Protein Alignment foxo and FOXL1

DIOPT Version :10

• Sequence 1: NP_650330.3
• Gene: foxo / 41709
• FlyBaseID: FBgn0038197
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: NP_005241.1
• Gene: FOXL1 / 2300
• HGNCID: 3817
• Length: 345
• Species: Homo sapiens
• Alignment Length: 206
• Identity: 64/206 - (31%)
• Similarity: 96/206 - (46%)
• Gaps: 46/206 - (22%)

  Fly    99 SYADLITHAIGSATDKRLTLSQIYEWMVQNVPYFKDKGDSNSSAGWKNSIRHNLSLHNRFMRVQN 163
            ||..||..||..|.::|:||:.||::::...|::.|     :..||:|||||||||::.|::|..
Human    53 SYIALIAMAIQDAPEQRVTLNGIYQFIMDRFPFYHD-----NRQGWQNSIRHNLSLNDCFVKVPR 112

  Fly   164 E--GTGKSSWWMLNP----------------EAKPGKSVRRRAASMETSRYEKRRGRAKKRVEAL 210
            |  ..||.|:|.|:|                :.|||..    |...:..|.|..:..|:.:.||.
Human   113 EKGRPGKGSYWTLDPRCLDMFENGNYRRRKRKPKPGPG----APEAKRPRAETHQRSAEAQPEAG 173

  Fly   211 RQAG----VVGLNDATPSPSSSVSEGLDHFPESPLHSGGGFQLSP-----DFRQRASSNA----- 261
            ..||    .:....|.|:..|.:.:|..  |.:|||..|  ..||     |..|.|::.|
Human   174 SGAGGSGPAISRLQAAPAGPSPLLDGPS--PPAPLHWPG--TASPNEDAGDAAQGAAAVAVGQAA 234

  Fly   262 -SSCGRLSPIR 271
             :..|..||:|
Human   235 RTGDGPGSPLR 245

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
foxo	NP_650330.3	FH_FOXO	96..175	CDD:410806	32/77 (42%)
FOXL1	NP_005241.1	FH_FOXL1	47..144	CDD:410801	34/95 (36%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	136..289		30/118 (25%)