Protein Alignment foxo and Foxn2

DIOPT Version :10

• Sequence 1: NP_650330.3
• Gene: foxo / 41709
• FlyBaseID: FBgn0038197
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: NP_851305.2
• Gene: Foxn2 / 14236
• MGIID: 1347478
• Length: 429
• Species: Mus musculus
• Alignment Length: 312
• Identity: 72/312 - (23%)
• Similarity: 115/312 - (36%)
• Gaps: 93/312 - (29%)

  Fly    83 NAAKKNSSRRNAWGNLSYADLITHAIGSATDKRLTLSQIYEWMVQNVPYFKDKGDSNSSAGWKNS 147
            |..||:::.:..:   |::.||..||..:.:|.|.:.:||.|::...|||     :.:..|||||
Mouse   103 NPEKKSATSKPPY---SFSLLIYMAIEHSPNKCLPVKEIYSWILDRFPYF-----ATAPTGWKNS 159

  Fly   148 IRHNLSLHNRFMRVQ---NEGTGKSSWWMLNPEAKPG--KSVRRRAAS----------------- 190
            :||||||:..|.:|:   .:..||.|.|.::||.||.  ::::::..|
Mouse   160 VRHNLSLNKCFQKVERSHGKVNGKGSLWCVDPEYKPNLMQALKKQPFSSPQSAALSPHCLSSALK 224

  Fly   191 --------------------------METSRYEK----RRGRAKKRV--EALRQAGVVGLNDATP 223
                                      .|....||    :....|||.  .|....|.|.|.: :|
Mouse   225 QSQVQTLQESDIDAATAMILLNTSIEQEILECEKPLPLKTSLQKKRSYGSAFSAPGAVRLQE-SP 288

  Fly   224 SPSSSVSEGLDHFPESPLHSGGGFQLSPDFRQRASSNASSCGRLSPIRAQDLEP---------DW 279
            ||::.:....||          .:..:....||.:|.||.....|.....:..|         ..
Mouse   289 SPTAGIDPKADH----------NYSANSVAAQRCASRASMSSLSSVDEVYEFIPKSSHGGSDGSE 343

  Fly   280 GFPVDYQNTTMTQAHAQALEELTGTMADELTLCNQQQQGFSAASGLPSQPPP 331
            ||..|      .:..|:..|:..|...     ...|.:|.|...|.|.:..|
Mouse   344 GFHSD------EETDAEDEEDPLGDSG-----YAPQARGHSTLKGQPGKKIP 384

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
foxo	NP_650330.3	FH_FOXO	96..175	CDD:410806	30/81 (37%)
Foxn2	NP_851305.2	FH_FOXN2	111..192	CDD:410832	30/88 (34%)