Protein Alignment foxo and Foxs1

DIOPT Version :10

• Sequence 1: NP_650330.3
• Gene: foxo / 41709
• FlyBaseID: FBgn0038197
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: NP_001012091.1
• Gene: Foxs1 / 311547
• RGDID: 1310679
• Length: 327
• Species: Rattus norvegicus
• Alignment Length: 350
• Identity: 89/350 - (25%)
• Similarity: 132/350 - (37%)
• Gaps: 102/350 - (29%)

  Fly    99 SYADLITHAIGSATDKRLTLSQIYEWMVQNVPYFKDKGDSNSSAGWKNSIRHNLSLHNRFMRVQN 163
            ||..||..||.|:..:|.|||.||.:::....:::     ::..||:|||||||||:..|::|..
  Rat    22 SYIALIAMAIQSSPGQRATLSGIYRYIMGRFAFYR-----HNRPGWQNSIRHNLSLNECFVKVPR 81

  Fly   164 EG--TGKSSWWMLNPEA----KPGKSVRRRAASMETSRYEKRRGR--AKKRVEALRQAGVVGLND 220
            :.  .||.|:|.|:|:.    :.|..:|||      .|:.||.|.  .|..|:|          |
  Rat    82 DDRKPGKGSYWTLDPDCHDMFQHGSFLRRR------RRFTKRTGAQGTKGPVKA----------D 130

  Fly   221 ATPSPSSSVSEGLDHF---------PESPLHSG-GGFQLSPDFRQRASSNASSCGRLSPIRAQDL 275
            ..|..::|..:|..:.         ||.|...| ||..        .|..|:.|...|..|.|
  Rat   131 HRPLRATSPDQGAPNTTTGRLCPFPPEVPNPKGFGGLM--------GSLPANMCPTTSDTRPQ-- 185

  Fly   276 EPDWGFPVDYQNTTMTQAHAQALEELTGTMADELTLCNQQQQGFSAASGLPSQPPPPPYQPPQHQ 340
                 .|...::  |..|.:....||:...:............||.|..|...|.|
  Rat   186 -----LPTGPKD--MCSAKSGGPRELSEATSPSPCPAFGFSSAFSEAESLGKAPTP--------- 234

  Fly   341 QAQQQQQQQSPYALNGPASGYNTLQPQS-----QCLLHRSLNCSCMHNARDGLSPNSVTTTMSPA 400
                                  ::.|:|     ||.: ::|| .|| .|..||.....:...:|.
  Rat   235 ----------------------SVAPESIGSSYQCRM-QTLN-FCM-GADPGLEHLLTSAVATPG 274

  Fly   401 YPNSEPSSDSLNTYSNVVLDGPADT 425
              :|.||:.     ....|..|||:
  Rat   275 --SSTPSAS-----HRAPLPLPADS 292

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
foxo	NP_650330.3	FH_FOXO	96..175	CDD:410806	30/77 (39%)
Foxs1	NP_001012091.1	FH_FOXS1	17..116	CDD:410811	37/104 (36%)