Protein Alignment foxo and HCM1

DIOPT Version :9

• Sequence 1: NP_001262557.1
• Gene: foxo / 41709
• FlyBaseID: FBgn0038197
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: NP_009991.2
• Gene: HCM1 / 850429
• SGDID: S000000661
• Length: 564
• Species: Saccharomyces cerevisiae
• Alignment Length: 488
• Identity: 109/488 - (22%)
• Similarity: 168/488 - (34%)
• Gaps: 160/488 - (32%)

  Fly    61 DSTKASNQQLAPGDSQQAIQ----NANAAKKNSSRRNAWGNLSYADLITHAIGSATDKRLTLSQI 121
            |:...||..|...:..|:::    |...|||..        .|||.||..||..:.:.:||||||
Yeast    79 DTCARSNGNLTLEEILQSLERRRINGELAKKPP--------YSYATLICLAILQSQEGKLTLSQI 135

  Fly   122 YEWMVQNVPYFKDKGDSNSSAGWKNSIRHNLSLHNRFMRVQNEGTGKSSWWMLNPEAKP------ 180
            |.|:..:.||:|.|     .|.|:|||||||||::.|::.:....||..:|.:.|.|:.
Yeast   136 YHWIHVHFPYYKQK-----DASWQNSIRHNLSLNDAFIKTEKSCDGKGHFWEVRPGAETKFFKGE 195

  Fly   181 --------------GKSVRRRAASMETSRYEKRRGR-----AKKRVEALRQAGV-VGLNDATPSP 225
                          ||.....:...|..:.|...|.     .::|.||.:...: :.||.   ||
Yeast   196 NRGYEFVKDSLQDIGKYFEIDSTLDELEQVESGEGNDDLPDEEEREEAGKFPSIEIQLNS---SP 257

  Fly   226 SSSVSEGLDHFPESPLHSGGGFQLSP-----DFRQRASSNASSCGRLSP---------------- 269
            ...||: |.|.|:....:.   .|:|     ..|....::.::...|.|
Yeast   258 ILRVSQ-LHHIPQLKTDNS---VLNPHENLESMRNMIENDVNNIDSLEPPYVMKKYHTSLGLPSL 318

  Fly   270 IRAQDLEPDWGFPVDYQNTTMTQAHAQALEELTGTMADE-----LTLCNQQQQGFS---AASGLP 326
            :.|:|     .|....:|..:|||:......:|...:.:     .|..|...:..|   :..|..
Yeast   319 VNAKD-----HFQAGVKNNNITQANRFNTLPITSAKSPQNFRKYFTSFNSNFEDLSPLRSNVGAG 378

  Fly   327 SQPPPPPYQP--------------PQHQQAQQQQQQQSPYALNG--------------------- 356
            |...|.||.|              ||.||:....|...|.:.:|
Yeast   379 SLLDPLPYSPLKLYDQKNLALMSKPQSQQSYSNSQLPPPPSSHGSDLLKTPKMRHSDGLEKTPSR 443

  Fly   357 ----PASGYNTLQP-QSQCLLHRSLNCSCMHNA---------------------RDGLSPNSVTT 395
                |..|.:.|:. |:...|...|.||.:..|                     |...:|:.:|:
Yeast   444 LISTPKDGNSILRKWQTPSHLFEDLYCSPLFRAIETPIRYITTPGGTLETQISPRKSSAPDVLTS 508

  Fly   396 TMSPAYPNS---------------EPSSDSLNT 413
            ..:..:.:|               |..||..||
Yeast   509 ATNSKFASSGLFGVDVYSVWKRATEKISDGNNT 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
foxo	NP_001262557.1	FH	95..175	CDD:238016	34/79 (43%)
HCM1	NP_009991.2	COG5025	20..564	CDD:227358	109/488 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810