264

DIOPT Version :10

• Sequence 1: NP_001014620.1
• Gene: PK1-R / 41713
• FlyBaseID: FBgn0038201
• Length: 430
• Species: Drosophila melanogaster
• Sequence 2: XP_017951879.1
• Gene: LOC108648264 / 108648264
• XenbaseID: XB-GENE-29091083
• Length: 351
• Species: Xenopus tropicalis
• Alignment Length: 402
• Identity: 128/402 - (31%)
• Similarity: 191/402 - (47%)
• Gaps: 102/402 - (25%)

  Fly    19 IVIPVTVVYSLIFITGVVGNISTCIVIKKNRSMHTATNYYLFSLAISDFLLLLSGVPQEVSYIWS 83
            :::|||::...:|:.|:.||:.|.||.|:.|.|.:..|.||.|:|:||.|:.| |:|.::..||.
 Frog    29 VLVPVTILCISLFLLGITGNLLTIIVFKRYRDMRSTVNMYLSSMAVSDILIFL-GLPSDLYRIWK 92

  Fly    84 KYPYVFGEYICIGRGLLAETSANATVLTITAFTVERYIAICHPFLGQAMSKLSRAIRIIVLVWIM 148
            ..||.||.::|.....|:|:....|:|.||..::|||||||.|...:.:....|...:|:|:||.
 Frog    93 YKPYAFGNFVCKFLVYLSESCTYCTILHITMVSIERYIAICFPLKAKIIITKRRVKIVIILLWIF 157

  Fly   149 AIVTAIPQAAQFGIEHYSGVE--------------QCGIVRVIVKHSFQLSTFIFFLAPMSIILV 199
            |::||.|....||:||..|.:              |.|::.|:.    .:||..||| ||..:..
 Frog   158 ALLTASPILFLFGVEHPPGFQPEETKECKYTEQSAQNGLLHVMT----WVSTIYFFL-PMFFLTF 217

  Fly   200 LYLLIGVHLYRSTLVEGPASVARRQQLKSVPSDTILYRYGGSGTAMSFNGGGSGAGTAGLMGGSG 264
            ||.||...|:::                         |:...|.|           ||.
 Frog   218 LYGLICRKLWQT-------------------------RHWARGPA-----------TAN------ 240

  Fly   265 AQLSSVRGRLNHYGTRRVLRMLVAVVVCFFLCWAPFHAQRLIAIYAPARGAKLRDQHEFVYTVMT 329
                  ||:.|    :..::||..|||||.|||.|||..|::...|..        .|:|:..:|
 Frog   241 ------RGKYN----KATVKMLAVVVVCFMLCWLPFHIGRILFALAGV--------GEYVFFEVT 287

  Fly   330 ----YVSGVLYYLSTCINPLLYNIMSHKFREAFKAVLFGKKVSKGSLNSRNNIESRRLRRALTNS 390
                .:|.||:|||..|||:||||||.|:|.|.:.:|:.|:          .::|.|.|
 Frog   288 QYFNLLSMVLFYLSASINPMLYNIMSEKYRSAMRRMLYPKQ----------GLQSGRTR------ 336

  Fly   391 SQTQRFSIESAE 402
              :.|||:|..|
 Frog   337 --SYRFSLEGTE 346

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PK1-R	NP_001014620.1	7tmA_capaR	21..358	CDD:320262	117/354 (33%)
		TM helix 1	21..48	CDD:320262	11/26 (42%)
		TM helix 2	55..81	CDD:320262	11/25 (44%)
		TM helix 3	94..124	CDD:320262	12/29 (41%)
		TM helix 4	136..158	CDD:320262	9/21 (43%)
		TM helix 5	178..207	CDD:320262	11/28 (39%)
		TM helix 6	277..307	CDD:320262	14/29 (48%)
		TM helix 7	326..351	CDD:320262	14/28 (50%)
LOC108648264	XP_017951879.1	7tm_GPCRs	31..319	CDD:475119	117/353 (33%)
		TM helix 1	33..57	CDD:320260	9/23 (39%)
		TM helix 2	66..87	CDD:320260	11/21 (52%)
		TM helix 3	104..126	CDD:320260	6/21 (29%)
		TM helix 4	149..165	CDD:320260	7/15 (47%)
		TM helix 5	197..220	CDD:320260	9/27 (33%)
		TM helix 6	249..271	CDD:320260	13/21 (62%)
		TM helix 7	288..313	CDD:320260	13/24 (54%)