DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Npc2b and heh-1

DIOPT Version :9

Sequence 1:	NP_650331.1	Gene:	Npc2b / 41710	FlyBaseID:	FBgn0038198	Length:	159	Species:	Drosophila melanogaster
Sequence 2:	NP_001379800.1	Gene:	heh-1 / 175426	WormBaseID:	WBGene00006452	Length:	154	Species:	Caenorhabditis elegans

Alignment Length:	161	Identity:	37/161 - (22%)
Similarity:	63/161 - (39%)	Gaps:	22/161 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 VIFAALIGFTSSTDVSQCPKSKSKALAAGDVSISNCP------KSKCILKRNTEASIQMKIRPER 67
            |||.||:|..::..:....|..........|....|.      |..|:.|:.:...||:..:|.:
Worm     4 VIFLALLGLAAAEFIEIGYKVCKSDGTVSQVKADGCELTVKDGKKVCLFKKGSRPIIQIAFKPSK 68

  Fly    68 DFQELTSDIQGIILDVPLPFPGYYGTSAC---PHIYDEAGEKKVGCPLKAGQVYTYKNSFKILPV 129
            |..:|.:.::..:           |.||.   |....:|....|.||:.||:...::.|..|...
Worm    69 DTDKLKTSVRAKV-----------GGSAMVDFPQTNSDACTYGVKCPVSAGENQIFEQSISITEN 122

  Fly   130 YPTVS-LEIHWGL-GDKHGDAACFQIPAKIK 158
            :|... ::::|.| ....|...|....|:||
Worm   123 HPAGEVIQVNWQLTRPDSGKEVCIIFLAEIK 153

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Npc2b	NP_650331.1	Npc2_like	23..155	CDD:238458	28/142 (20%)
heh-1	NP_001379800.1	Npc2_like	22..150	CDD:238458	28/138 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	56	1.000	Domainoid score	I7325
eggNOG	1	0.900	-	-		E1_KOG4063
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1612792at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11306
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.920