Protein Alignment foxo and Foxc2

DIOPT Version :10

• Sequence 1: NP_650330.3
• Gene: foxo / 41709
• FlyBaseID: FBgn0038197
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: NP_001095150.1
• Gene: Foxc2 / 171356
• RGDID: 621703
• Length: 494
• Species: Rattus norvegicus
• Alignment Length: 468
• Identity: 110/468 - (23%)
• Similarity: 168/468 - (35%)
• Gaps: 149/468 - (31%)

  Fly    99 SYADLITHAIGSATDKRLTLSQIYEWMVQNVPYFKDKGDSNSSAGWKNSIRHNLSLHNRFMRV-- 161
            ||..|||.||.:|.:|::||:.||::::...|::::     :..||:|||||||||:..|::|
  Rat    75 SYIALITMAIQNAPEKKITLNGIYQFIMDRFPFYRE-----NKQGWQNSIRHNLSLNECFVKVPR 134

  Fly   162 QNEGTGKSSWWMLNPEA----KPGKSVRRRAASMETSRYEKRRGRAKKRVEA-LRQ---AGVVGL 218
            .::..||.|:|.|:|::    :.|..:|||      .|::|:.....|...| |::   |...|.
  Rat   135 DDKKPGKGSYWTLDPDSYNMFENGSFLRRR------RRFKKKDVPKDKEERAHLKEPPPASAKGA 193

  Fly   219 NDATP-------------------SPSSSVSEGLDHF-PESPLHSGGGFQLSPDFRQRASSNASS 263
            ...||                   ||:..|...::.. ||      |..|.||  |..||:.|.|
  Rat   194 PTGTPVADGPKEAEKKVVVKSEAASPALPVITKVETLSPE------GALQASP--RSSASTPAGS 250

  Fly   264 CGRLSPIRAQDLEPDWGFPVDYQNTTMTQAHAQALEELTGTMADELTLCNQQQQG-----FSAAS 323
                         ||...|         :.||.|...|.|...:.:........|     .:|.:
  Rat   251 -------------PDGSLP---------EHHAAAPNGLPGFSVETIMTLRTSPPGGDLSPAAARA 293

  Fly   324 GLPSQP--------PPPPYQPPQHQ---------------------QAQQQQQQQSPYAL----- 354
            ||...|        ||..|..|..|                     .|::......|.||
  Rat   294 GLVVPPLALPYAAAPPAAYAQPCAQGLEAAGSAGYQCSMRAMSLYTGAERPAHVCVPPALDEALS 358

  Fly   355 ---NGPASGYNTLQPQSQCLLHRSLNCSCMHNARDG-LSPNSVTTTMSPAYPNSEPSSDSLNTYS 415
               :||.|....|...:.  ...:|..|..|:.... |.|.:......|. |..:|::.:.:.|.
  Rat   359 DHPSGPGSPLGALNLAAG--QEGALGASGHHHQHHSHLHPQAPPPAPQPP-PAPQPATQATSWYL 420

  Fly   416 NVVLDG------PADTAALMVQQQQQQQQQQQLSASLEDNNCASTLIGQCLEVLNNEAQPIDEFN 474
            |   .|      |..|.|          .|||...::.             |:.|:....:|...
  Rat   421 N---HGGDLSHLPGHTFA----------TQQQTFPNVR-------------EMFNSHRLGLDNST 459

  Fly   475 LENFPVGNLECNV 487
            |....|.|..|.:
  Rat   460 LGESQVSNASCQL 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
foxo	NP_650330.3	FH_FOXO	96..175	CDD:410806	31/77 (40%)
Foxc2	NP_001095150.1	FH_FOXC1	66..158	CDD:410818	33/87 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	166..213		9/46 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	233..267		16/63 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	380..422		10/45 (22%)