Protein Alignment foxo and foxl2a

DIOPT Version :10

• Sequence 1: NP_650330.3
• Gene: foxo / 41709
• FlyBaseID: FBgn0038197
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: NP_001038717.1
• Gene: foxl2a / 692279
• ZFINID: ZDB-GENE-060512-241
• Length: 306
• Species: Danio rerio
• Alignment Length: 353
• Identity: 88/353 - (24%)
• Similarity: 132/353 - (37%)
• Gaps: 112/353 - (31%)

  Fly    60 LDSTKASNQQLAPGDSQQAIQNANAAKKNSSRRNAWGNLSYADLITHAIGSATDKRLTLSQIYEW 124
            :|:|.:|.::....|  :|.......|.:.:::..:   ||..||..||..:::||||||.||::
Zfish    16 MDTTSSSAEKDRTKD--EAPPEKGPDKSDPTQKPPY---SYVALIAMAIRESSEKRLTLSGIYQY 75

  Fly   125 MVQNVPYFKDKGDSNSSAGWKNSIRHNLSLHNRFMRVQNEGTG--KSSWWMLNPEAKPGKSVRRR 187
            ::...|:::     .:..||:|||||||||:..|::|..||.|  |.::|.|:|..:.
Zfish    76 IISKFPFYE-----KNKKGWQNSIRHNLSLNECFIKVPREGGGERKGNYWTLDPACED------- 128

  Fly   188 AASMETSRYEKRRGRAKKRVEALRQAGVVGLNDATPSPSSSVSEGLDHF-PESPLHSGGGF-QLS 250
              ..|...|.:|| |.|:...              |.|:        || |...|..|.|: .||
Zfish   129 --MFEKGNYRRRR-RMKRPFR--------------PPPT--------HFQPGKSLFGGEGYGYLS 168

  Fly   251 -PDFRQRASSNAS---------SC----GRLSPIRAQDLEPDWGFPVDYQNTTMTQAHAQALEEL 301
             |.:.|....|.|         ||    |.:||:..:.|..    |..|...:..|
Zfish   169 PPKYLQSGFINNSWSPAPMSYTSCQVSSGSVSPVNMKGLSA----PSSYNPYSRVQ--------- 220

  Fly   302 TGTMADELTLCNQQQQGFSAASGLPSQP------PPPPYQPPQHQQAQQQQQQQSPYALNGP--A 358
                                :.||||..      ....:....|..|....||.||.....|  .
Zfish   221 --------------------SIGLPSMVNSYNGISHHHHHHHTHPHALPHAQQLSPATAAAPPVT 265

  Fly   359 SGYNT-------LQPQSQCLLHRSLNCS 379
            :|..|       .||....::|    ||
Zfish   266 TGNGTGLQFACSRQPAELSMMH----CS 289

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
foxo	NP_650330.3	FH_FOXO	96..175	CDD:410806	33/80 (41%)
foxl2a	NP_001038717.1	FH_FOXL2	46..134	CDD:410802	36/104 (35%)