Protein Alignment foxo and Foxc2

DIOPT Version :10

• Sequence 1: NP_650330.3
• Gene: foxo / 41709
• FlyBaseID: FBgn0038197
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: NP_038547.2
• Gene: Foxc2 / 14234
• MGIID: 1347481
• Length: 494
• Species: Mus musculus
• Alignment Length: 460
• Identity: 105/460 - (22%)
• Similarity: 166/460 - (36%)
• Gaps: 133/460 - (28%)

  Fly    99 SYADLITHAIGSATDKRLTLSQIYEWMVQNVPYFKDKGDSNSSAGWKNSIRHNLSLHNRFMRV-- 161
            ||..|||.||.:|.:|::||:.||::::...|::::     :..||:|||||||||:..|::|
Mouse    75 SYIALITMAIQNAPEKKITLNGIYQFIMDRFPFYRE-----NKQGWQNSIRHNLSLNECFVKVPR 134

  Fly   162 QNEGTGKSSWWMLNPEA----KPGKSVRRRAASMETSRYEKR--------RGRAKK--------- 205
            .::..||.|:|.|:|::    :.|..:|||      .|::|:        |...|:
Mouse   135 DDKKPGKGSYWTLDPDSYNMFENGSFLRRR------RRFKKKDVPKDKEERAHLKEPPSTTAKGA 193

  Fly   206 --------------------------------RVEALRQAGVVGLNDATPSPSSSVSEGL----- 233
                                            :||.|...|.:   .|:|..:||...|.
Mouse   194 PTGTPVADGPKEAEKKVVVKSEAASPALPVITKVETLSPEGAL---QASPRSASSTPAGSPDGSL 255

  Fly   234 -DHFPESPLHSGGGFQLSPDFRQRASSNASSCGRLSP--IRAQDLEPDWGFP-VDYQNTTMTQAH 294
             :|...:| :...||.:......|.|...   |.|||  .||..:.|....| ........||..
Mouse   256 PEHHAAAP-NGLPGFSVETIMTLRTSPPG---GDLSPAAARAGLVVPPLALPYAAAPPAAYTQPC 316

  Fly   295 AQALEELTGTMADELTLCNQQQQGFSAASGLPSQPPPPPYQPPQHQQAQQQQQQQSPYALNGPAS 359
            ||.| |..|:...:   |:.:.......:..|:....||        |..:.....|.....|..
Mouse   317 AQGL-EAAGSAGYQ---CSMRAMSLYTGAERPAHVCVPP--------ALDEALSDHPSGPGSPLG 369

  Fly   360 GYNTLQPQSQCLLHRSLNCSCMHNARDG-LSPNSVTTTMSPAYPNSEPSSDSLNTYSNVVLDG-- 421
            ..|....|     ..:|..|..|:...| |.|.:......|. |..:|::.:.:.|.|   .|
Mouse   370 ALNLAAGQ-----EGALGASGHHHQHHGHLHPQAPPPAPQPP-PAPQPATQATSWYLN---HGGD 425

  Fly   422 ----PADTAALMVQQQQQQQQQQQLSASLEDNNCASTLIGQCLEVLNNEAQPIDEFNLENFPVGN 482
                |..|.|          .|||...::.             |:.|:....:|..:|....|.|
Mouse   426 LSHLPGHTFA----------TQQQTFPNVR-------------EMFNSHRLGLDNSSLGESQVSN 467

  Fly   483 LECNV 487
            ..|.:
Mouse   468 ASCQL 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
foxo	NP_650330.3	FH_FOXO	96..175	CDD:410806	31/77 (40%)
Foxc2	NP_038547.2	FH_FOXC1	66..158	CDD:410818	33/87 (38%)
		COG5025	71..>251	CDD:227358	50/189 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	166..213		4/46 (9%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	233..267		8/37 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	381..422		11/44 (25%)