Protein Alignment foxo and Foxn4

DIOPT Version :10

• Sequence 1: NP_650330.3
• Gene: foxo / 41709
• FlyBaseID: FBgn0038197
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: NP_001376188.1
• Gene: Foxn4 / 288736
• RGDID: 1306389
• Length: 572
• Species: Rattus norvegicus
• Alignment Length: 510
• Identity: 107/510 - (20%)
• Similarity: 172/510 - (33%)
• Gaps: 175/510 - (34%)

  Fly    10 PRLTHTDNGLAMDQLGGDLPLDVGFEPQTRARSNTWPCPRPENFVEPTDELDSTKASNQQL---- 70
            |.:.|...|    .:.|.....||..|:...||.|...||....:.|   :.|.:||.:|:
  Rat   121 PSVPHPHPG----AMAGVADPHVGAAPRPMLRSQTAMVPRGMLGLSP---IGSYRASAEQMNQFP 178

  Fly    71 APGDSQQAIQN--------------ANAAKKNSSRRNAWGN------------------------ 97
            ..|.|...:|.              ..:..:.....:.:|:
  Rat   179 VGGQSSSGLQEMPQLYSPATQIQFPLPSGSQQCPPTSLYGSPFAARPPYPQAHVTVHSPQEAHPK 243

  Fly    98 ------LSYADLITHAIGSATDKRLTLSQIYEWMVQNVPYFKDKGDSNSSAGWKNSIRHNLSLHN 156
                  .||:.||..|:.|:....|.:|:||.:|.::.||||...|     |||||:||||||:.
  Rat   244 HYPKPIYSYSCLIAMALKSSKTGSLPVSEIYSFMKEHFPYFKTAPD-----GWKNSVRHNLSLNK 303

  Fly   157 RFMRVQNEGTG---KSSWWMLNP-------------EAKPGKSVRRRAASME------TSRYEKR 199
            .|.:|:.:.:|   |...|.||.             :.|...::.|..|:.|      :.|.|..
  Rat   304 CFEKVETKPSGSSRKGCLWALNLARIDKVEEEMHKWKRKDLAAIHRSMANPEELDKLISDRPESC 368

  Fly   200 RGRAKK---RVEALRQAGVV-------GLNDATPSPSSSVSEGLDHFPESPLHSGGGFQLSPDFR 254
            |...|:   .|..|.:|..|       .::...|.|..::|     ....|||    .|:.|...
  Rat   369 RRPGKQGEPEVPVLTRATTVAMTHSCLAISQLPPKPLMTLS-----LQSVPLH----HQVQPQAH 424

  Fly   255 QRASSNASSCGRLSPIRA-QDLEPD-------WGFPVDYQN-TTMTQAHAQALE------ELTGT 304
            ....|.|.:  :..|:.| .:|.|.       ...|.|:.| :|.|.....||:      .|.|.
  Rat   425 LAPDSPAPA--QTPPLHALPNLSPGPLPQPAVGRVPGDFLNISTDTNTEVDALDPSIMDFALQGN 487

  Fly   305 MADELTLCNQQQQGFSAAS-------------GLPSQPP-----PPPYQPPQHQQAQQQQQQQSP 351
            :.:|:     :::.||..:             |.||..|     ..|:...|
  Rat   488 LWEEM-----REESFSLDTLGAFGDSPLGCDLGTPSLTPVSGSGDQPFPDVQ------------- 534

  Fly   352 YALNGPASGYNTLQPQSQCLLHRSLNCSCMHNARDGLSPNSVTTTMSPAYPNSEP 406
              :.|..:.|:|:                   ..|.::|:.|.:......|.::|
  Rat   535 --VTGLYAAYSTV-------------------TADSVAPSVVNSAQYLGTPGNKP 568

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
foxo	NP_650330.3	FH_FOXO	96..175	CDD:410806	33/111 (30%)
Foxn4	NP_001376188.1	COG5025	<143..>357	CDD:227358	53/221 (24%)
		FH_FOX	242..347	CDD:469596	35/109 (32%)