Protein Alignment foxo and FOXR1

DIOPT Version :10

• Sequence 1: NP_650330.3
• Gene: foxo / 41709
• FlyBaseID: FBgn0038197
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: XP_016873064.1
• Gene: FOXR1 / 283150
• HGNCID: 29980
• Length: 297
• Species: Homo sapiens
• Alignment Length: 187
• Identity: 49/187 - (26%)
• Similarity: 79/187 - (42%)
• Gaps: 38/187 - (20%)

  Fly    34 FEPQTRARSNTWPCPRPENFVEPTDELDSTKASNQQLAPGDSQQAIQNANAAKKNSSRRNAWGN- 97
            |.|      :||.....|   |..|:.||   |:..|.....:..:|:....:.:|.....|..
Human   122 FSP------STWELTEEE---EAEDQEDS---SSMALPSPHKRAPLQSRRLRQASSQAGRLWSRP 174

  Fly    98 -LSYADLITHAIGSATDKRLTLSQIYEWMVQNVPYFKDKGDSNSSAGWKNSIRHNLSLHNRFMRV 161
             |:|..||..|:.:::...|.:.|||.:..::.|:|:     .:..||||::||||...:.|.:|
Human   175 PLNYFHLIALALRNSSPCGLNVQQIYSFTRKHFPFFR-----TAPEGWKNTVRHNLCFRDSFEKV 234

  Fly   162 QNEGTG------KSSWWMLNPEAKPGKSVRRRAASMETSRYEKRRGRAKKRVEALRQ 212
            .....|      :|..|.|..|.      .||.|       |:.|..|..|:|:::|
Human   235 PVSMQGGASTRPRSCLWKLTEEG------HRRFA-------EEARALASTRLESIQQ 278

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
foxo	NP_650330.3	FH_FOXO	96..175	CDD:410806	24/86 (28%)
FOXR1	XP_016873064.1	FH_FOXR	171..259	CDD:410810	27/98 (28%)