Protein Alignment foxo and foxn3

DIOPT Version :10

• Sequence 1: NP_650330.3
• Gene: foxo / 41709
• FlyBaseID: FBgn0038197
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: NP_001038728.2
• Gene: foxn3 / 692291
• ZFINID: ZDB-GENE-060512-39
• Length: 441
• Species: Danio rerio
• Alignment Length: 500
• Identity: 110/500 - (22%)
• Similarity: 174/500 - (34%)
• Gaps: 183/500 - (36%)

  Fly    54 VEPTDELDSTKASNQQLAPGDSQ---QAIQNANAAKKNSSRRNAWGNLSYADLITHAIGSATDKR 115
            |.|..:||    .:...:|..|.   .|.||.|....          .|::.||..||..|..||
Zfish    84 VSPVQDLD----DDTPPSPAHSDLPYDAKQNPNCKPP----------YSFSCLIFMAIEDAPSKR 134

  Fly   116 LTLSQIYEWMVQNVPYFKDKGDSNSSAGWKNSIRHNLSLHNRFMRV---QNEGTGKSSWWMLNPE 177
            |.:..||.|::::.|||     :|:..|||||:||||||:..|.:|   :::..||.|.|.::||
Zfish   135 LPVKDIYNWILEHFPYF-----ANAPTGWKNSVRHNLSLNKCFKKVDKDRSQSIGKGSLWCIDPE 194

  Fly   178 AKPGKSVRRRAASMETSRYEKRRGRAKKRVEALRQAGVVGLNDATP-SPSSSVSEGLDHFPESPL 241
            .:                        :..::||::         || .|.|.|      |...|
Zfish   195 YR------------------------QNLIQALKK---------TPYHPYSQV------FTTPP- 219

  Fly   242 HSGGGFQLSPDFRQRASSNASSCGRLSPIRAQDLEPDW-GFPVDYQNTTMTQAHAQALEELTGTM 305
                   .||...|..||                .|.| |.|...:|..:      .|:...|.:
Zfish   220 -------TSPQAYQSMSS----------------PPIWPGSPFYRKNKGV------LLQVPQGVI 255

  Fly   306 ADELTLCNQQQQGFSAASGLPSQPPPPPYQPPQHQQA------------QQQQQQQSPYALNGP- 357
            .:...:.:|         ||.....|.|..|...:.|            ..:..|.||.|.:.|
Zfish   256 QNGARMMSQ---------GLFPGIRPLPINPIVSRTAAVRSVLGYRITSDTEPTQNSPLATSDPK 311

  Fly   358 ---------ASGYNTLQPQSQCLLHRSLNCSCMHNARDGLSPNSVTTTMSPAYPNSEPSSDSLNT 413
                     :|| :..:.::||               ||...|         :..:|..||:.:.
Zfish   312 EDHTYSFAKSSG-SDAEEEAQC---------------DGSELN---------FHTNETGSDAEDD 351

  Fly   414 YSNVVLDGP----ADTAALMVQQQQQQQQQQQLSASLEDNNCASTLIGQCLEVLNNEAQPIDEFN 474
            ..:.:...|    .|..||      .|.:::||...::....:.||             |:.:..
Zfish   352 DKSKIKKEPKEWSVDALAL------AQHKKRQLLTKVKQRVASDTL-------------PLKKRR 397

  Fly   475 LENFPVGNLECNVEELLQQEMSYGGLLDINIPLATVNTNLVNSSS 519
            .|..|    |.:.||:.:   :.|.||.:....|.:| |:.|.::
Zfish   398 TEKPP----ESDDEEMKE---AAGSLLHLAGVRACLN-NITNRTA 434

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
foxo	NP_650330.3	FH_FOXO	96..175	CDD:410806	33/81 (41%)
foxn3	NP_001038728.2	FH_FOXN3	114..203	CDD:410833	35/127 (28%)