DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3061 and dnajb14

DIOPT Version :9

Sequence 1:	NP_650328.1	Gene:	CG3061 / 41707	FlyBaseID:	FBgn0038195	Length:	370	Species:	Drosophila melanogaster
Sequence 2:	NP_001071255.1	Gene:	dnajb14 / 792752	ZFINID:	ZDB-GENE-061110-138	Length:	380	Species:	Danio rerio

Alignment Length:	383	Identity:	152/383 - (39%)
Similarity:	235/383 - (61%)	Gaps:	28/383 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDGNKDEAQRCIDFAVQALAAGKIEKAEKFLLKAERLFPTDNAKKLLAQLKSTPSNESNGKSRTA 65
            |:||:|||::|::.||:|:..|...||.|||.|||:|:||:.||.||..|.:..::..|..:...
Zfish     1 MEGNRDEAKKCLNIAVKAIEDGNKNKALKFLYKAEKLYPTEKAKVLLEALLNNGNSTGNSTAYCG 65

  Fly    66 GASDEKDSGPRKRVNSDSRSSA-----PDYTKDQLEAVRKVKTCKDYYEVLGVSKTATDSEIKKA 125
            .:|:....|.:.:..:..:.||     ..:||:|.|.|:::|.||:||||||:.|.|:|.|:|||
Zfish    66 KSSNGSKPGSQTQHEAPKQDSAAADLTKGFTKEQAEGVQRIKKCKNYYEVLGIRKDASDDELKKA 130

  Fly   126 YKKLALQLHPDKNKAPGAVEAFKALGNAAGVLTDAEKRKNYDLYGINESHNGHGNNGGGHHGHGQ 190
            |::|||:.|||||.||||.:|||.:|||..||::.||::.|||.|..|...   .|...|.|
Zfish   131 YRQLALKFHPDKNHAPGATDAFKKIGNAYSVLSNPEKKRQYDLSGGEEPST---PNYSSHEG--- 189

  Fly   191 YYNNEYGYSRGFQADISAEELFNMFFNGGFPQQNVH---------MRQQRRRQQAREDREGNNSS 246
                 :.:.|||::||:.|:||||||.|.||..|.|         ...:..|.:..|:|.....|
Zfish   190 -----FDFHRGFESDITPEDLFNMFFGGSFPSSNSHEFTNGRTYSHHTEETRGERVEERGDGGFS 249

  Fly   247 ALVNLLPIVLLIGLSMMSSFFISDPMYSL--TPSHKYSVKRETNSLKVPYYVKDNFYSEYQGS-V 308
            ..:.|:|||:|:.:|::|...:|.|.|||  .||...:|||:|.:|.|.|:|..:|.|||:|| :
Zfish   250 MFIQLMPIVVLVLVSILSQLLVSTPPYSLYSRPSTGQTVKRQTENLHVDYFVTTDFKSEYKGSAL 314

  Fly   309 ARLEESVEEDFVNHLKHSCSRERNYRDSMLAKARTFGDRDLYRKAQNINTPSCENLQK 366
            .::|:|||||:|::::::|.:||..:..:|..|:.:.|..|.|||:.:...:|:.|.:
Zfish   315 LKIEKSVEEDYVSNVRNNCWKERQTKTDLLYAAKVYRDERLQRKAELMTMENCKELDR 372

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3061	NP_650328.1	DnaJ	105..>224	CDD:223560	60/118 (51%)
		DnaJ	106..167	CDD:278647	36/60 (60%)
		DUF1977	269..366	CDD:286411	40/99 (40%)
dnajb14	NP_001071255.1	DnaJ	110..>218	CDD:223560	60/118 (51%)
		DnaJ	111..172	CDD:278647	36/60 (60%)
		DUF1977	272..372	CDD:286411	40/99 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170589208
Domainoid	1	1.000	97	1.000	Domainoid score	I7174
eggNOG	1	0.900	-	-		E2759_KOG0714
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	321	1.000	Inparanoid score	I2498
OMA	1	1.010	-	-		QHG55696
OrthoDB	1	1.010	-	-		D1173544at2759
OrthoFinder	1	1.000	-	-		FOG0001005
OrthoInspector	1	1.000	-	-		otm25837
orthoMCL	1	0.900	-	-		OOG6_101281
Panther	1	1.100	-	-	O	PTHR43908
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2148
SonicParanoid	1	1.000	-	-		X535
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.800