Protein Alignment foxo and foxi3a

DIOPT Version :10

• Sequence 1: NP_650330.3
• Gene: foxo / 41709
• FlyBaseID: FBgn0038197
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: NP_944599.2
• Gene: foxi3a / 387257
• ZFINID: ZDB-GENE-031126-3
• Length: 353
• Species: Danio rerio
• Alignment Length: 306
• Identity: 74/306 - (24%)
• Similarity: 114/306 - (37%)
• Gaps: 90/306 - (29%)

  Fly    99 SYADLITHAIGSATDKRLTLSQIYEWMVQNVPYFKDKGDSNSSAGWKNSIRHNLSLHNRFMRVQN 163
            ||:.||..||..|.::||||||||:::..|.|::     :.|.|.|:|||||||||::.||:|..
Zfish   120 SYSALIAMAIHGAPNRRLTLSQIYQYVADNFPFY-----NKSKASWQNSIRHNLSLNDCFMKVPR 179

  Fly   164 EGT--GKSSWWMLNPEAKPGKSVRRRAASMETSRYEKRRGRAKKRVEALRQAGVVGLNDATPSPS 226
            :.:  ||.::|.|:|..:         ...:...:.::|.|....:......|..|.:.|..||.
Zfish   180 DDSDPGKGNYWTLDPNCE---------KMFDNGNFRRKRKRKSDSLAEEEGKGYSGSDSALSSPK 235

  Fly   227 SSVSEGLDHFPESPLHSGGGFQLSPDFRQRASSNASSCGRLSPIRAQDLEPDWGFPVDYQNTTMT 291
            :                              .|::|..|                     |:.::
Zfish   236 N------------------------------PSDSSERG---------------------NSPIS 249

  Fly   292 QAHAQALEELTGTMADELTLCNQQQQGFSAASGLPSQPPPPPYQPPQHQQAQQQQQQQSPYALNG 356
            ...|..|......|.|             .|||......|.|...|       ..|:.||..:.|
Zfish   250 TDQAPCLNSFLNQMGD-------------VASGSREALLPSPLAVP-------LSQRSSPTGVYG 294

  Fly   357 PASGYNTLQPQSQCLLHRSLNCSCMHNARDGLSPNSVTTTMSPAYP 402
            ..|. |...||.:..:.:|...|..:  :||.|.:.:....|..||
Zfish   295 SYSP-NATMPQWETQIPQSSISSTPY--KDGYSDSMLNPYSSQLYP 337

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
foxo	NP_650330.3	FH_FOXO	96..175	CDD:410806	35/77 (45%)
foxi3a	NP_944599.2	FH_FOXI1	113..212	CDD:410827	38/105 (36%)
		COG5025	117..>323	CDD:227358	69/290 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	201..255		12/104 (12%)
		Nuclear localization signal. /evidence=ECO:0000250|UniProtKB:A8MTJ6	206..212		1/5 (20%)