Protein Alignment PK1-R and trhr2

DIOPT Version :10

• Sequence 1: NP_001014620.1
• Gene: PK1-R / 41713
• FlyBaseID: FBgn0038201
• Length: 430
• Species: Drosophila melanogaster
• Sequence 2: XP_002936137.2
• Gene: trhr2 / 100498158
• XenbaseID: XB-GENE-1018399
• Length: 400
• Species: Xenopus tropicalis
• Alignment Length: 415
• Identity: 119/415 - (28%)
• Similarity: 189/415 - (45%)
• Gaps: 61/415 - (14%)

  Fly    26 VYSLIFI--TGVVGNISTCIVIKKNRSMHTATNYYLFSLAISDFLLLL-SGVP---QEVSYIWSK 84
            |:.::||  .|::|||...:|:...|.|.|.||.||.|||::|.::|: :|:|   ..::..|
 Frog    32 VFLVLFICGIGIIGNIMVVLVVFTTRDMRTPTNCYLVSLAVADLMVLVAAGLPNVSDSLAGTW-- 94

  Fly    85 YPYVFGEYICIGRGLLAETSANATVLTITAFTVERYIAICHPFLGQAMSKLSRAIRIIVLVWIMA 149
               |:|...|:|.........||:..:|||||||||||||||...|.:..:|||.|||.:|||.
 Frog    95 ---VYGHAGCLGITYFQYLGINASSCSITAFTVERYIAICHPMRAQTVCTVSRAKRIIAIVWIF- 155

  Fly   150 IVTAIPQAAQFGIE--HYSGVEQ--CG--IVRVIVKHSFQLSTFIFFLAPMSIILVLYLLIGVHL 208
              |:|.....|.:.  |.:..:|  ||  :.|.:....:.....||::.|:.:..:||.|||..|
 Frog   156 --TSIYCMFWFFLVDIHVNKSQQVECGYKVSRNLYLPIYLADFAIFYVTPLLVATILYGLIGRIL 218

  Fly   209 YRSTLVEGPASVARRQQLKSVPSDTILYRYGGSGTAMSFNGGGSGAGTAGLMGGSGAQLSSVRGR 273
            :.|.:.:.|.|...|.:.||....|                      .:...|...:.....:|.
 Frog   219 FLSPIPQHPESTTERWREKSSKEKT----------------------ESETEGNKPSNRLKTKGA 261

  Fly   274 LNHYGTRRVLRMLVAVVVCFFLCWAPFHAQRLIAIYAPARGAKLRDQHEFVYTVMTYVSGVLYYL 338
            |:  ..::|.:||..|||.|.|.|.|:....|:..:.         ...::.........:..|.
 Frog   262 LS--SRKQVTKMLAVVVVLFALLWMPYRTLVLVNSFM---------DKPYLDPWFLLFCRICVYA 315

  Fly   339 STCINPLLYNIMSHKFREAFKAVL-FGKKVSKGSLNSRNNIESRRLRRALTNSSQTQRFSIESAE 402
            ::.|||::||:||.|||.|||.:. .|.:..:.|:.......|.......|...:.::.|:|
 Frog   316 NSAINPVIYNLMSQKFRTAFKRLCKCGHEAQRRSIYMTTTSYSMVKDGVNTGGEKKEKQSLE--- 377

  Fly   403 QPKPSIMQNPTNK--PPVAAQYAMI 425
              |.:|:...|||  |.....|:::
 Frog   378 --KTNIIAKQTNKAGPEGDLYYSVV 400

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PK1-R	NP_001014620.1	7tmA_capaR	21..358	CDD:320262	103/343 (30%)
		TM helix 1	21..48	CDD:320262	8/23 (35%)
		TM helix 2	55..81	CDD:320262	11/29 (38%)
		TM helix 3	94..124	CDD:320262	15/29 (52%)
		TM helix 4	136..158	CDD:320262	11/21 (52%)
		TM helix 5	178..207	CDD:320262	8/28 (29%)
		TM helix 6	277..307	CDD:320262	11/29 (38%)
		TM helix 7	326..351	CDD:320262	6/24 (25%)
trhr2	XP_002936137.2	7tmA_TRH-R	30..335	CDD:320126	103/343 (30%)
		TM helix 1	30..56	CDD:320126	8/23 (35%)
		TM helix 2	63..88	CDD:320126	11/24 (46%)
		TM helix 3	101..131	CDD:320126	15/29 (52%)
		TM helix 4	144..165	CDD:320126	10/23 (43%)
		TM helix 5	188..217	CDD:320126	8/28 (29%)
		TM helix 6	263..293	CDD:320126	11/31 (35%)
		TM helix 7	303..328	CDD:320126	6/24 (25%)