DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PK1-R and LOC101732366

DIOPT Version :9

Sequence 1:	NP_001014620.1	Gene:	PK1-R / 41713	FlyBaseID:	FBgn0038201	Length:	430	Species:	Drosophila melanogaster
Sequence 2:	XP_004918724.1	Gene:	LOC101732366 / 101732366	-ID:	-	Length:	373	Species:	Xenopus tropicalis

Alignment Length:	380	Identity:	88/380 - (23%)
Similarity:	164/380 - (43%)	Gaps:	91/380 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 PPRDPLAIVI----PVTVVYSLIFITGVVGNISTCIVIK-----KNRSMHTATNYYLFSLAISDF 67
            ||...:.:.|    .:::.|.|:...|::||   .:||:     :.|.:..:.::::.|||..|.
Frog    14 PPEAEVRLSIYAKSSISLTYMLLLFAGILGN---AMVIRVLWGLRRRRVQASLSHHMCSLASCDL 75

  Fly    68 LLLLSGVPQEV-SYIWSKYPYVFGEYICIGRGLLAETSANATVLTITAFTVERYIAICHPFLGQA 131
            |.|:.|:|.|: ..|||.:|:..|...|.|...|.|....|.:..:.:.:.||::|.|.|.   :
Frog    76 LQLVLGIPAELYGSIWSPFPWPLGNIGCCGFYYLWEVLCYAAIFNVLSLSCERHLATCRPL---S 137

  Fly   132 MSKLSRAIRI-IVLVWIMAIVTAIPQAAQFGIEHYSGVEQCGIVRVIVKHS-------------- 181
            :.....::|: :..:|:|:::..:|.....|:|.....:      |..:|:
Frog   138 LHLRQSSVRLRLCFIWLMSLLAGLPVLFTMGLEDVYAAD------VDDQHTELWVCTPLSSRKGL 196

  Fly   182 FQLSTFIFFLAPMSIILVLYLLIGVHLYRSTLVEGPASVARRQQLKSVPSDTILYRYGGSGTAMS 246
            |..:.:..||..:.::.|    :|:..:|           .|:.|:...|..:  ...|.|
Frog   197 FVATIWASFLTYLGVLSV----VGITCWR-----------MRRALQGSASQDV--EVAGPG---- 240

  Fly   247 FNGGGSGAGTAGLMGG--SGAQLSSVRGRLNHYGTRRVLRMLVAVVVCFFLCWAPFHAQRLIAIY 309
                    |:..|:|.  ||..:::         .::..|||..:|....:||.||.|:||:.:
Frog   241 --------GSVQLLGRFCSGQTVTA---------RKQNARMLGCIVGALAVCWLPFQARRLMTV- 287

  Fly   310 APARGAKLRDQHEFV------YTVMTYVSGVLYYLSTCINPLLYNIMSHKFREAF 358
                   ||.:.::.      |..:..::...||||:|:.|||||:.|..||.||
Frog   288 -------LRSKDQWTENYYRSYITLQPITNCFYYLSSCLTPLLYNLTSQSFRRAF 335

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PK1-R	NP_001014620.1	7tmA_capaR	21..358	CDD:320262	84/369 (23%)
		TM helix 1	21..48	CDD:320262	8/35 (23%)
		TM helix 2	55..81	CDD:320262	9/26 (35%)
		TM helix 3	94..124	CDD:320262	8/29 (28%)
		TM helix 4	136..158	CDD:320262	4/22 (18%)
		TM helix 5	178..207	CDD:320262	6/42 (14%)
		TM helix 6	277..307	CDD:320262	11/29 (38%)
		TM helix 7	326..351	CDD:320262	10/24 (42%)
LOC101732366	XP_004918724.1	7tm_GPCRs	27..335	CDD:391938	83/365 (23%)
		TM helix 1	29..53	CDD:341315	7/26 (27%)
		TM helix 2	64..86	CDD:341315	8/21 (38%)
		TM helix 3	104..126	CDD:341315	4/21 (19%)
		TM helix 4	147..163	CDD:341315	2/15 (13%)
		TM helix 5	194..217	CDD:341315	4/26 (15%)
		TM helix 6	259..284	CDD:341315	9/24 (38%)
		TM helix 7	303..328	CDD:341315	10/24 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D380940at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920