Protein Alignment foxo and Foxe3

DIOPT Version :10

• Sequence 1: NP_650330.3
• Gene: foxo / 41709
• FlyBaseID: FBgn0038197
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: NP_056573.1
• Gene: Foxe3 / 30923
• MGIID: 1353569
• Length: 288
• Species: Mus musculus
• Alignment Length: 348
• Identity: 83/348 - (23%)
• Similarity: 114/348 - (32%)
• Gaps: 107/348 - (30%)

  Fly    25 GGDLPLDVGFEPQTRARSNTWPCPRPENFV-----EPTDELDSTKASNQQLAPGDSQQAIQNANA 84
            |..||...|.||..          .||..|     |||            ..||..::..:....
Mouse    20 GPQLPTLAGAEPGR----------EPEEVVGGGDAEPT------------AVPGPGKRRRRPLQR 62

  Fly    85 AKKNSSRRNAWGNLSYADLITHAIGSATDKRLTLSQIYEWMVQNVPYFKDKGDSNSSAGWKNSIR 149
            .|.         ..||..||..|:..|..:||||:.||.::.:...:::|     |...|:||||
Mouse    63 GKP---------PYSYIALIAMALAHAPGRRLTLAAIYRFITERFAFYRD-----SPRKWQNSIR 113

  Fly   150 HNLSLHNRFMRVQNE--GTGKSSWWMLNPEAKPGKSVRRRAASMETSRYEKRRGRAKKRVEALRQ 212
            |||:|::.|::|..|  ..||.::|.|:|.|         |...:...:.:||.|. ||.|.
Mouse   114 HNLTLNDCFVKVPREPGNPGKGNYWTLDPAA---------ADMFDNGSFLRRRKRF-KRAEL--- 165

  Fly   213 AGVVGLNDATPSPSSSVSEGLDHFPESPLHSGGGFQLSPDFRQRASSNASSCGRLSPIRAQDLEP 277
                   .|.|.|...       ||.:|.         |.....||:..:...||..:.....||
Mouse   166 -------PAPPPPPPP-------FPYAPF---------PPPPAPASAPPARLFRLDSLLGLQPEP 207

  Fly   278 DWGFPVDYQNTTMTQAHAQALEELTGTMADELTLCNQQQQGFSAASGLPSQPPPPPYQPPQHQQA 342
                                    .|.:|.|...|......|...:...|   ||.|.|...:..
Mouse   208 ------------------------PGPVAPEPPCCAAPDAAFPPCAAAAS---PPLYSPASERLG 245

  Fly   343 QQQQQQQSP-YALNGPASGYNTL 364
            ........| .||.|.|.....|
Mouse   246 LPAPLPAQPLLALAGSAGALGPL 268

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
foxo	NP_650330.3	FH_FOXO	96..175	CDD:410806	29/80 (36%)
Foxe3	NP_056573.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..62		14/63 (22%)
		FH_FOXE	64..152	CDD:410793	34/110 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	163..189		9/51 (18%)