Protein Alignment foxo and foxc1a

DIOPT Version :10

• Sequence 1: NP_650330.3
• Gene: foxo / 41709
• FlyBaseID: FBgn0038197
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: NP_571803.1
• Gene: foxc1a / 100148408
• ZFINID: ZDB-GENE-010302-1
• Length: 476
• Species: Danio rerio
• Alignment Length: 452
• Identity: 106/452 - (23%)
• Similarity: 167/452 - (36%)
• Gaps: 148/452 - (32%)

  Fly    39 RARSNTWPCPRPENFVEPTDELDSTKASNQQLAPGDSQQAIQNANAAKKNSSRRNAWGNLSYADL 103
            ||.....|.|:|::.|:|.                                        .||..|
Zfish    58 RAYGPYTPQPQPKDMVKPP----------------------------------------YSYIAL 82

  Fly   104 ITHAIGSATDKRLTLSQIYEWMVQNVPYFKDKGDSNSSAGWKNSIRHNLSLHNRFMRV--QNEGT 166
            ||.||.::.||::||:.||:::::..|:::|     :..||:|||||||||:..|::|  .::..
Zfish    83 ITMAIQNSPDKKVTLNGIYQFIMERFPFYRD-----NKQGWQNSIRHNLSLNECFVKVPRDDKKP 142

  Fly   167 GKSSWWMLNPEAKPGKSVRRRAASMETSRYEKRRGRAKKRVEALRQAGVVGLNDATPSPSSSVSE 231
            ||.|:|.|:|::         ....|...:.:||.|.||: :|::.....|:.:|   ||.
Zfish   143 GKGSYWTLDPDS---------YNMFENGSFLRRRRRFKKK-DAMKDKEDRGVKEA---PSR---- 190

  Fly   232 GLDHFPESPLHSGGGFQLSPDFRQRASSNASSCGRLSPIRAQDLEPDWGFPVDYQNTTMTQAHAQ 296
                            |..|..|::..|...|    .|:|.||::.:.|          |....|
Zfish   191 ----------------QAQPQAREQEQSVPGS----QPVRIQDIKTENG----------TSTPPQ 225

  Fly   297 ALEELTGTMADELTLCNQQQQGFSAASGLPSQPPPP-----PYQPPQHQQAQQQQQQQSPYALNG 356
            |:.....|:..    ........|.:||.|...|..     .....||.||
Zfish   226 AVSPTLSTVPK----IESPDSSSSMSSGSPHSIPSTRSLSLDSAGEQHHQA-------------- 272

  Fly   357 PASGY--NTLQPQSQCLLHRS--LNCSCMHNARDGLSPNSVTTTMSPAY-PN-----SEP-SSDS 410
            ||.|:  :.:....:...|.|  |..|.:..:|.|::|     |:|..| ||     |.| |.:|
Zfish   273 PAQGFSVDNIMTSLRGSPHSSGELTPSLVAPSRTGITP-----TLSLNYSPNQSSVYSSPCSQNS 332

  Fly   411 LNTYSNVVL---------------DGPADTAALMVQQQQQQQQQQQLSASLEDNNCASTLIG 457
            ::|.||...               .|...|.|..|.:..........::||...|.:|...|
Zfish   333 ISTTSNATYHCNMQAMSLYAGGDRSGHLGTTATTVDETLPDYSITTTTSSLSHGNLSSAQEG 394

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
foxo	NP_650330.3	FH_FOXO	96..175	CDD:410806	32/80 (40%)
foxc1a	NP_571803.1	FH_FOXC1	69..161	CDD:410818	38/145 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	169..271		29/143 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	284..303		4/18 (22%)