Protein Alignment foxo and FOXP1

DIOPT Version :10

• Sequence 1: NP_650330.3
• Gene: foxo / 41709
• FlyBaseID: FBgn0038197
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: NP_001231739.1
• Gene: FOXP1 / 27086
• HGNCID: 3823
• Length: 693
• Species: Homo sapiens
• Alignment Length: 347
• Identity: 84/347 - (24%)
• Similarity: 128/347 - (36%)
• Gaps: 97/347 - (27%)

  Fly    38 TRARSNTWPCPRPENFVEPTDELDS--------TKASNQQLAP-----GDSQQA-IQNANAAKKN 88
            :::.|...|...|.....||..|..        |..|...:.|     .|.... |.:|:.|:..
Human   392 SKSASEASPQSLPHTPTTPTAPLTPVTQGPSVITTTSMHTVGPIRRRYSDKYNVPISSADIAQNQ 456

  Fly    89 SSRRNAWGN--LSYADLITHAIGSATDKRLTLSQIYEWMVQNVPYFKDKGDSNSSAGWKNSIRHN 151
            ...:||...  .:||.||..||..:.:|:|||::||.|..:...||:     .::|.||.:||.|
Human   457 EFYKNAEVRPPFTYASLIRQAILESPEKQLTLNEIYNWFTRMFAYFR-----RNAATWKGAIRTN 516

  Fly   152 LSLHNRFMRVQNE-GTGKSSWWMLNPEAKPGKSVRRRAASMETSRYEKRRGRAKKRVEALRQAGV 215
            ||||..|:||::| |   |.|.:.:.|.|.|:.:              :|||.:|.
Human   517 LSLHKCFIRVEDEFG---SFWTVDDEEFKRGRHI--------------QRGRPRKY--------- 555

  Fly   216 VGLNDATPSPSSSVSEGLDHFPESPLHSGGGFQLSPDFRQRASSNASSCGRLSPIRA--QDLEPD 278
                    .|..:..|.:.|              :|...:...|:.:.|   :|:.|  |....:
Human   556 --------CPDENFDELVAH--------------NPSLIKNMQSSHAYC---TPLNAALQASMAE 595

  Fly   279 WGFPV----DYQNTTMTQAHAQALEELTGTMADELTLCNQQQQGFSAASGLPSQPPPPPYQP--P 337
            ...|:    ...|.|:....:...|||.|.|  |.|..|:..          |.|...|.|.  |
Human   596 NSIPLYTTASMGNPTLGNLASAIREELNGAM--EHTNSNESD----------SSPGRSPMQAVHP 648

  Fly   338 QHQQAQQQQQQQSPYALNGPAS 359
            .|    .:::...|....||.|
Human   649 VH----VKEEPLDPEEAEGPLS 666

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
foxo	NP_650330.3	FH_FOXO	96..175	CDD:410806	32/81 (40%)
FOXP1	NP_001231739.1	FOXP-CC	302..369	CDD:465036
		FH_FOX	464..545	CDD:469596	34/88 (39%)