Protein Alignment foxo and Foxa3

DIOPT Version :10

• Sequence 1: NP_650330.3
• Gene: foxo / 41709
• FlyBaseID: FBgn0038197
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: NP_001420666.1
• Gene: Foxa3 / 25100
• RGDID: 2809
• Length: 361
• Species: Rattus norvegicus
• Alignment Length: 278
• Identity: 64/278 - (23%)
• Similarity: 107/278 - (38%)
• Gaps: 90/278 - (32%)

  Fly    99 SYADLITHAIGSATDKRLTLSQIYEWMVQNVPYFKDKGDSNSSAGWKNSIRHNLSLHNRFMRVQN 163
            ||..|||.||..|..|.||||:||:|::...||:::     :...|:|||||:||.::.|::|..
  Rat   130 SYISLITMAIQQAPGKMLTLSEIYQWIMDLFPYYRE-----NQQRWQNSIRHSLSFNDCFVKVAR 189

  Fly   164 --EGTGKSSWWMLNPEA----KPGKSVRRRAASMETSRYEKRRGRAKKRVEALRQAGVVGLNDAT 222
              :..||.|:|.|:|.:    :.|..:||:    :..:.|::..:......|.|...|.....||
  Rat   190 SPDKPGKGSYWALHPSSGNMFENGCYLRRQ----KRFKLEEKAKKGNSATSATRNGTVGSATSAT 250

  Fly   223 PSPSSSVSEGLDHFPESPLHSGGGFQLSPDFRQRASSNASSCGRLSPIRAQDLEPDWGFPVDYQN 287
            .:.:::|:                                     ||.:.|...|
  Rat   251 TTAATAVT-------------------------------------SPAQPQPTPP---------- 268

  Fly   288 TTMTQAHAQALEELTGTMADELTLCNQQQQGFSAASGLPSQPPPPPYQPPQHQ--QAQQQQQQQS 350
               ::..||:.|::               .|...||        ||...|...  :...:.:..:
  Rat   269 ---SEPEAQSGEDV---------------GGLDCAS--------PPSSAPYFTGLELPGELKLDA 307

  Fly   351 PYALNGPASGYNTLQPQS 368
            ||..|.|.|..|.:..|:
  Rat   308 PYNFNHPFSINNLMSEQT 325

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
foxo	NP_650330.3	FH_FOXO	96..175	CDD:410806	32/77 (42%)
Foxa3	NP_001420666.1	FH_FOXA3	124..225	CDD:410814	37/103 (36%)