Protein Alignment foxo and foxj2

DIOPT Version :10

• Sequence 1: NP_650330.3
• Gene: foxo / 41709
• FlyBaseID: FBgn0038197
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: XP_686801.4
• Gene: foxj2 / 558490
• ZFINID: ZDB-GENE-100922-240
• Length: 516
• Species: Danio rerio
• Alignment Length: 627
• Identity: 131/627 - (20%)
• Similarity: 196/627 - (31%)
• Gaps: 198/627 - (31%)

  Fly    57 TDELDSTKASNQQLAPGDSQQAIQNANAAKKNSSRRNAWGN---------------------LSY 100
            |.||||:..|...|    .|..|....:.|:...|:...|.                     .||
Zfish     2 TSELDSSLTSIDWL----PQLGISTLRSGKERVERKKERGREKDIPLIPALSPGSNSKVKPPHSY 62

  Fly   101 ADLITHAIGSATDKRLTLSQIYEWMVQNVPYFKDKGDSNSSAGWKNSIRHNLSLHNRFMRV--QN 163
            |.||..||.||.:.:|:|:.||.|:....||:     ..:..||||||||||||:..|.:|  ..
Zfish    63 ATLIAMAISSAPEMKLSLNDIYTWISDTFPYY-----CRAGRGWKNSIRHNLSLNKCFRKVPRPQ 122

  Fly   164 EGTGKSSWWMLN--PEAKPGKSVRRRAASMETSRYEKRRGRAKKRVEALRQAGVVGLNDATPSPS 226
            ...||.|:|.::  ||:...:.|:|.....|                          :..||
Zfish   123 SDPGKGSYWTMDVPPESTQPRGVKRPYTDDE--------------------------HVVTP--- 158

  Fly   227 SSVSEGLDHFPESPLHSGGGFQLSPDFRQRASSNASSCGRLSPIRAQDLEP-------------- 277
                     |||:.|.:.....|.|....:::.....|.:...|......|
Zfish   159 ---------FPETQLPANQPEPLPPQPDTKSTFPPPPCKQRPAIPVPSSLPSNPHADPPLRFSFA 214

  Fly   278 DWGFPVDYQNTTMTQAHAQALEELTGTMADELTLCNQQQQGFSAASGLPSQPPPPPYQPPQHQQA 342
            |...| |..|:  .|:..:::.|...:.:|..||......  |.....|:.||..|...|...|.
Zfish   215 DLNLP-DLYNS--FQSLCRSMREKVTSQSDVSTLLGLTHD--STPLHTPTLPPLSPCPNPNINQF 274

  Fly   343 QQQQQQQSP-------YALNGPASGYNTLQPQSQCLLHRSLNCSCMHNARDGLSPNSVTTTMSPA 400
            ........|       :..|.|.|...||.|.....:|                ||| :|.....
Zfish   275 INPNSTHIPNLNTNGNFNPNAPHSFIPTLNPNQNSSIH----------------PNS-STEPDKV 322

  Fly   401 YPNSEPSS-----DSLN---------TYSNVVLDGPADTAALMVQQQQQQQQQQQLSASLEDNNC 451
            .||..|:.     |||.         .::|:.|....|   |:...:|.:.:...|..:|..:.|
Zfish   323 LPNVVPADWFSNPDSLRESFRIASSLDWANIDLSCHPD---LLESMRQAELRDWALDPALFTSLC 384

  Fly   452 ASTLIGQCLEVLNNEAQPIDEFNLENFPVGNLECNVEELLQQEMSYGGLLDINIPLATVNTNLVN 516
            .|                                     |.:..::.||:.             :
Zfish   385 DS-------------------------------------LNRFFTHKGLIG-------------S 399

  Fly   517 SSSGPLSI------------SNISNLSNISSNS----GSSLSLNQLQAQLQQQQQQQQAQQQQQA 565
            ||.||.|.            :|...||:::..|    .|.|.....:|.||..::......|.|.
Zfish   400 SSGGPSSFGHMAPPSVNMPPTNPPTLSSLTQPSPLIYPSQLPPGSGEAPLQGPRRNLTPLAQNQT 464

  Fly   566 QQQQQQHQQHQQQLLLNNNNNSSSSLELATQTATTNLNARVQ 607
            .|.....|....|.:..|..::......|.....|.::..:|
Zfish   465 TQTPGGLQPTTSQPMTPNALHTQPLTPSARPPLKTGISEEIQ 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
foxo	NP_650330.3	FH_FOXO	96..175	CDD:410806	35/101 (35%)
foxj2	XP_686801.4	COG5025	<21..>181	CDD:227358	50/202 (25%)
		Forkhead	57..134	CDD:459732	34/81 (42%)
		PHA03247	<116..499	CDD:223021	88/495 (18%)