Protein Alignment foxo and CHES-1-like

DIOPT Version :10

• Sequence 1: NP_650330.3
• Gene: foxo / 41709
• FlyBaseID: FBgn0038197
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: NP_511071.3
• Gene: CHES-1-like / 31678
• FlyBaseID: FBgn0029504
• Length: 1268
• Species: Drosophila melanogaster
• Alignment Length: 609
• Identity: 147/609 - (24%)
• Similarity: 226/609 - (37%)
• Gaps: 163/609 - (26%)

  Fly    81 NANAAKKNSSRRNAWGN---------------LSYADLITHAIGSATDKRLTLSQIYEWMVQNVP 130
            |.:.|..|:.::....|               .|::.||..||..:.:|.|.:.:||.|:||:.|
  Fly   671 NGSGAGSNTPQKQKHPNNVPYDPLVHTNNKPPYSFSSLIFMAIEGSNEKALPVKEIYAWIVQHFP 735

  Fly   131 YFKDKGDSNSSAGWKNSIRHNLSLHNRFMRVQN-EGTGKSSWWMLNPEAK-------------PG 181
            |||     .:..|||||:||||||:..|::|:. ...||.|.|.:.|:.:             |.
  Fly   736 YFK-----TAPNGWKNSVRHNLSLNKSFVKVEKAPNMGKGSLWRVEPQQRQNLIQALNRSPFFPN 795

  Fly   182 KSVRRRAASMET----SRYEKRRGRAKKRVEALRQ----AGV-----VGLNDATPSPSSSVSEGL 233
            .:|.:.:.|:::    |.|:...|.....|.:.:.    |||     |.|:..|.|...:::.|.
  Fly   796 SAVDKISPSLKSPSGGSAYDSLDGGGSGSVSSAQPVAGGAGVPAAAAVALSTPTKSNGLALANGA 860

  Fly   234 DHF-----PESPLHSGGGFQLSPDFRQRASSNASSCGRLSPIRAQDLEPDWGFPVDYQNTTMTQA 293
            ...     |.||  :|||              :.|..|..|....:|...:.   :.:..|:.|.
  Fly   861 SQATNAARPHSP--NGGG--------------SGSHARFDPYLFPNLSKAFR---NIREDTVGQP 906

  Fly   294 HAQ-AL-EELTG--------TMADELTLCNQQQQGFSAASGLPSQPPPPPYQPPQHQQAQQQQQQ 348
            ..| || :||:|        ....:.........|.:.:.|:.|.
  Fly   907 MLQDALDDELSGDYHNNNNNNSGSKYNYMGANGSGGAGSGGVGSN-------------------- 951

  Fly   349 QSPYALNGPASGYNTLQPQSQCLLHRSLNCSCMHNARDGLSPNSVTTTMSPAYPN-------SEP 406
                 .||.:.|.|..:....|   .:.:...:|.|...|.........|..:.|       |.|
  Fly   952 -----ANGASDGINFARLARDC---GADSIDDVHAAAAMLYLKHGPKIYSEPFQNGSGPVITSSP 1008

  Fly   407 SSDSLNTYS---NVVLDGPADT------AALMVQQQQQQQQQQQLSASLEDNNCASTLIGQCLEV 462
            |.|  :|||   |...|..:.|      |...|.|...|.|..|..|. .|:||||
  Fly  1009 SED--HTYSAGGNSNADSGSSTPLTNGNALASVAQAVAQGQNNQGGAG-SDSNCAS--------- 1061

  Fly   463 LNNEAQPIDEFNLENFPVGNLECNVEELLQQEMSYGGLLDINIPLATVNTNLVNSSSGPLSISNI 527
             ::.|....|.|....|        ||:..::....|   ::..|:...:::|...    |::..
  Fly  1062 -SDAAYDSSEENHNITP--------EEMADRQRHRDG---VDALLSLSGSSIVECG----SVATT 1110

  Fly   528 SNLSNISSNSGSSLSLNQLQA---QLQQQQQQQQAQQQQQAQQQQQQHQQHQQQLLLNN---NNN 586
            ...||  .:||||......:|   .|:::..||..:||.|.|||||||  |.||...:.   .|.
  Fly  1111 HYHSN--GSSGSSHGSPHKRASSHSLEEEHLQQHREQQLQQQQQQQQH--HHQQFGSSQAVYTNG 1171

  Fly   587 SSSSLELATQTATTNLNARVQYSQ 610
            |.|.:.|.:..|.....|:.|..|
  Fly  1172 SGSKMALLSSAAANVALAQQQQQQ 1195

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
foxo	NP_650330.3	FH_FOXO	96..175	CDD:410806	34/94 (36%)
CHES-1-like	NP_511071.3	FH_FOXN2-like	700..775	CDD:410805	33/79 (42%)