Protein Alignment foxo and foxd4l1

DIOPT Version :10

• Sequence 1: NP_650330.3
• Gene: foxo / 41709
• FlyBaseID: FBgn0038197
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: NP_001016928.1
• Gene: foxd4l1 / 549682
• XenbaseID: XB-GENE-479247
• Length: 352
• Species: Xenopus tropicalis
• Alignment Length: 345
• Identity: 89/345 - (25%)
• Similarity: 139/345 - (40%)
• Gaps: 75/345 - (21%)

  Fly    53 FVEPT-DEL-DSTKASNQQLA--PGDSQQAIQNANAAKKNSSRRNAWGN---------LSYADLI 104
            :::|| .|: ||...|..:|:  ..:|..:.::.....|:|....:.|.         .||..||
 Frog    42 YLQPTHSEMGDSGILSPSKLSCTESESDSSGESEGGTSKDSPATPSGGKAKRALVKPPYSYIALI 106

  Fly   105 THAIGSATDKRLTLSQIYEWMVQNVPYFKDKGDSNSSAGWKNSIRHNLSLHNRFMRVQNE--GTG 167
            |.||..:..|:||||.|.:::....||:|||     ...|:|||||||||::.|:::..|  ..|
 Frog   107 TMAILQSPHKKLTLSGICDFISSKFPYYKDK-----FPAWQNSIRHNLSLNDCFIKIPREPGNPG 166

  Fly   168 KSSWWMLNPEAKPGKSVRRRAASMETSRYEKRRGRAKKRVEALRQAGVVGLNDATPSPSSSVSEG 232
            |.::|.|:|.::.         ..:...:.:||.|.|:..:...:.|:|..|   |.|.
 Frog   167 KGNYWTLDPASED---------MFDNGSFLRRRKRFKRHQQEFFKDGLVMYN---PLPY------ 213

  Fly   233 LDHFPESPLHSGGGFQLSPDFRQRASSNASSCGRLSPIRAQDLEPDWGFPVDYQNTTMTQAHAQA 297
              :.|.|.:......|.:|........|.:....|||.      ||....|.|.:    |...:.
 Frog   214 --YRPYSTIQPQQVLQQTPVACMAIPENLTMPTHLSPY------PDIKRKVPYPD----QGVHRG 266

  Fly   298 LEELTGTMADELTLCNQQQQGFSAASGL--PSQPPPPPYQPPQHQQAQQQQQQQSPYALNGPASG 360
            .|.|.   ||.....:|.:..||..:.:  |.:|.|                   .::...|...
 Frog   267 FEALD---ADNHPNKSQSKCSFSIENIMRKPKEPEP-------------------SFSTFNPHWN 309

  Fly   361 YN-TLQPQSQCLLHRSLNCS 379
            || .||..:.|||...||.|
 Frog   310 YNHLLQRPNSCLLPAVLNLS 329

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
foxo	NP_650330.3	FH_FOXO	96..175	CDD:410806	34/89 (38%)
foxd4l1	NP_001016928.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..32
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	47..92		9/44 (20%)
		FH_FOXD4-like	97..185	CDD:410822	35/101 (35%)