DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG3061 and DNAJB14

DIOPT Version :10

Sequence 1:NP_650328.1 Gene:CG3061 / 41707 FlyBaseID:FBgn0038195 Length:370 Species:Drosophila melanogaster
Sequence 2:NP_001026893.1 Gene:DNAJB14 / 79982 HGNCID:25881 Length:379 Species:Homo sapiens


Alignment Length:383 Identity:154/383 - (40%)
Similarity:230/383 - (60%) Gaps:29/383 - (7%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MDGNKDEAQRCIDFAVQALAAGKIEKAEKFLLKAERLFPTDNAKKLLAQLKSTPSNESNGK--SR 63
            |:||:|||::|::.|.:||.||..|||::||.|||:|:|..:|:.||..:....|...|..  .:
Human     1 MEGNRDEAEKCVEIAREALNAGNREKAQRFLQKAEKLYPLPSARALLEIIMKNGSTAGNSPHCRK 65

  Fly    64 TAGASDEKDSGPRKRVNSDSRSSAPDYTKDQLEAVRKVKTCKDYYEVLGVSKTATDSEIKKAYKK 128
            .:|:.|:......|...|.|......|||||::.|..:..||:|||||||:|.|.|.::||||:|
Human    66 PSGSGDQSKPNCTKDSTSGSGEGGKGYTKDQVDGVLSINKCKNYYEVLGVTKDAGDEDLKKAYRK 130

  Fly   129 LALQLHPDKNKAPGAVEAFKALGNAAGVLTDAEKRKNYDLYGINESHNGHGNNGGGHHGHGQYYN 193
            |||:.|||||.||||.:|||.:|||..||::.||||.|||.|..|....|.|||           
Human   131 LALKFHPDKNHAPGATDAFKKIGNAYAVLSNPEKRKQYDLTGNEEQACNHQNNG----------- 184

  Fly   194 NEYGYSRGFQADISAEELFNMFFNGGFPQQNVH-----------MRQQRRRQQAREDREGNNS-S 246
             .:.:.||.:|||:.|:|||:||.||||..:||           ..|.|.....||:..|:.. |
Human   185 -RFNFHRGCEADITPEDLFNIFFGGGFPSGSVHSFSNGRAGYSQQHQHRHSGHEREEERGDGGFS 248

  Fly   247 ALVNLLPIVLLIGLSMMSSFFISDPMYSLTP--SHKYSVKRETNSLKVPYYVKDNFYSEYQGS-V 308
            ..:.|:||::||.:|::|...:|:|.|||.|  ....::|.:|.:|.|.|||..:|.:||:|. :
Human   249 VFIQLMPIIVLILVSLLSQLMVSNPPYSLYPRSGTGQTIKMQTENLGVVYYVNKDFKNEYKGMLL 313

  Fly   309 ARLEESVEEDFVNHLKHSCSRERNYRDSMLAKARTFGDRDLYRKAQNINTPSCENLQK 366
            .::|:|||||:|.:::::|.:||..:..|...|:.:.|..|.|||..::..:|:.|::
Human   314 QKVEKSVEEDYVTNIRNNCWKERQQKTDMQYAAKVYRDDRLRRKADALSMDNCKELER 371

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG3061NP_650328.1 DnaJ_bact 106..>220 CDD:274090 60/113 (53%)
DUF1977 264..364 CDD:462754 36/102 (35%)
DNAJB14NP_001026893.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 55..94 8/38 (21%)
DnaJ_bact 109..>214 CDD:274090 63/116 (54%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 219..241 4/21 (19%)
DUF1977 271..369 CDD:462754 35/97 (36%)

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