DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment foxo and FoxP

DIOPT Version :9

Sequence 1:	NP_001262557.1	Gene:	foxo / 41709	FlyBaseID:	FBgn0038197	Length:	622	Species:	Drosophila melanogaster
Sequence 2:	NP_001247011.1	Gene:	FoxP / 41182	FlyBaseID:	FBgn0262477	Length:	520	Species:	Drosophila melanogaster

Alignment Length:	196	Identity:	60/196 - (30%)
Similarity:	83/196 - (42%)	Gaps:	53/196 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    74 DSQQAIQNANAAKKNSSRRNAWGNLSYADLITHAIGSATDKRLTLSQIYEWMVQNVPYFKDKGDS 138
            |.||.|.......||:..|..:   :||.||..||..:.||:|||::||.|......||:
  Fly   310 DVQQEIHRNREFYKNADVRPPF---TYASLIRQAIIDSPDKQLTLNEIYNWFQNTFCYFR----- 366

  Fly   139 NSSAGWKNSIRHNLSLHNRFMRVQNEGTGKSSWWMLNPEAKPGKSVRRRAASMETSRYEKRRGRA 203
            .::|.|||:||.|||||..|:|.:::   ..|:||::    ..:.|:||..|         |||.
  Fly   367 RNAATWKNAIRTNLSLHKCFVRYEDD---FGSFWMVD----DNEFVKRRHLS---------RGRP 415

  Fly   204 KKRVEALRQAGVVGLNDATPSPSSSVSEGLDHFPESPLHSGGGFQLSPDFRQRASSNASSCGRLS 268
            :|.                 .||||        |.| ..||.|.   |..:....:....|..|.
  Fly   416 RKY-----------------EPSSS--------PNS-CQSGNGV---PTDKNPCDNCTQHCTSLP 451

  Fly   269 P 269
            |
  Fly   452 P 452

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
foxo	NP_001262557.1	FH	95..175	CDD:238016	32/79 (41%)
FoxP	NP_001247011.1	FOXP-CC	157..224	CDD:292777
FoxP	NP_001247011.1	FH	328..400	CDD:238016	33/82 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445499
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840