Protein Alignment foxo and Foxb1

DIOPT Version :10

• Sequence 1: NP_650330.3
• Gene: foxo / 41709
• FlyBaseID: FBgn0038197
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: NP_001013266.2
• Gene: Foxb1 / 367106
• RGDID: 1305217
• Length: 325
• Species: Rattus norvegicus
• Alignment Length: 348
• Identity: 79/348 - (22%)
• Similarity: 130/348 - (37%)
• Gaps: 106/348 - (30%)

  Fly    92 RNAWGN----LSYADLITHAIGSATDKRLTLSQIYEWMVQNVPYFKDKGDSNSSAGWKNSIRHNL 152
            ||.:.:    .||..|...||.|:.:|.|.||:||::::...||:::     ::..|:||:||||
  Rat     6 RNTYSDQKPPYSYISLTAMAIQSSPEKMLPLSEIYKFIMDRFPYYRE-----NTQRWQNSLRHNL 65

  Fly   153 SLHNRFMRV--QNEGTGKSSWWMLNPEA----KPGKSVRRR-----------AASMETSRYEKRR 200
            |.::.|:::  :.:..||.|:|.|:|..    :.|..:|||           |.|......:..:
  Rat    66 SFNDCFIKIPRRPDQPGKGSFWALHPSCGDMFENGSFLRRRKRFKVLKSDHLAPSKPADAAQYLQ 130

  Fly   201 GRAKKRVEALRQAGVVGLNDATPSPSSSVSEGLDHFPESP--LHSGGGFQLSPDF---------- 253
            .:||.|:.||..:|.                   |.|:.|  .::.||......|
  Rat   131 QQAKLRLSALAASGT-------------------HLPQMPAAAYNLGGVAQPSGFKHPFAIENII 176

  Fly   254 -RQRASSNASSCGRLSPIRAQDLEPDWGFPVDYQNTTMTQAHAQALEELTGT--MADELT----- 310
             |:.......:...:.|:.|       .:|:..|.|||..:.......:.|:  |.|..|
  Rat   177 AREYKMPGGLAFSAMQPVPA-------AYPLPNQLTTMGSSLGTGWPHVYGSAGMIDSATPISMA 234

  Fly   311 -------------LCNQQQQGF-----------SAASGLPSQP---------PPPPYQPPQHQQA 342
                         ||:...|..           :|...||:.|         .||...|...|.|
  Rat   235 SGDYSAYGVPLKPLCHAAGQTLPAIPVPIKPTPAAVPALPALPAPIPTLLSNSPPSLSPTSSQTA 299

  Fly   343 QQQQQQQSP-YALNGPASGYNTL 364
            ..|....:| ..|..|||..:::
  Rat   300 TSQSSPATPSETLTSPASALHSV 322

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
foxo	NP_650330.3	FH_FOXO	96..175	CDD:410806	27/84 (32%)
Foxb1	NP_001013266.2	FH_FOXB2	1..110	CDD:410817	35/108 (32%)