Protein Alignment foxo and Foxn4

DIOPT Version :10

• Sequence 1: NP_650330.3
• Gene: foxo / 41709
• FlyBaseID: FBgn0038197
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: NP_683737.2
• Gene: Foxn4 / 116810
• MGIID: 2151057
• Length: 521
• Species: Mus musculus
• Alignment Length: 525
• Identity: 113/525 - (21%)
• Similarity: 174/525 - (33%)
• Gaps: 182/525 - (34%)

  Fly     6 AQEWPRLTHTDNGLAMD------------QLGGDLPLDVGFEPQ-TRARSNTWPCPRPENFVEPT 57
            |.:.|||....|| .:|            .|.|...|.||..|: ...||.|...||....:.|
Mouse    51 AVDVPRLQQMANG-RIDLGSSGVTHPHPGALAGTADLHVGAAPRPLLRRSQTAVVPRGVLGLSP- 113

  Fly    58 DELDSTKASNQQL----APGDSQQAIQN----------------------------ANAAKKNSS 90
              :.:.:||.:|:    |.|.:...:|.                            .:......|
Mouse   114 --IGNHRASAEQMNQFPAGGQASSGLQEMPQLYSPATQIPFPLPLGSQQCPPAGLYGSPFSARPS 176

  Fly    91 RRNAWGNL----------------SYADLITHAIGSATDKRLTLSQIYEWMVQNVPYFKDKGDSN 139
            ...|.|.:                ||:.||..|:.::....|.:|:||.:|.::.||||...|
Mouse   177 YPQAHGAMHASQEPHPKHYPKPIYSYSCLIAMALKNSKTGSLPVSEIYSFMKEHFPYFKTAPD-- 239

  Fly   140 SSAGWKNSIRHNLSLHNRFMRVQNEGTG---KSSWWMLN------PEAKPGKSVRRRAASM---- 191
               |||||:||||||:..|.:|:.:.:|   |...|.||      .|.:..|..|:..|::
Mouse   240 ---GWKNSVRHNLSLNKCFEKVETKSSGSSRKGCLWALNLARIDKMEEEMHKWKRKDLAAIHRSM 301

  Fly   192 --------------ETSRYEKRRGRAKKRVEALRQAGVV-------GLNDATPSPSSSVSEGLDH 235
                          |:.|...:||..|  ...|..|..|       .::...|.|..::|
Mouse   302 ANPEELDKLISDRPESCRRPGKRGEPK--APMLTHATTVAMAHSCLAISQLPPKPLMTLS----- 359

  Fly   236 FPESPLHSGGGFQLSPDFRQRASSNASSCGRLSPIRAQDL-------EPDWG-FPVDYQN-TTMT 291
            ....|||    .||.|.......|.|.:  :..|:.|...       :|..| .|.|:.| .:..
Mouse   360 LQSVPLH----HQLQPQAHLAPDSPAPA--QTPPLHALPSLSPGPLPQPAMGRVPGDFLNINSDM 418

  Fly   292 QAHAQALE------ELTGTMADELTLCNQQQQGFSAAS-------------GLPSQPPPPPYQPP 337
            .....||:      .|.|.:.:|:     ::..||..:             |.||..|
Mouse   419 NTEVDALDPSIMDFALQGNLWEEM-----KEDSFSLDTLEAFGDSPLGCDLGAPSLTP------- 471

  Fly   338 QHQQAQQQQQQQSP-YALNGPASGYNTLQPQSQCLLHRSLNCSCMHNARDGLSPNSVTTTMSPAY 401
                ......|..| ..:.|..:.|:|                    |.||::|::..:......
Mouse   472 ----VSGNSDQSFPDVQVTGLYAAYST--------------------AADGVAPSAANSAQYLGT 512

  Fly   402 PNSEP 406
            |.::|
Mouse   513 PGNKP 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
foxo	NP_650330.3	FH_FOXO	96..175	CDD:410806	32/97 (33%)
Foxn4	NP_683737.2	FH_FOX	192..297	CDD:469596	37/109 (34%)
		FAM75	321..>401	CDD:464237	19/92 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	371..406		6/36 (17%)