Protein Alignment foxo and foxf2b

DIOPT Version :10

• Sequence 1: NP_650330.3
• Gene: foxo / 41709
• FlyBaseID: FBgn0038197
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: XP_003200754.1
• Gene: foxf2b / 100002904
• ZFINID: ZDB-GENE-041001-130
• Length: 429
• Species: Danio rerio
• Alignment Length: 478
• Identity: 108/478 - (22%)
• Similarity: 179/478 - (37%)
• Gaps: 144/478 - (30%)

  Fly    19 LAMDQLGGDLPL--DVG-FEPQTRARSNTWPCPRPENFVEPTDELDSTKASNQQL--APGDSQQA 78
            |::|.||..||.  |.| |...|.....|.....|.....||....:|.|.:..|  :.|:.::.
Zfish    29 LSIDPLGFALPFSSDNGLFSYVTAGPMTTESSHGPLGSTPPTRTSPATTALHPGLMNSTGNLEEH 93

  Fly    79 IQNANAAKKNSS-RRNAWGNLSYADLITHAIGSATDKRLTLSQIYEWMVQNVPYFKDKGDSNSSA 142
            ...:.:.|.||. ||......||..||..||.||..||||||:||:::....|:|:     .|..
Zfish    94 SAVSKSKKTNSGLRRPEKPPYSYIALIVMAIQSAPTKRLTLSEIYQFLQTRFPFFR-----GSYQ 153

  Fly   143 GWKNSIRHNLSLHNRFMRVQNEG---TGKSSWWMLNPEAKPGKSVRRRAASMETSRYEKRRGRAK 204
            |||||:||||||:..|:::. :|   .||..:|.::|.::         ...|...:.:|....:
Zfish   154 GWKNSVRHNLSLNECFIKLP-KGLGRPGKGHYWTIDPTSE---------FMFEEGSFRRRPRGFR 208

  Fly   205 KRVEALRQAGVVGLNDATPSPSSSVSEGLDHFPESPLHSGGGFQLSPDFRQRASSNASSCGRLSP 269
            ::.:|::             |...:..||          |.|..:.|.
Zfish   209 RKCQAMK-------------PMYRMMNGL----------GFGSAILPQ----------------- 233

  Fly   270 IRAQDLEPDWGFPVDYQNTTMTQA-HAQALE-ELTGTMADELT------LCNQQQQGFSAASGLP 326
                        ..|||:.|...| |:.... :|:|:..:.::      :....:.|:.::..:|
Zfish   234 ------------SFDYQSPTGALACHSSGYNLDLSGSGYESISSGHHGHMSPSSRHGYMSSCPMP 286

  Fly   327 --------SQPPPPPYQPPQHQQAQQQQQQQSPYALNGPASGYNTLQPQSQ-CLLHRSLNCSCMH 382
                    |...|.|..|                |:.|...|::   |.|: ..|..|.|.|.:.
Zfish   287 GNGDYAVESNTSPVPSSP----------------AVAGALEGHS---PYSESTALWASSNSSYLK 332

  Fly   383 NARDGLSPNSVTTTMSPAYPNSEPSSD--SLNTYSNVVLDGPADTAALMVQQ---QQQQQQQQQL 442
            .|      |::|:       ||:|:..  .:.|||              ::|   ||..:....:
Zfish   333 QA------NTITS-------NSQPTGQHPGIFTYS--------------LEQGYIQQSARDNADM 370

  Fly   443 SASLEDNNCASTLIGQCLEVLNN 465
            |..|......|:.:|:..:.:.|
Zfish   371 SVGLSRYPTHSSPVGERKDFMLN 393

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
foxo	NP_650330.3	FH_FOXO	96..175	CDD:410806	35/81 (43%)
foxf2b	XP_003200754.1	FH_FOXF1	112..210	CDD:410823	38/112 (34%)