Protein Alignment foxo and foxa

DIOPT Version :10

• Sequence 1: NP_650330.3
• Gene: foxo / 41709
• FlyBaseID: FBgn0038197
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: NP_571357.2
• Gene: foxa / 30539
• ZFINID: ZDB-GENE-990415-76
• Length: 355
• Species: Danio rerio
• Alignment Length: 329
• Identity: 86/329 - (26%)
• Similarity: 136/329 - (41%)
• Gaps: 81/329 - (24%)

  Fly    25 GGD-LPLDV-GFEPQTRARSNTWPCPRPENFVEPTD-ELDSTKASNQ--------QLAPGDSQQA 78
            |.| |||.. |:.|             ||:..:... :.||..|.|.        .|.|.:..:|
Zfish    24 GSDSLPLGPRGYSP-------------PEHHYQSYGVQCDSAPAVNPGRLGSPAGLLPPANPPKA 75

  Fly    79 IQNANAAK------KNSSRR---NAWGNLSYADLITHAIGSATDKRLTLSQIYEWMVQNVPYFKD 134
            ....|:::      |:..||   :|....||..||..||..:..|||||::||:|:.|..||::
Zfish    76 YAEINSSEPEFQELKSVYRRTLSHAKPPYSYISLICMAIQQSPAKRLTLNEIYDWIRQLFPYYR- 139

  Fly   135 KGDSNSSAGWKNSIRHNLSLHNRFMRVQN--EGTGKSSWWMLNPEA----KPGKSVRR------- 186
                .:...|:|||||:||.::.|:||..  :..||.|:|.|:|::    :.|..:||
Zfish   140 ----QNQQRWQNSIRHSLSFNDCFVRVPRSPDSPGKGSYWALHPDSGNMFENGCYMRRQKRFKCQ 200

  Fly   187 ------RAASMETSRYEKRRGRAKKRVEALRQAGVVGLNDATPSPSSSVSEGLDHFPESPLHSGG 245
                  :.:..|..:.||::.:..|.|.:.:..    .:|||...|::||.. :..|.||.|...
Zfish   201 KSTSTGKNSEGEDVKVEKKKKKEIKSVSSCKSP----TSDATKQSSTTVSYA-NTKPASPSHLNP 260

  Fly   246 GFQLSPDFRQRASSNASSCGRLSPIRAQ---DLEP-------------DWGF---PVDYQNTTMT 291
            ...|.|......|::..|.....|...:   ..||             |:.:   ||.|.....:
Zfish   261 SHTLFPTQPPEISTHLPSLSVPFPASMETSLHCEPSSQHQPISVPRLVDFQYCETPVSYPLYCQS 325

  Fly   292 QAHA 295
            .:||
Zfish   326 NSHA 329

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
foxo	NP_650330.3	FH_FOXO	96..175	CDD:410806	32/80 (40%)
foxa	NP_571357.2	FH_FOX	101..197	CDD:469596	37/100 (37%)